Leon-Samuel Icking

The OpenPlant kit is finally available from Addgene as... a kit :)
www.addgene.org/kits/haselof...
@addgene.bsky.social #marchantia #synbio

Unmasking Academe’s Gilded Boys’ Club The Epstein files reveal an elite, chummy, and venal scholarly network.

“...the old conferences did not care about diversity. I suggest you not either,” Epstein wrote to Brockman. “The women are all weak, and a distraction sorry.” 😡👩🏻‍🔬 #AcademicSky

New Ed Yong book in April 2027 let's gooooo

We teamed up with OpenFlower (@nickdesnoyer.bsky.social), a nonprofit creating designer flowers for art & education, to release 3 limited edition postcards! These flowers were powered by Whole Plasmid Sequencing from Plasmidsaurus.

Want one? Just fill out the form!
tinyurl.com/plasmidsauru...

🚀 Excited to launch the #OpenCloning Assembler!

🧬 Built to demystify Golden Gate for beginners and save time for experts -> MoClo assembly blazing fast ⚡

✍️ Use existing syntaxes or design your own!

#SynBio #GoldenGate #MoClo #OpenSource #Biotech

👉 Try it: app.opencloning.org

Feedback welcome!

Dennis nedry jurrasic park "see nobody cares" meme reads Hey everybody, this guy still posts on X! See? Everyone is horrified and disappointed. They feel it speaks directly to your values.

The mechanical properties of Arabidopsis thaliana roots adapt dynamically during development and to stress Brillouin microscopy reveals in vivo dynamics of mechanical properties during plant development and response to stress.

Our work now on its final version. We mapped the mechanical properties of roots at tissue and single cell levels using Brillouin microscopy and molecular rotors. Additional mutants and stress measurements from what we previously showed in the preprint are included.
www.science.org/doi/10.1126/...

DeepL seems to have updated and has removed the "thesaurus" feature. Does anybody know a good alternative to DeepL?

A dual role of Arabidopsis PAL nuclear localization in fine tuning flavonoid biosynthesis PAL’s dual localization links metabolism with transcription, revealing feedback that fine-tunes phenylpropanoid regulation.

Interesting paper: Metabolic enzyme PAL can go into the nucleus in response to high product build up and sequester an activating TF of the pathway, thus acting as a feedback inhibition loop.

From: www.science.org/doi/full/10....
#PlantScience

Very nice genetic dissection of the roles of BSK kinases in brassinosteroid signaling by Wenqiang Tang's lab. bsk-u (ko for BSK1 1, 2, 3, 4, 5, 6, 7, 8, 10, 11 & 12) really looks like a bri1 null mutant and can be rescued by over-expressing BSK3. nph.onlinelibrary.wiley.com/doi/epdf/10....

iGEM Registry The iGEM Registry is a community-curated collection of standardised genetic parts used to design, build and share synthetic biology devices and systems.

Oops, I think this part got all the documentation: registry.igem.org/parts/bba-25.... Or ask Nicole, she'll definetly know

iGEM Registry The iGEM Registry is a community-curated collection of standardised genetic parts used to design, build and share synthetic biology devices and systems.

You could try the one the iGEM team made this year (registry.igem.org/parts/bba-25...), should still be in the Signalhaus. to use it it not as an intermedia but rather as primary, you just have to change the epitope I guess 👍

And save >80% on the cost by pooling 6 or more plasmids into a single sample using our free SAVEMONEY algorithm!

elifesciences.org/articles/88794

colab.research.google.com/github/Masaa...

Transcription terminators can be strong promoters https://www.biorxiv.org/content/10.64898/2026.02.12.705533v1

Thanks Rita, it's not urgent :)

The role of pectate lyases in development and stress tolerance in plants - Molecular Biology Reports Pectate lyases (PLs) are a class of pectin-degrading enzymes that catalyze the β-elimination of de-esterified homogalacturonan in a Ca²⁺-dependent manner, releasing unsaturated oligogalacturonides and...

Does anybody have access to this article?
link.springer.com/article/10.1...

a photo of a fat yellow beetle grub writhing on concrete

does anyone know what kind of beetle this is? inaturalist is just suggesting some kind of scarab. I saw it in the adirondacks by tupper lake in july

A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

Why hasn't this paper gotten more attention?

🔵mTurquoise2-based glucose biosensors TINGL and THINGL from @joachimgoedhart.bsky.social and the Teusink Lab!
Find the plasmids here: www.addgene.org/browse/artic...

PhD opening
Join a collaborative, interdisciplinary project the Excellence Cluster Future Forests @uni-freiburg.de, working on CRISPR/Cas in poplar to understand how trees cope with climate stress.
Apply here: uni-freiburg.de/en/job/00004...
@dompsfr.bsky.social @biologyunifreiburg.bsky.social

We're recruiting a PhD student to try and understand stress memory and gene function, using gene editing, in trees! #plantscience

Exclusive | OpenAI Executive Who Opposed ‘Adult Mode’ Fired for Sexual Discrimination Ryan Beiermeister, who served as the vice president leading OpenAI’s product policy team, had raised concerns about the upcoming launch of erotic content.

OpenAI fired a VP who opposed their erotica rollout (and had started a company-wide peer mentorship program for women), allegedly telling her it was because she discriminated against a man 🤔 www.wsj.com/tech/ai/open...

Why do some scientists say "Bluesky is dead. I have no engagement. I have more engagement on X"? My TL is full of cool science, queer art, weird history facts, politics and whimsy. You're just not doing it right, man. Plus the fascism

Anyone ever tried super glue (cyanoacrylate) for mounting coverslips with stained mammalian cells, to be used for fluorescence microscopy?
I'm looking for ways to conserve microscopy samples for a looooooong time...

One week left to apply!

an infinity symbol with a snake in the middle Alt: an infinity symbol with an Ourobouros snake in the middle

Lustigerweise werden unsere Daten auch von Verlagen benutzt um zu zeigen, wie verbreitet die Forschung bei denen ist - ganz bestimmt hilft das beim anlocken von neuen Autor:innen auch.

Open Access: Der Preis für freie Wissenschaft Wenn Universitäten ihre Forschungsergebnisse kostenfrei zugänglich machen, müssen sie meist tausende Euro pro Artikel zahlen. So fließt Steuergeld an private Verlage, die große Gewinne machen. Das Pro...

Von wegen freies Wissen: Unis zahlen tausende Euro pro Artikel, um Forschungsergebnisse – oft mit Steuergeldern finanziert – frei zugänglich zu machen. Doch die Transparenz hat einen hohen Preis: Private Verlage machen damit ein undurchsichtiges Milliardengeschäft. fragdenstaat.de/artikel/exkl...

... nicht viel Sachliches zu den Artikeln hinzufügen und die Verlage dafür auf unbezahlte Reviewer zurückfällt. Auch das Argument der Werbung zieht wenig, da man Dank @altmetric.com gut zurück verfolgen kann woher das Engagement eigentlich kommt.

Vom Artikel: "Der Verlag Springer Nature erklärt auf Nachfrage, der Preis spiegele die Kosten für Begutachtung, Verbesserung und Veröffentlichung wider. Außerdem bewerbe der Verlag die Artikel und sorge dafür, dass sie auffindbar seien." Wenig daran ergibt viel Sinn, da Editoren meist...