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Johnbosco

@biocodebreaker.bsky.social

Bioinformatician | Cancer Omics | Health informatics | FAIR Principles | Reproducible Research https://orcid.org/0000-0002-2355-8475

110 Followers  |  1,124 Following  |  21 Posts  |  Joined: 23.03.2025  |  1.9518

Latest posts by biocodebreaker.bsky.social on Bluesky

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I often find my students' code is littered with dependencies that are loaded and then not used. This is a bad coding practice, but it's also very boring to check.

I updated {psychdsish} to include a function that does this for you.

23.08.2025 08:43 β€” πŸ‘ 34    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1

I'm so glad you provided the code used to produce the Figures. Most repositories don't include code for reproducing the Figures. Thanks πŸ€πŸ‘

23.08.2025 08:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Slide designs that present themselves: The assertion–evidence template Your slides are not your talk.

A simple design framework that will massively improve your slides and your public speaking
clauswilke.substack.com/p/slides-tha...

15.08.2025 11:10 β€” πŸ‘ 109    πŸ” 49    πŸ’¬ 2    πŸ“Œ 6
Highly accurate assembly polishing with DeepPolisher An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms

Anyone have difficulty accessing the Cold Spring Harbor Laboratory site? I haven't been able to access it in a long time! Perhaps I should try using a VPN?

genome.cshlp.org/cgi/doi/10.1...

@cshlnews.bsky.social

13.08.2025 09:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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GPT-5: It Just Does Stuff Putting the AI in Charge

open.substack.com/pub/oneusefu...

07.08.2025 18:20 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@laurendsnyder.bsky.social thought you might find this interesting.

07.08.2025 18:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Just curious, are you able to reproduce this now? I couldn't reproduce it.
Just read this somewhere:
[remember when AI couldn’t count the number of Rs in β€œstrawberry”? that was eight months ago).]

07.08.2025 17:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Verified rΓ©sumΓ©s? Or give Bioinformatics tasks on the application call that require at least 6 hours to complete.

05.08.2025 20:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

New #bioinformatics Scientist opening at @officialatcc.bsky.social ! Love #genomics? Want to help build a digital biology future? We're sequencing our entire collection 😱 Our focus? Authenticated Reference Data. Digital Standards. Reproducibility. Join us! careers-atcc.icims.com/jobs/4000/sc...

04.08.2025 20:01 β€” πŸ‘ 4    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

www.nature.com/articles/s44...

20.07.2025 17:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image 20.07.2025 17:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
Ten Simple Rules for Reproducible Computational Research

2. Ten Simple Rules for Reproducible Computational Research
journals.plos.org/ploscompbio...

12.07.2025 13:15 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
microPublication - Get Your Data Out, Be Cited

I love the idea of "micropublications" www.micropublication.org (preparing one now)

14.07.2025 08:29 β€” πŸ‘ 86    πŸ” 16    πŸ’¬ 4    πŸ“Œ 4

What can scientists or the public do when a publication says "data or code available upon reasonable request" - but the author doesn’t respond or refuses to share?

#reproducibility #openscience #opensource #dataaccess #researchintegrity #AcademicSky #EduSky

11.07.2025 18:58 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

While authors were extremely or very helpful for 41% of experiments, they were minimally helpful for 9% of experiments, and not at all helpful (or did not respond to us) for 32% of experiments.

#Reproducibility
#CancerResearch

12.07.2025 18:47 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Reproducibility in Cancer Biology: Challenges for assessing replicability in preclinical cancer biology A project to repeat experiments from high-impact papers in cancer biology encountered a series of challenges, many of which were caused by a lack of detail in the original papers.

Moreover, despite contacting the authors of the original papers, we were unable to obtain these data for 68% of the experiments.

elifesciences.org/articles/67995

12.07.2025 18:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Reproducibility in Cancer Biology: Challenges for assessing replicability in preclinical cancer biology A project to repeat experiments from high-impact papers in cancer biology encountered a series of challenges, many of which were caused by a lack of detail in the original papers.

Reproducibility Project: Cancer Biology to investigate the replicability of preclinical research in cancer biology.

