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Kelly Sheppard (he/him/his)

@kstrna62.bsky.social

Spouse, parent, home cook, educator, cynical optimist, tRNA biochemist at a small liberal arts college, collaborative research w/ undergrads, flipped classroom, CUREs, assessment, pre-health advising, Californian living in upstate NY via CT

484 Followers  |  1,172 Following  |  526 Posts  |  Joined: 07.02.2024
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Posts by Kelly Sheppard (he/him/his) (@kstrna62.bsky.social)

Do wonder about how the clustering is done. Life Science Supercluster seems far from the Chemistry Research Cluster.
bluesky-map.theo.io

05.03.2026 13:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

As a biochemist, shouldn't the Chemistry cluster be closer to the Life Science Supercluster?

05.03.2026 13:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Supporting the NIH fellows union. Which legally speaking DOES still exist. Regardless what the administration tries to claim.

04.03.2026 23:51 β€” πŸ‘ 74    πŸ” 32    πŸ’¬ 3    πŸ“Œ 1

Lou Holtz was fired as head coach at Arkansas because he kept taping campaign ads for Jesse Helms.

He was too racist for Arkansas. In 1983.

04.03.2026 21:41 β€” πŸ‘ 1753    πŸ” 449    πŸ’¬ 47    πŸ“Œ 22

As a professor, providing accommodations doesn’t impact me at all, and it helps students out. The fact that anyone cares about this is baffling to me.

But then I remember that the country is currently run by eugenicist freaks and they’ve just found a new group to hound.

04.03.2026 22:05 β€” πŸ‘ 456    πŸ” 113    πŸ’¬ 12    πŸ“Œ 1

Horrific and extremely hard to read

Every Democratic presidential candidate should read it

03.03.2026 20:04 β€” πŸ‘ 16    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0

The hydrogen donor and acceptor possibilities with a decent hydrocarbon chain. It is the amidated form of glutamic acid and named accordingly.

03.03.2026 19:51 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

1) glutaminyl-tRNA synthetase in eukaryotes and some bacteria and the amidotransferases 2)GatCAB in most bacteria and 3) GatDE in archaea. Glutaminyl-tRNA synthetase evolved after the split in the last universal common ancestor of modern life, likely in an early eukaryote.

03.03.2026 19:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Partial to glutamine - which can be cyclized to form 5-oxo-proline and ammonia. Three different enzymes have evolved to to prepare it for protein synthesis (form glutaminyl-tRNA).

03.03.2026 19:36 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

How were the indirects accounted for? Related, when I was at Yale, every few years someone wanted to cut the stockroom as an expense. However, it saved more money than it cost. The cost was to one budget line but the savings were spread over multiple ones. Dangers of being overly reductionist.

02.03.2026 16:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

It says more Neanderthal males had children with modern human females than the Neanderthal females with modern human males. It doesn't say anything about attraction. A big point of the thread is that we can NOT get at attraction and other aspects of behavioral, social, & cultural reasons as to why.

27.02.2026 14:02 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

First - Jessica Williams is so talented - she knocks it out of the park on Shrinking. Harrison Ford is also a joy on screen.

Second - yes, very happy to get a double dip of Bill Lawrence tonight, Shrinking and Scrubs!

26.02.2026 01:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Doesn't he use a negotiations to sit out of camp, which he doesn't need and likely adds wear and tear on his body (cost to benefit is not there)? Doesn't it also provide cover to the 49ers why he isn't participating?

25.02.2026 16:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

Racism and ableism are truly toxic. The BBC & the BAFTA Awards set Davidson up to fail, and Black actors and audience members bore the brunt of it. Rather than supporting people, the BBC & BAFTA made choices that increased the likelihood of harm.

25.02.2026 16:04 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Yes, it is messy, nuanced, complicated, and challenging to do so, but that is the nature of science, of learning.

If we hide behind neutrality, how can expect our students to embrace the possibility of failure? Of challenges? Of being wrong?

25.02.2026 15:22 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We are humble to know that we will fail and will learn from that failure.

