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10.02.2024 15:08 — 👍 29786    🔁 2157    💬 924    📌 475

Food allergy: begin at the skin, end at the mast cell? - Nature Reviews Immunology In this Review the authors explain how different routes of exposure to food antigens can contribute to the development of food allergies. They discuss how allergic sensitization occurs against food antigens and focus on how IgE and mast cells ultimately drive the allergic pathology.

Food allergies may start with skin reactions, which reshape gut immunity and drive mast cell activation during subsequent exposures.

by Lukacs NW and Hogan SP in Nat Rev Immunol #MedSky

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10.11.2025 10:38 — 👍 14    🔁 6    💬 1    📌 0

COVID-19 is spreading again — how serious is it and what are the symptoms? Limited COVID-19 surveillance data are hampering vaccination and health strategies, researchers say.

Anecdotally people are presenting sicker as well. I wonder how much of this is attributable to much lower vaccination coverage rates than during the peak of the pandemic. Adult uptake in the US stalled at 21% last year. I predict it will be lower this year.
www.nature.com/articles/d41...

04.11.2025 17:22 — 👍 55    🔁 20    💬 4    📌 0

Genome-wide consensus transcriptional signatures identify synaptic pruning linking Alzheimer’s disease and epilepsy - Molecular Psychiatry No description

Microglial synaptic pruning connects Alzheimer’s disease and epilepsy, uncovering a potential therapeutic target for their comorbidity.

by Li H, Xie Z (...) Ji X et 13 al. in Mol Psychiatry #MedSky

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04.11.2025 08:41 — 👍 11    🔁 6    💬 0    📌 0

31.10.2025 06:37 — 👍 119    🔁 26    💬 4    📌 1

🌍 Today is World Evidence-Based Healthcare Day! 🩺💙

Every year on October 20, healthcare professionals around the world come together to celebrate and reflect on the importance of evidence-based practice the foundation of safe, effective, and high-quality care.

20.10.2025 09:38 — 👍 1    🔁 0    💬 0    📌 0

Genomically matched therapy in advanced solid tumors: the randomized phase 2 ROME trial - Nature Medicine In the proof-of-concept phase 2 ROME trial, comprehensive genomic profiling followed by molecular tumor board evaluation and randomization of patients with metastatic solid cancer to receive personalized therapy or standard of care led to a significantly higher objective response rate and longer progression-free survival in patients who received personalized therapy.

Genomically matched therapies boost response rates and progression-free survival in advanced solid tumors compared to standard treatments, ROME trial shows.

by Marchetti P, Curigliano G (...) Botticelli A et 43 al. in Nat Med #MedSky

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08.10.2025 14:34 — 👍 2    🔁 2    💬 0    📌 0

Full-spectrum extract from Cannabis sativa DKJ127 for chronic low back pain: a phase 3 randomized placebo-controlled trial - Nature Medicine A phase 3 trial found that VER-01, a full-spectrum cannabis extract, reduces chronic low back pain, improves physical function and sleep and shows no signs of dependence or withdrawal.

Cannabis extract VER-01 significantly alleviates chronic low back pain, demonstrating sustained effects and good tolerance in a phase 3 trial.

by Karst M, Meissner W (...) Häuser W et 3 al. in Nat Med #MedSky

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08.10.2025 16:36 — 👍 12    🔁 7    💬 0    📌 1

Huntington's disease successfully treated for first time - BBC News One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

Breakthroughs like this remind you why science matters, not for headlines, but for the families who’ve been waiting their whole lives to hear this.

Nb: it's not peer reviewed yet, but it's promising news

www.bbc.com/news/article...

24.09.2025 19:18 — 👍 1    🔁 0    💬 0    📌 0

Man critically injured after wearing metallic chain into MRI suite Reports indicate that the 61-year-old male entered the room while an exam was being performed on a patient.

healthimaging.com/topics/medic...

19.07.2025 03:01 — 👍 1    🔁 0    💬 0    📌 0

Voorbeeld 85833949 van institutioneel racisme Maakt levens kapot

20.06.2025 04:15 — 👍 53    🔁 18    💬 2    📌 3

FDA will limit Covid vaccines to people over 65 or at high risk of serious illness, leaders say The FDA announced it will limit access to Covid-19 vaccines going forward to people 65 and older and others at high risk of serious illness

GUYS. The comment period for this ends in THREE DAYS. PLEASE if you have even a little bit of time, submit a comment here: www.regulations.gov/commenton/FD...

Let them know EVERYONE should be able to get COVID vaccines. They BACK DOWN when WE PUSH BACK. www.statnews.com/2025/05/20/f...

20.05.2025 19:36 — 👍 6862    🔁 6531    💬 547    📌 588