bioRxiv Genetics

Functional characterization of the 9q34.13 locus identifies RAPGEF1 as modulating risk for melanoma and nevi via RAS activation https://www.biorxiv.org/content/10.64898/2025.12.03.691936v1

A genomic toolkit for surveillance and elimination of the principal malaria vectors in Southeast Asia. https://www.biorxiv.org/content/10.64898/2025.12.04.691712v1

Tripartite AAV Systems for EYS Retinal Gene Therapy https://www.biorxiv.org/content/10.64898/2025.12.03.692187v1

Resolving the CES1 Genomic Locus with Cas9-Directed Targeted Long-Read Sequencing for Precision Pharmacogenomics https://www.biorxiv.org/content/10.64898/2025.12.03.692062v1

WormTagDB: A Systematic Survey of Endogenously Tagged Proteins in C. elegans and Roadmap Towards the Tagged Proteome https://www.biorxiv.org/content/10.64898/2025.12.02.691955v1

Mitochondrial redox homeostasis links organellar stress surveillance to germline and somatic integrity in Caenorhabditis elegans https://www.biorxiv.org/content/10.64898/2025.12.03.691999v1

Distinct Myogenic Stages Recapitulate Transcriptomic Networks in COPD Cachexia https://www.biorxiv.org/content/10.64898/2025.12.03.692216v1

Parental Influence on Children's Educational Achievements: Analysing Direct and Indirect Genetic Effects through Trio-GCTA https://www.biorxiv.org/content/10.64898/2025.12.03.691991v1

Quantifying the susceptibility of polygenic scores to ancestry stratification https://www.biorxiv.org/content/10.64898/2025.12.04.692430v1

Allelic chromatin structure is a pervasive feature of imprinted domains and functions cooperatively with cis-acting long non-coding RNAs https://www.biorxiv.org/content/10.64898/2025.12.02.691962v1

Sir proteins impede, but do not prevent, access to silent chromatin in living Saccharomyces cerevisiae https://www.biorxiv.org/content/10.64898/2025.12.02.691921v1

Assembly of a pangenome uncovers novel non-reference unique insertion sequences in cattle highlighting their genetic diversity https://www.biorxiv.org/content/10.64898/2025.12.02.691810v1

Sperm-specific fertility factors SMZ-1/2 promote FB-MO biogenesis and MSP filament assembly in C. elegans https://www.biorxiv.org/content/10.64898/2025.12.01.691703v1

HID1 domain-containing protein 1 is required for normal cell proliferation in Schizosaccharomyces pombe https://www.biorxiv.org/content/10.64898/2025.12.02.691498v1

Enhancer-directed gene delivery for digit regeneration based on conserved epidermal factors https://www.biorxiv.org/content/10.64898/2025.12.01.691633v1

Integrating Enviromics to Predict Performance and Guide Clonal Deployment in Eucalyptus spp. https://www.biorxiv.org/content/10.64898/2025.12.01.691191v1

Mistranslation protects against lifespan reduction due to mating in Drosophila melanogaster females. https://www.biorxiv.org/content/10.64898/2025.12.01.691645v1

Fetal influence on maternal pregnancy through the Peg3 imprinted domain https://www.biorxiv.org/content/10.64898/2025.11.28.691217v1

Phosphatidylinositol Transfer Protein-1 Integrates Insulin/IGF-1 and TOR Signaling to Negatively Regulate Lifespan and Healthspan in Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.11.28.691094v1

Geography and forest naturalness as drivers of genetic diversity in saproxylic beetles https://www.biorxiv.org/content/10.1101/2025.11.29.691121v1

Nucleolar Cdc14 Splitting Reflects Recombination Context and Meiotic Chromosome Dynamics https://www.biorxiv.org/content/10.1101/2025.11.27.691012v1

A single Musashi gene allele is sufficient to maintain mouse photoreceptor cells https://www.biorxiv.org/content/10.1101/2025.11.26.690869v1

A population genetics model explaining overdispersion in active transposable elements https://www.biorxiv.org/content/10.1101/2025.11.27.691047v1

The globally dispersed sun-coral species is _Tubastraea coccinea_ (Cnidaria: Anthozoa) https://www.biorxiv.org/content/10.1101/2025.11.26.690498v1

Bayesian inference of population structure using identity-by-descent-based stochastic block models https://www.biorxiv.org/content/10.1101/2025.11.26.690810v1

Functional Landscape of Zebrafish Gonadotropins and Receptors: A Comprehensive Genetic Analysis https://www.biorxiv.org/content/10.1101/2025.11.26.690707v1

Progeny-based genomic selection reveals untapped genetic potential in an underutilized medicinal plant, Perilla frutescens https://www.biorxiv.org/content/10.1101/2025.11.26.690889v1

Adaptive Partial Conjunction Hypothesis: Identifying Pleiotropy Across Heterogeneous Effect Units https://www.biorxiv.org/content/10.1101/2025.11.25.690340v1

mfSuSiE enables multi-cell-type fine-mapping and multi-omic integration of chromatin accessibility QTLs in aging brain. https://www.biorxiv.org/content/10.1101/2025.11.25.690439v1

Oncogenic Ppm1d mutations deregulate the p53 pathway in primary mouse gliomas https://www.biorxiv.org/content/10.1101/2025.11.25.690483v1