JAC-AMR

Patients suffering from recurrent C. difficile infection in Sweden described their perceptions about the cause of their disease: antibiotics
They also described a scarce information process in a healthcare system without proper resources
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Nasomsong et al. conducted an observational study to evaluate the efficacy of high-dose tigecycline for carbapenem-resistant Enterobacterales bacteraemia: it was associated with improved microbiological clearance & showed a trend toward reduced mortality
doi.org/10.1093/jaca...
#IDSky

Predominance of ST772 ‘Bengal Bay’ MRSA causing human infections in Nigeria
Enhanced genomic surveillance and coordinated intervention strategies in LMICs are essential to address the growing threat of MRSA and its impact on public health
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Mori et al. found substantial knowledge gaps among non-infectious diseases physicians regarding bacterial bloodstream infection management:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky @bsacandjac.bsky.social

This systematic review highlights gaps in health and social care professionals’ knowledge, attitudes, and practices on infection management, antimicrobial use and stewardship, emphasizing the need for targeted interventions:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Wong et al. report prevalence of MG infection and resistance in MSM with HIV:
doi.org/10.1093/jaca...:
#JACAMRNews #IDSky

ESCMID’s 2-year Antimicrobial Stewardship (AMS) Certificate Program works!
65% of participants performed a project with real-world impact in #AntimicrobialStewardship:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Summary table showing the characteristics of the 7 resources reviewed. Citation: Figure 2 from https://doi.org/10.1093/jacamr/dlaf154 (CC-BY-NC 4.0)

A literature search identified 7 published resources on AMS undergraduate healthcare professional curricula or competency frameworks (CF) & compared with the WHO CF
Domains varied but significant overlap in WHO competencies in all 7
doi.org/10.1093/jaca...
#IDSky @bsacandjac.bsky.social

Blood Culture Pathway Modules - Infection Learning Hub These modules has been developed by NHS colleagues in collaboration with BSAC. They explore the role you play ...

Free NHS eLearning with BSAC: Optimising the Blood Culture Pathway. Practical, role-specific training to improve outcomes, speed diagnosis & support antimicrobial stewardship.
Start learning today. infectionlearninghub.co.uk/blood-cultur...

Is there scope for #AntimicrobialStewardship interventions in community pharmacy? Read on to explore where we are at and where we can go!
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Pharmacists’ access to clinical data and collaboration with healthcare providers are crucial steps to improve #AntimicrobialStewardship implementation in community settings
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

📝 Call for abstracts is open for #ACC2026!

Researchers are invited to share their work on #AMR for short talks or poster presentations.

💡 Themes: child & maternal health, stewardship & access, clinical research, AI in health & more.

⏳ Deadline: 14 Nov 2025, 17:00 GMT
🔗 acc-conference.com#posters

This study shows that more isolates of Escherichia coli, Klebsiella pneumoniae and other Enterobacterales are susceptible to amoxicillin/clavulanate than ampicillin/sulbactam:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Social determinants of health impact the risk of antimicrobial resistance
It’s time to refocus the research lens for knowledge, attitude and practice studies in AMR and prioritize change to address the upstream determinants:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Interdisciplinary approach to blood culture result management linked to decrease in mortality in community-onset S. aureus infections:
doi.org/10.1093/jaca...
@kasic.bsky.social #JACAMRNews #IDSky

Antibiogram showing the resistance profiles of the wound isolate (panel a) and intra-operative isolate (panel b) of NDM-producing Klebsiella pneumoniae complex according to CLSI and EUCAST interpretations for a range of antimicrobial agents, as described in Galfo et al., AMRrounds: susceptibility to the new tetracycline-derivative eravacycline of New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae complex, JAC-Antimicrobial Resistance, Volume 7, Issue 4, August 2025, dlaf153, https://doi.org/10.1093/jacamr/dlaf153

Eravacycline: a further weapon against NDM-producing Klebsiella pneumoniae? The case of a man with surgical site infection successfully treated with eravacycline plus ceftazidime/avibactam plus aztreonam
doi.org/10.1093/jaca...
#JACAMRNews #IDSky #AMRrounds @wwrighid.bsky.social

Check out this new #SAFEAMR study published in @jac-amr.bsky.social, which examines how antimicrobial resistance #AMR is framed in global policy, and the importance of clear, targeted messaging to drive action across all sectors.

📎 Publication: bit.ly/42ekH0Z

Study of differences in the intestinal microbiome & resistome among high-risk patients who are & are not colonized with CRE found statistically significant changes in the resistome
Longitudinally shifts were associated with antibiotic exposure
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Prolonged IV antibiotics aren’t just a patient safety issue - they generate considerable CO₂e
#AMS is climate action
doi.org/10.1093/jaca...
#JACAMRNews #Stewardship #Sustainability #IDSky @saiedali.bsky.social

This single-centre, prospective, observational pharmacokinetic study showed administering 3 g of ampicillin/sulbactam every 3 h maintained sufficient plasma concentration among adult liver transplant recipients even with excessive bleeding:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

What is the optimal teicoplanin target for E. faecium bacteraemia? Yamaguchi et al. found a freeAUC24/MICEtest of ≥462 reduces treatment failure:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky #AMR #PKPD

Infection with antimicrobial-resistant organisms significantly worsens outcomes in cancer patients
A survey of oncologists offers data that could support the development of oncology-specific AMS strategies and training programs:
doi.org/10.1093/jaca...
#IDSky #JACAMRNews

First-in-human study of the bezothiazinone and DpRE1 inhibitor, BTZ-043, a novel anti-TB drug candidate
Single ascending doses of BTZ-043 administered to healthy participants showed a good safety profile and favourable PK properties:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Fluoroquinolone use in France dropped over the past decade amid efforts to curb resistance and side effects, but continued efforts are needed to promote safe use:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky #AntibioticStewardship #Fluoroquinolones #DrugUtilisation #France

Meštrović et al. present a comprehensive set of pre-COVID-19 AMR burden estimates (deaths & DALYs) for Germany for 23 bacterial pathogens & 88 pathogen-drug combinations, and pursue comparative analysis with previous estimates
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Validate User AbstractBackground. Penicillin allergy (penA) records are common, but true penA is rare. PenA records are associated with broad spectrum antibiotic prescri

This paper explores patients’ views of their experiences of penicillin allergy de-labelling. Their insights will be used to further optimize penicillin allergy de-labelling implementation interventions:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

New research by @evakrockow.bsky.social et al. finds #AMR messages too technical and unclear
We need clearer, more relatable comms to drive change:
doi.org/10.1093/jaca...
@evakrockow.bsky.social @bsacandjac.bsky.social #JACAMRNews #IDSky

FI-Lab is a predictor of mortality in CDI patients and a valuable tool for early risk stratification:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky

Genomic and phenotypic analysis reveals high antimicrobial resistance in A. baumannii from combat wounds in Ukraine, posing treatment challenges:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky @bsacandjac.bsky.social

Genome report of MDR and ESBL-producing Shigella flexneri from Japan highlights antimicrobial resistance and virulence genes:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky