C. Harris Floudas's Avatar

C. Harris Floudas

@floudas.bsky.social

Personal views (mirroring @chfloudas@mstdn.social account) Med Onc, HNC, Immuno-Oncology, Computational Oncology, AI/ML. linkedin.com/in/floudas Bethesda, MD 🇬🇷 🇺🇸

83 Followers  |  143 Following  |  5 Posts  |  Joined: 17.11.2024  |  1.8625

Latest posts by floudas.bsky.social on Bluesky

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Google’s top AI scientist says ‘learning how to learn’ will be next generation’s most needed skill.

#Greece
apnews.com/article/gree...

12.09.2025 21:03 — 👍 2    🔁 1    💬 0    📌 0

End of an era

03.09.2025 10:17 — 👍 15    🔁 4    💬 1    📌 0

I am so sorry. I know how much this means to my lovely British friends, but here is a black-figure neck amphora from around 500 BCE painted by Plousios, depicting Athenians queuing at a shoe shop and a blacksmith, on either side.

24.08.2025 13:50 — 👍 204    🔁 25    💬 23    📌 1
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There’s a persistent myth that new solar farms don’t really help tackle climate change because panels are “made with coal” and “never pay back” their carbon debt.

This is simply false.

- UN: solar ~8x cleaner than gas, ~19x than coal per kWh
- panels repay CO2 in 4 months; save 57x over life

30.08.2025 08:46 — 👍 2463    🔁 888    💬 66    📌 30
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A new layer of security for certified Android devices Starting in 2026 and in select countries first, Android apps must be registered to a verified developer in order to be installed.

Google will verify the real-world identities of all Android app developers starting September 2026.

The new rule will apply to all apps, even those distributed outside of the official Play Store.

android-developers.googleblog.com/2025/08/elev...

26.08.2025 10:39 — 👍 9    🔁 5    💬 3    📌 0
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Beach on a budget: Greeks settle for day trips, priced out of iconic destinations Greece’s booming tourism industry is drawing huge numbers of foreign visitors, but many Greeks are struggling to afford holidays in their own country.

The growing demands of the holiday industry and leisure inflation have reshaped Greek summers.

#Greece
apnews.com/article/gree...

26.08.2025 09:22 — 👍 3    🔁 4    💬 0    📌 0
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Μπορεί να σωθεί το ελληνικό καλοκαίρι; Η εμπειρία του ελληνικού καλοκαιριού αλλάζει. Μπορεί η προσδοκία του κέρδους να συνδυαστεί με ένα άλλο μοντέλο; Υπάρχει «τρίτος δρόμος» μεταξύ του κορεσμού και της πλήρους απόρριψης;

Ένα εμπεριστατωμένο άρθρο του Στάθη Καλύβα για τα αδιέξοδα της εθνικής τουριστικής "στρατηγικής" και το πώς μπορει η χώρα να διαχειριστεί βιώσιμα τις διαρκώς αυξανόμενες ροές: www.kathimerini.gr/life/5637770...

26.08.2025 09:23 — 👍 1    🔁 1    💬 0    📌 0
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Phishing Emails Are Now Aimed at Users and AI Defenses Phishing has always been about deceiving people. But in this campaign, I discovered something new. The attackers weren’t only targeting users, they also attempted to manipulate AI-based defences. T…

Is this the first attempted AI prompt injection spotted in the wild?

malwr-analysis.com/2025/08/24/p...

24.08.2025 12:36 — 👍 18    🔁 11    💬 1    📌 0
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Offering “life-sustaining” treatment without compromising quality of life | Center for Cancer Research When Alison James received her diagnosis of squamous cell carcinoma, she was alarmed by the side effects associated with the standard of care. She traveled to the NIH Clinical Center for a CCR clinica...

