Yale Center for Systems and Engineering Immunology

Research The immune system is a spatially distributed, whole-body sensory-reactive system that monitors, reacts, and adapts to various stress signals (e.g., tissue

We have some news to share: The Kueh lab is moving to ‪Yale this fall!‬ We will be joining the Yale Center for Systems and Engineering Immunology ‪@yalecsei.bsky.social‬ and the Department of Immunobiology.

medicine.yale.edu/systems-engi...

@yalecsei.bsky.social and @yalecancer.bsky.social were honored to co-host Jon Cohen (VP) and Laksshman Sundaram (Sr Mgr) from Applied Research at NVIDIA for a special seminar on virtual cell modeling. Dr. Sundaram gave a great overview on the approaches he is using to model basic cellular processes.

Picture of some of our amazing workshop presenters.

Thank you #CZBiohubNY Mini Workshop presenters and attendees! Great talks by @czbiohub.bsky.social and @yaleschoolofmed.bsky.social scientists. Grateful to #CZI and @tsanglab.bsky.social for bringing us together. Thank you Susan Rosenthal, Elizabeth Ferris and Lital Manor for superb event logistics.

Session 5 - Single Cell/ Technology: Tim Olsen (CZ Biohub Platform Leader); Andrew Martins (Yale Assistant Professor of Immunobiology); Mark Lee (Yale Assistant Professor of Laboratory Medicine); Marcus Bosenberg (Yale Anthony N. Brady Professor of Dermatology)

Session 4 - Immunology: Roham Parsa (CZ Biohub NY Group Leader); Ya-Chi Ho (Yale Associate Professor of Microbial Pathogenesis); Carrie Lucas (Yale Associate Professor of Immunobiology); Lauren Sansing (Yale Professor of Neurology)

Session 3 - Immune Cell Engineering: Sjoukje Van der Stegen (CZ Biohub NY Platform Leader); Sidi Chen (Yale Associate Professor of Genetics and of Neurosurgery); Etienne Caron (Yale Assistant Professor of Immunobiology)

Session 2 - Machine Learning: Evan Paull (CZ Biohub AI/ML Platform Leader); Steve Kleinstein (Yale Anthony N Brady Professor of Pathology); Gur Yaari (Yale Associate Professor of Pathology)

Session 1 - Systems Biology: Andre Levchenko (Yale John C. Malone Professor of Biomedical Engineering); Andres Hidalgo (Yale Professor of Immunobiology); Jennifer Kwan (Yale Assistant Professor of Medicine); Peter Sims (Columbia Associate Professor of Systems Biology)

Exciting lineup at today's #CZBiohubNY Mini Workshop hosted by @yalemedicine.bsky.social, @tsanglab.bsky.social and @yalecsei.bsky.social. Thrilled to welcome @czbiohub.bsky.social and @chanzuckerberg.bsky.social investigators and team members to Yale for this day of science and interaction.

Thrilled to have Dr. Arjun Raj (@pennmedicine.bsky.social) present the inaugural Trainee Invited @yalecsei.bsky.social Seminar this week - "Can Cells Learn?"! @arjunraj.bsky.social thank you for sharing your findings on how cells respond to challenges and immune cell memory. #YaleCSEI

@yalecsei.bsky.social was honored to have Rafick Sékaly (Prof @emoryuniversity.bsky.social) present a special seminar on the "Host environment shapes the protective immune response to viral infections", with a focus on bile acids and their affect on monocyte-driven inflammation. #YaleCSEI

Exciting talk by Purvesh Khatri (Prof. of Med. at @stanforduniversity.bsky.social) at today's @yalecsei.bsky.social Seminar on his work "Translating computational analysis into clinical practice using in silico systems analysis". Inspiring work to improve acute infection detection in the clinic!

Learned about immune aging at @yalecsei.bsky.social Seminar today. Thank you Duygu Ucar (Professor at @jacksonlab.bsky.social) for a great talk on how the human immune system changes with age and how gender and hormonal differences can affect immune responses to vaccination and infection.

Lovely @yalecsei.bsky.social Seminar today by Michael Lässig (Prof. of Physics @unicologne.bsky.social) on "Predicting the evolution of Influenza and SARS-CoV-2". Will be visiting Previr.com for fast evolving viral predictions! #YaleCSEI #fitnessmodels

Learned about cell membrane dynamics at this week’s @yalecsei.bsky.social Seminar by Min Wu (Assoc. Prof. Cell Biology @yaleschoolofmed.bsky.social)! Great presentation/discussion on complexity in modeling and understanding oscillating reactions that move across perturbed cell membranes. #YaleCSEI

Enjoyed the informative Boolean modeling crash course and interesting discussion on developmental epigenetic and gene expression regulation in cells prior to cancer emergence at yesterday's CSEI Chalk Talk by Dr. Andre Levchenko (John C. Malone Professor of Biomedical Engineering, Yale)! #YaleCSEI

#YaleCSEI had the pleasure of hosting Dr. Nicolas Chevrier (Assoc Prof at #UChicagoPME) today! Dr. Chevrier presented on using his group's ArraySeq technique to conduct spatial genomic profiling on whole-murine sections. An interesting approach to analyze organism-wide responses to perturbations!

Over the past year I gave some lectures on AI and Immunology including the keynote at NIAID and GSK Palio Meeting. I've been asked about sharing my slides, here they are:

1. slides: zenodo.org/records/1425...

2. NIAID meeting report: rdcu.be/d1VRw

3. Related: www.dropbox.com/scl/fi/y67z0...

I created a starter pack for systems immunology - let me know if you would like to be added. Excited to be here on
@bsky.app

go.bsky.app/PjH2Fuj

Hello Bluesky Community! The Yale Center for Systems and Engineering Immunology is here. Excited to join and contribute to the conversation!

Learn more about us at: medicine.yale.edu/systems-engi...

#YaleCSEI #systemsimmunology #immunology
@yalecsei.bsky.social