Pushing for neutrality as a guiding principle takes away from that. We can't play it safe. We do our best and embrace the possibility of failure.

25.02.2026 15:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

What we do in science is to be curious and systematic in trying to understand our world better by to the best of our abilities overcome our biases (individual, cultural, and systematic). We do so at the individual and group levels as well as across generations.

25.02.2026 15:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I would add, at least in my mind, that we do not try to be political, apolitical, partisan, bipartisan, nonpartisan, etc. in science. Trying not to be political/partisan is a bias. Neutrality is not what we are trying to accomplish. Science is a human enterprise; we cannot forget our humanity.

25.02.2026 15:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Read the whole thread, too.

22.02.2026 20:55 β€” πŸ‘ 14    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Preview
Will self-driving β€˜robot labs’ replace biologists? Paper sparks debate AI-driven autonomous robots are coming to biology laboratories, but researchers insist that human skills remain essential.

A single grad student achieves 600% improvement in 4 months, then an entire lavishly funded team achieves a further 40% improvement in 6 months.

Nature says the latter has "eclipsed" the former.

This is so dumb.

www.nature.com/articles/d41...

22.02.2026 20:04 β€” πŸ‘ 50    πŸ” 16    πŸ’¬ 5    πŸ“Œ 2
Preview
Grievance Is All You Need Understanding attacks on NIH, CDC and FDA through the lens of COVID revisionists

Read this!

2/2

joshuasweitz.substack.com/p/grievance-...

22.02.2026 14:23 β€” πŸ‘ 18    πŸ” 7    πŸ’¬ 0    πŸ“Œ 2

Yesterday @joshuasweitz.bsky.social wrote the best essay I’ve seen on Covid revisionism

The MAGA & MAHA extremistsβ€”eg RFK Jr & Drs Bhattacharya, Kulldorff, Atlas & Makaryβ€”keep saying the pandemic wasn’t that bad, life saving public health protections weren’t needed, & the vaccine was dangerous
1/2

22.02.2026 14:23 β€” πŸ‘ 32    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1
But, throughout this, I cannot think of a single example of what would be described as a "replication study". There is also not a single example of a p-value in any of these papers. Statistical hypothesis testing is just not part of how this science moves forward. This is another example of why John Ioannidis's famous paper "Why Most Published Research Findings are False" is itself almost certainly false.

But, throughout this, I cannot think of a single example of what would be described as a "replication study". There is also not a single example of a p-value in any of these papers. Statistical hypothesis testing is just not part of how this science moves forward. This is another example of why John Ioannidis's famous paper "Why Most Published Research Findings are False" is itself almost certainly false.

4/5

21.02.2026 17:12 β€” πŸ‘ 29    πŸ” 6    πŸ’¬ 1    πŸ“Œ 2

Less than 1 year. That’s all it took for many universities to collapse on themselves & wipe away many offices, programs, & positions that expanded knowledge, opportunity, & support for communities excluded from or tokenized on their campuses; to increase restrictions on student agency & voice. 1/4

19.02.2026 13:21 β€” πŸ‘ 46    πŸ” 20    πŸ’¬ 2    πŸ“Œ 0

May want to check out the ACLU.
bsky.app/profile/aclu...

19.02.2026 13:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@acs.org Any updates you want to share?

19.02.2026 13:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

At some point do us academic chemists need to leave and form our own society? The cost of ACS journal access compared to other disciplines is bananas and the same for national meetings. They don't appear to be standing up to power.

19.02.2026 13:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

To add "Under his leadership, [ACS] CAS collaborates with global R&D organizations to integrate curated scientific content with advanced technologies, including AI, driving innovation that improves lives."

19.02.2026 11:24 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Translating perfectly - Also,"He is deeply committed to empowering others to achieve individual professional and personal success." Can't wait for his self-help book & videos.

19.02.2026 11:23 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Basically, the Executive Leadership of ACS is not aligned with academic chemists to advance chemistry and chemistry education. www.acs.org/about/leader...

19.02.2026 00:33 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0