NCI blog patient story for trial NCT06223568 #neoadjuvant chemo (cisplatin&docetaxel) & #HPV #immunotherapy (PRGN-2009) for newly diagnosed HPV-positive OPSCC (PI Dr Clint Allen): omission of adjuvant radiotherapy per response to neoadj Tx & surg path risk factors.

ccr.cancer.gov/news/article...

02.05.2025 16:24 — 👍 1    🔁 0    💬 0    📌 0

Interesting presentation to the intramural NCI by @dinler.bsky.social about the HLA-Arena environment.

30.04.2025 14:45 — 👍 2    🔁 0    💬 0    📌 0
Kombucha girl maybe meme.
On the left, frowny face: working on an important manuscript
On the right, intrigued: spending two hours to create a figure that came to my mind quite randomly

Kombucha girl maybe meme. On the left, frowny face: working on an important manuscript On the right, intrigued: spending two hours to create a figure that came to my mind quite randomly

08.04.2025 14:27 — 👍 271    🔁 26    💬 16    📌 12

A thoughtful discussion about dose, duration, and frequency of ICBs in the NSCLC context. Are we overtreating?
https://ascopubs.org/doi/abs/10.1200/JCO-24-02347

04.04.2025 12:32 — 👍 0    🔁 1    💬 0    📌 0

"Childhood cancer survivors have >2x risk of melanoma compared to the general population and those with an invasive melanoma have>2x risk of death."

https://ascopubs.org/doi/abs/10.1200/JCO-24-01519

03.04.2025 13:02 — 👍 0    🔁 1    💬 0    📌 0
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Make bold predictions and then test them. This is the true legacy of Karl Popper, who argued that the strength of an idea lies in its ability to make surprising predictions; ones that, if shown to be wrong, would falsify it.

31.03.2025 17:32 — 👍 50    🔁 12    💬 2    📌 1
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This is totally true for me!

26.03.2025 12:05 — 👍 98    🔁 17    💬 6    📌 2
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Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo - Nature Biotechnology Profiling transcriptional crosstalk between promoters and cell-type-specific enhancers allows large gene cargo delivery.

Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo - @caltech.edu @asapresearch.bsky.social go.nature.com/4kFUnEO

20.03.2025 17:14 — 👍 8    🔁 5    💬 0    📌 0

Explainable AI reveals Clever Hans effects in unsupervised learning models
https://www.nature.com/articles/s42256-025-01000-2

20.03.2025 17:32 — 👍 2    🔁 2    💬 0    📌 0

Low rate of regular activity for the Med, esp. Greece. Considering also smoking patterns and a much changed diet, the pop health stats will be very interesting.

18.03.2025 12:48 — 👍 1    🔁 0    💬 0    📌 0

A case-control study in twins, from Denmark: "Tattoo ink exposure is associated with lymphoma and skin cancers"

BMC Public Health
https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-025-21413-3

16.03.2025 11:08 — 👍 0    🔁 1    💬 0    📌 0
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Trends in Cervical Precancers Identified ... This report describes decreases in cervical precancer incidence among women ages 20-24 years.

"During 2008–2022, cervical precancer incidence decreased 79% and higher-grade precancer incidence decreased 80% among screened women aged 20–24 years, the age group most likely to have been vaccinated."

www.cdc.gov/mmwr/volumes...

15.03.2025 15:33 — 👍 1    🔁 0    💬 0    📌 0
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Griechenland: Müll an den tiefsten Stellen im Mittelmeer gefunden Mit einem speziellen U-Boot sind Forschende zum Calypsotief vor Griechenland getaucht. Bilder zeigen menschliche Spuren in über 5000 Meter Tiefe.

Mit einem speziellen U-Boot sind Forschende zum Calypsotief vor Griechenland getaucht. Bilder zeigen menschliche Spuren in über 5000 Meter Tiefe.

