Leon-Samuel SPOOKing 👻

@gerrich.bsky.social Buddy are ya now Dr. Buddy?

a pic of tube arrangement of 11 tubes in the centrifuge but it did not look balanced at all (although it is). the 11 tubes were broken down into 3+2+6 groups and within each group it's perfectly balanced on its own.

Showed my students the perfectly balanced chaos I had before and I think they are both inspired and scared lol. #newpi 🧪

I

Best of luck, buddy. Gonna rock it!

CIBBS?

We had excellent timing for Zurich, under 30 min delay so I suppose they'd still let you pass but then elongated their pauses at the stations to get passed the 30 minutes. Threw everyone out in Schaffhausen and went back to Germany

Wow the DB caused some artificial delays just to not go to Zurich. Haven't seen that technique before

Slidev Presentation slides for developers

Anyone here with experience with sli.dev for making slides using Markdown. I saw one example (by @fonnesbeck.bsky.social) that looked absolutely fantastic, so I'm quite interested in giving it a try. Any experience among my followers?

Muyuan Chen has turned structural biology into an immersive experience with his new video game Meowtabolism, now available on Steam.
Try the demo here: store.steampowered.com/app/4045010/...
Give Muyuan feedback: steamcommunity.com/app/4045010
#ScienceGaming #StructuralBiology #CryoEM #STEMOutreach

Un-frigging-believable. I have waited for something like this for so long!

Sadly I have to get off at the next stop and can't keep you updated 😔

Not yet, two apples and a yoghurt have been consumed so far. Now it's time for the bread

Using a German train is not the same without Waldtraud pulling out her 5 star breakfast at some point

On the left - western blot of B16F10 cells wt and KO for CDK8. Our in house produced antibodies give a lot of unspecific bands. On the right same probes with antibodies preincubated with fixed CDK8 KO cells - there is a specific band and faint unspecific bands, which can be probably eliminated with increase of amount of KO cells.

Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky

Test the activity of 300+ natural enzymes against 100+ substrates, discover 200+ new enzymatic reactions, and train machine learning models to predict which enzymes can do which reactions.

@aepaton.bsky.social @gabegomes.bsky.social @alisonnarayan.bsky.social

www.nature.com/articles/s41...

Fantastic!

Membrane trafficking meets root barriers, resilience, and carbon storage 🌱🌍
New discovery: Blocking clathrin-mediated endocytosis in Arabidopsis roots sparks ROS bursts → ectopic suberization. This might unlock ways to increase suberization in roots and C in soils
#PlantScience #RootBiology #Suberin

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! 🧪 jobs.rutgers.edu/postings/260...

They’re coming y’all…the megaplasmids are coming

(I say this in a slightly frustrated manner as someone who has been thoroughly unsuccessful in getting funding to study megaplasmids for the better part of 15 years)

Let's goooo

here are some helpful steps for academics who are considering creating genAI images to use for lab branding:

1. don't

Amazing work by the Santiago lab @unil.bsky.social. The malectin-LRR receptor kinase IGP1 senses cello-oligomers to alert the plant immune system & enhance disease resistance. Very nice discovery & mechanism.
www.biorxiv.org/content/10.1...

Does anyone on Bluesky research proteins that are stable at high temperatures? 👀 #science #biosky #chemsky

You’ve heard of ubiquitination, meet deazaguanylation: Doug Wassarman in our lab discovered phage defense pathways have co-opted Q nucleobase biosynthetic enzymes to catalyze a new form of protein conjugation chemistry @science.org

www.science.org/doi/10.1126/...

Color changing flowers 🧬🎨- attempt #2

Older flowers (bottom) show dark red/ orange tints whereas young buds (top) display strong fuchsia color. Getting closer..

Updated Mineral Cup Bracket covering Round 1, and up to Kosmoschlor and Titanite of Round 2.

Updated bracket.

#MinCup25 ⚒️ sci-fi 🧪 🖖🏼 scifi Geosciences #WomenInSTEM geology 🔭🪐

By author, editor, and reviewer 2

Hello! I'm Behnoush, structural biology scientist from the Broad Institute. I also like to combine proteins structures and other scientific topics with art. Here are some journal cover arts I've created recently. Hope to find old and new friends here.
#Blender #b3d #MolecularNodes #GeometryNodes

A PLETHORA transcription factor shapes cucumber shoot architecture https://www.biorxiv.org/content/10.1101/2025.09.18.677013v1

De novo Design of All-atom Biomolecular Interactions with RFdiffusion3 Deep learning has accelerated protein design, but most existing methods are restricted to generating protein backbone coordinates and often neglect interactions with other biomolecules. We present RFd...

De novo design of All-atom biomolecular interactions with RFdiffusion3 www.biorxiv.org/content/10.1...