Conclusion: it is hard to assess whether reported findings are credible.

elifesciences.org/articles/67995

12.07.2025 18:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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CODECHECK in Practice: How TU Delft and 4TU.ResearchData Are Making Reproducibility Happen How can we make reproducibility a routine part of the publishing process? That question is at the heart of a new pilot bringing together the TU Delft Digital Competence Centre (DCC) and the 4TU.Res…

❓How can we make reproducibility a routine part of the publishing process❓

CODECHECK is a community-led initiative that helps verify the computational reproducibility of #scientific research. Read more on its application on our website:

community.data.4tu.nl/2025/07/09/c...

09.07.2025 13:32 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 2
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Why does reproducibility matter and how to achieve it? This session explores the importance of reproducibility in research and how 4TU.ResearchData supports researchers in making their work more transparent and trustworthy. We’ll reflect on how 4TU.Res…

Are #engineering and #design research processes reproducible? Join the lunch session "Why does reproducibility matter and how to achieve it?" at @tue.nl on 17 June! See how 4TU.ResearchData piloted the facilitation of reproducibility checks within the #CODECHECK initiative ⬇️

shorturl.at/qyXkc

11.06.2025 12:55 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

x.com/kyleichan/st...

10.07.2025 16:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Kyle Chan on X: "China’s scientific progress is real. Citation counts can be gamed. There is some fraud. And Chinese researchers have been incentivized with cash to target top journals. But the Nature Index, which looks at contributors to 145 top international journals, is solid. 1/ 🧡 https://t.co/8jZed6dpQU" / X China’s scientific progress is real. Citation counts can be gamed. There is some fraud. And Chinese researchers have been incentivized with cash to target top journals. But the Nature Index, which looks at contributors to 145 top international journals, is solid. 1/ 🧡 https://t.co/8jZed6dpQU

x.com/kyleichan/st...

10.07.2025 16:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

Yes, you would think that the norm now sh'd be to run the code to reproduce the figures in the manuscript during review. But alas, the computing environment in which the data was analyzed such as the package versions used are rarely provided hence reproducibility is a nightmare or just impossible!

10.07.2025 16:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
America’s brain drain

America’s brain drain

No words

30.05.2025 12:23 β€” πŸ‘ 1140    πŸ” 410    πŸ’¬ 62    πŸ“Œ 76

In your experience, having in mind that Air Transport remains the safest means of transport, has there been increase in the frequency of aviation disasters in the last five years or there is increased reporting/coverage?

31.05.2025 16:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
R Consortium Awards First Round of 2025 ISC Grants – R Consortium The R Consortium’s Infrastructure Steering Committee (ISC) is proud to announce the first round of 2025 grant recipients. These seven projects are receiving support to enhance and expand the capabilit...

The Round 1 grants from the R Consortium Infrastructure Steering Committee have been announced. This is one of my favorite things about this working for this org. #rstats
r-consortium.org/posts/r-cons...

29.05.2025 16:32 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

A good number of academics Left Twitter/X for good yet on Bluesky or Mastodon there is little to no traction. Twitter was good for making noise. I hope this battle is also happening on Twitter.

30.05.2025 07:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Machine learning algorithm brings long-read sequencing to the clinic SAVANA is a new tool designed for accurate detection of structural variations in clinical samples.

Long-read sequencing can reveal hidden cancer mutations, but existing tools often produce false positives.

SAVANA is a machine learning algorithm trained on cancer genomes, built to make analysis faster and clinically reliable.

@isidrolauscher.bsky.social

www.ebi.ac.uk/about/news/r...

#oncosky

29.05.2025 08:54 β€” πŸ‘ 38    πŸ” 8    πŸ’¬ 1    πŸ“Œ 2

Hi Nick, is Mastodon doing any better? Just figured out how to follow people on different servers, took me a while.

28.05.2025 18:33 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Can this work for panel figures like Fig. A-F as required by manuscripts? I have been using GIMP to put the panels together.

21.05.2025 07:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
useR! 2025

I'll be leading a workshop with Justin Landis at useR! in Durham on August 8. It will be a gentle introduction to how we model biological data using tidy data principles

user2025.r-project.org

20.05.2025 12:05 β€” πŸ‘ 32    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0

@biocodebreaker is following 20 prominent accounts