12.03.2025 19:18 — 👍 28    🔁 11    💬 4    📌 0
Homepage - openRxiv openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

11.03.2025 13:20 — 👍 2571    🔁 849    💬 55    📌 42
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Extracellular vesicles for the delivery of gene therapy - Nature Reviews Bioengineering Extracellular vesicles can be designed to serve as delivery platforms for gene therapy. This Review discusses the application and engineering of extracellular vesicles for different gene-therapy modalities, outlining crucial steps to advance this technology into the clinic.

Extracellular vesicles for the delivery of gene therapy
https://www.nature.com/articles/s44222-025-00277-7

06.03.2025 16:37 — 👍 3    🔁 1    💬 0    📌 0
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Something motivational for your LinkedIn page…

03.03.2025 12:05 — 👍 90    🔁 12    💬 0    📌 0
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Στα σκαριά 48 νέα ξενοδοχεία στη Μήλο Η κατασκευή κοντά στο Σαρακήνικο είναι μόνο ένα μικρό μέρος της οικοδομικής δραστηριότητας που θα προσθέσει στο νησί έως και 2.674 κλίνες. Τι έδειξε η έρευνα της «Κ».

Η Μήλος αλλάζει πρόσωπο, για πάντα. Ούτε ένα ούτε δύο, αλλά 48 ξενοδοχεία δρομολογουνται στο νησί, παράλληλα με τις εκατοντάδες οικοδομικές άδειες για ενοικιαζόμενα δωμάτια και βίλες. Η Πολιτεία κοίτα απαθής, ενώ ένα ένα τα κυκλαδονησια καταστρέφονται.
www.kathimerini.gr/society/5634...

24.02.2025 15:10 — 👍 24    🔁 25    💬 2    📌 7
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Ipilimumab plus nivolumab versus nivolumab alone in patients with melanoma brain metastases (ABC): 7-year follow-up of a multicentre, open-label, randomised, phase 2 study Our findings suggest that ipilimumab plus nivolumab maintains efficacy to at least 7 years in patients with active asymptomatic brain metastasis. Upfront ipilimumab plus nivolumab should be the standa...

So proud of this aussie trial - changed practice. @melanomaau.bsky.social @sydneyuni.bsky.social
@science.org.au
Ipilimumab + nivolumab vs nivolumab in patients with #melanoma brain metastases (ABC): 7-yr follow-up of randomised, ph 2 study - The Lancet Oncology www.thelancet.com/journals/lan...

18.02.2025 12:28 — 👍 10    🔁 5    💬 0    📌 2
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On a Mission to Heal Gila Monsters (Gift Article) After years in Big Pharma, a chemist pivoted to help save the species that made Ozempic possible.

From Gila monsters and Ozempic to Cryptosporidium - what a cool piece on basic science www.nytimes.com/2025/02/16/s...

16.02.2025 13:13 — 👍 3    🔁 4    💬 0    📌 0
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Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy - Nature Communications This study describes structures of the transcription factor brachyury revealing the mechanism of DNA recognition. They identify fragments using X-ray fragment screening and optimize these into potent ligands with potential as cancer therapeutics.

Crystallographically identified hotspots on the brachyury surface - potential for chordoma therapeutics

Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy
https://www.nature.com/articles/s41467-025-56213-1

15.02.2025 16:43 — 👍 1    🔁 2    💬 0    📌 0

p16 expression confers sensitivity to CDK2 inhibitors https://www.biorxiv.org/content/10.1101/2025.02.10.637344v1

15.02.2025 15:48 — 👍 2    🔁 1    💬 0    📌 0
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GitHub enables collaborative and reproducible laboratory research GitHub, a platform widely used in software development, offers a robust framework for documenting all activities of laboratory research projects. This Community Page highlights the benefits of, and pr...

1, 2, 3, 4.
"Electronic lab notebooks, despite their popularity, are stored in proprietary formats, incur a recurrent cost, tend to become defunct over time, and have poor interoperability with each other"
journals.plos.org/plosbiology/...

15.02.2025 12:18 — 👍 32    🔁 9    💬 0    📌 0

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