Sam Workenhe, DVM, PhD

Proud to share our work now out in Cell. We hope what we learned about IgA immune responses to rotavirus can be translated into better vaccines. Congratulations Dr. Kei Haniuda, an amazing PDF. TY
@uoftmedicine.bsky.social
for covering.

temertymedicine.utoronto.ca/news

SIGLEC12 mediates plasma membrane rupture during necroptotic cell death - Nature CRISPR–Cas9-based genome-wide screening shows that SIGLEC12 mediates plasma membrane rupture in cells undergoing necroptosis, possibly through a human-specific mechanism, indicating its potential as a...

This week is particularly remarkable in terms of #CellDeath and infection biology-related discoveries: biomed.news/bims-cediti/...
Highlight 1: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death:

Fascinating as always @reisesousalab.bsky.social &co! 1 aminoacid makes the difference between a CLR that drives cross-presentation or immune activation!! Kudos to all authors of this cool paper! 👇👇👇

🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...

Are you a recent PhD interested in a postdoc in Canada? Up to 20% of NSERC Postdoc Fellowships (70k/y for 2y) will be awarded to International applicants, who did their PhD outside of Canada. Deadline is 17 October. See: www.nserc-crsng.gc.ca/Students-Etu...

YouTube video by Dawn Bowdish The Perils of Being Born in the Fall at the Toronto Fringe 2025

Hey Toronto! It's 1 week until the #TorontoFringe and the first performance of "The Perils of Being Born in the Fall" on July 2nd. Tickets are as low as $4 for a full hour of 'edu-tainment' by your friendly neighbourhood scientist. Details & tickets at this link..
fringetoronto.com/fringe/show/...

Harvard steps up

www.harvard.edu/research-fun...

TBK1 and IKKε prevent premature cell death by limiting the activity of both RIPK1 and NLRP3 death pathways TBK1 and IKKe prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.

The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...

Pass it on.
#StandWithUkraine

Do you know (or are you) a senior scientist in the USA who might like to move to Canada in the near future? The 2026 call for CERCs (Canada Excellence Research Chairs) was posted last month: 🧪 ⚛️ 🔭 🇨🇦

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...

Every panel i ever participated in

C. elegans neuroscientist in a neuroscience startup pack

thank you for bringing back the fun of sci comm