Dr. Keith R. Brunt

Any thoughts on comparison to he Rose Bengal photothrombotic stroke model?

A minimally invasive thrombotic model to study stroke in awake mice - Nature Communications Rodent stroke models are crucial but often invasive and limited in translational relevance. Here, the authors show that magnetic particle delivery creates a reproducible, minimally invasive thrombotic...

A new magnetic particle mouse model of stroke

Importantly, no craniotomy is required, avoiding a major confounder that causes massive surgery-induced inflammation.

Read the article "A minimally invasive thrombotic model to study stroke in awake mice"
www.nature.com/articles/s41...

Many and diversely, Olympics just hasn't been one.

Nope. I don't watch so long as there are ruzzians participating, and the IOC doing backflps for them, while also sanctioning Ukrainians for remembering lost athletes. It's the hypocrisy that robs joy.

Antarctic researchers solve long-standing Blood Falls mystery Antarctic glacier bleeds red water, and scientists reveal hidden pressure beneath the mysterious millennial ice.

Fun little paper we published last month got picked up by earth.com. The author got it mostly right. There was no press release so he seemed to go above and beyond and read the paper and some citations in it and used references. Nice work. #scicomm 🧪 www.earth.com/news/antarct...

Good luck!!

Can you expand on weird results? Is reference curve in order? Have you tried adding a small spike to the mid range of a reference to see if it moves it up or down the line? Sorry, don't have specific knowledge of re: sample prep, but working the bugs out of Cayman kits is my jam (pH, salts, protein)

Building a Life in Science Against the Odds A physiologist reflects on resilience, resourcefulness, and building a successful research career in unconventional and often challenging environments.

APS member Douglas R. Seals overcame a series of challenges to forge a successful career in science. "You, not your environment, are the master of your fate," he says.

Read more about his journey in the January issue of #TPhysMag: https://ow.ly/8H0m50YeERN #Physiology #Inspiration 🧪

Did you check the pH with a test strip? Lizards and birds can be high in uric acid, might be a compatability range issue. (If so, input NaOH/KOH to tolerance range of assay?)

Researchers discovered a new photoreceptor!

A hybrid rod-like cone is found in some fish species that live at depths of up to 200 m allowing them to see in gloomy water.

Read the OPN story: https://bit.ly/40kKXW8

#vision #photoreceptor #technology 💡 ⚛️ 🧪

I did this once. It was fun.

SCIENCE IRL: SciComm mini-grant 2026 Skype a Scientist is offering $300-$1,000 mini-grants to support boots-on-the-ground science communication. The Science IRL mini-grants will support projects that put either 1) important science mess...

Skype-a-scientist does small grants ($300-$1000) for creative #SciComm projects in your local community! You don't have to be a scientist to apply.

docs.google.com/forms/d/e/1F...

🧪 #BlueSci

What is interesting is that shots are often being delivered (unconsciously or manipulatively) by those who contribute the free intellectual labour.

Have you found yourself aligned in one of the 3 camps? How did you get there? Ever felt that you were criticized for picking a certain journal?

2/2

🧪 An interesting 3-way competition continues to take form (& shots at each other) in scientific publishing.
Society, Open Access, & Traditional Publishers.
All are accused of "impact" flaws, inaccessibility, citation gaming, predatory practices, or profiteering from free intellectual labour. 1/2

I like science, give me a follow and I'll follow back - medicine, pharmacology and physiology!

FDA refuses to review Moderna’s application for mRNA flu vaccine, company says | CNN The US Food and Drug Administration has refused to accept an application from Moderna to review its first mRNA seasonal flu vaccine, the company said Tuesday, in another setback for the technology tha...

This is where my prediction comes true: the insane opposition to mRNA vaccines, without any scientific basis, is going to start killing people. Tip of the iceberg, and we’re all on the boat. 🧪 ⚕️ #medsky

The Surprising Drink Doctors Always Recommend When You’re Sick Feeling under the weather? The right drink can make all the difference when you’re sick. Find out which choice health experts recommend for hydration, recovery, and comfort.

We’re always told to drink more when we’re sick, but what works best? Turns out the answer is simple. Experts say plain water is king and may even help keep stress hormones in check, per a cited APS Publications JAPPL study. More from Real Simple: https://ow.ly/HWWg50Y7I1L #ISpyPhysiology 🧪

I’m back here to share our new pre-print! 🔬 🧬 😃

Proteo-transcriptomics and morphometrics of teleost cardiac cells define regulatory networks and exercise-induced cardiomyocyte hypertrophy and hyperplasia

Flow cytometry+Imaging+RNA-seq+Proteomics

Preprint available on bioRxiv [link in comments]

Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis Current evidence does not indicate a clinically important increase in the likelihood of autism spectrum disorder, ADHD, or intellectual disability in children of pregnant individuals who use paracetam...

Not that most rational people would need to hear this--it is reassuring to know that scientists take the time to evaluate & show that #Acetaminophen aka #Tyelenol aka #Paracetemol when used in #pregnancy DOES NOT have any associations with #Austism spectrum 🧪🧠 www.thelancet.com/journals/lan...

Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis Current evidence does not indicate a clinically important increase in the likelihood of autism spectrum disorder, ADHD, or intellectual disability in children of pregnant individuals who use paracetam...

Not that most rational people would need to hear this--it is reassuring to know that scientists take the time to evaluate & show that #Acetaminophen aka #Tyelenol aka #Paracetemol when used in #pregnancy DOES NOT have any associations with #Austism spectrum 🧪🧠 www.thelancet.com/journals/lan...

This review surveys animal models of #MenieresDisease, progress in #genetic, #immune, and allergic mechanisms, and current treatments, highlighting strengths, limitations, and gaps that must be addressed to build a framework for future research.

#OpenAccess: doi.org/10.1016/j.ge...

I was curious, so I looked this up. There has been a long-running study mapping such things since 1995-2025 (wow, 30 years running).

Record History | ver. 345: 2025-12-24 | NCT00001467 | ClinicalTrials.gov share.google/jkBKhBxKHVTT...

I am sorry that your families are impacyed in multiple ways, it cant be easy on anyone. It is interesting how these clustered, if you ever have the chance to do clinical genetic sequencing, it could be helpful to future studies. I wonder if there are some more linkages to be discovered still.

Very!

It really is!! Hang in there all.

No cap! Gets even other scientists excited - total fire.

So many stories like this matter. I’m sorry for your Dad, but in future you and your family will have the chance to look back on the science his life inspired - and hold dear all the good memories of him, independent of the MA. ♥️

Yeah, this will be a major catalyst-reading papers doesn’t usually give me “chills” of excitement.

Yes, while therapies have improved greatly this could change the entire paradigm at this point. I’m already speculating as to which major pharmaceutical & biotechnology CSO has set projects in motion on this.

For sure, and we have the tools to fight off these “innocuous” viruses