Vibhu Prasad

The question of the origin of #SARS-CoV-2 is a matter of significant scientific and public interest. Current publicly available data suggests a natural origin, while evidence supporting a lab origin remains scarce. Although no hypothesis has been definitively proven, the available data indicate...

09.04.2025 12:05 — 👍 36    🔁 10    💬 3    📌 0

‼BREAKING‼
We’ve secured new funding for the Boston Bioimage Analysis Course (BoBiAC) this July at Harvard Med School! Course fees down 37%, with fee waivers for academic applicants, for an intensive hands-on intro to bioimage analysis with Python!

Apply by June 1st!
iac.hms.harvard.edu/bobiac/2025

22.04.2025 14:55 — 👍 19    🔁 12    💬 0    📌 2

Importin-9 and a TPR domain protein MpH drive periodic patterning of ciliary arrays in #Tetrahymena, say Anushi Suwaneththiya Deraniyagala, Wolfgang Maier, Jacek Gaertig @universityofga.bsky.social and colleagues: rupress.org/jcb/article/...

#Cilia #Development

04.04.2025 14:29 — 👍 9    🔁 3    💬 0    📌 0

Transmission of unfolded protein response—a regulator of disease progression, severity, and spread in virus infections | mBio The unfolded protein response (UPR) is a cellular stress response pathway activated by the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum (ER) (1). The UPR aims to restore...

ER stress in cells (cell-autonomous) can be transmitted to neighbouring unstressed cells to generate a broader systemic ER stress response (cell non-autonomous ER stress) and hence have a wider impact in an organism where the stress was initially induced. Its significance to virus infections! 👇🏽

08.01.2025 21:21 — 👍 4    🔁 1    💬 0    📌 0

Endothelial inflammation in COVID-19 Disrupted endothelial function underlies the multiorgan complications of COVID-19

Infection with #SARSCoV2 has highlighted how altered endothelial functions contribute to multiorgan health effects during the acute phase of #COVID19 and potentially to the longer-term consequences associated with #LongCovid.

Learn more in a new #SciencePerspective:

17.12.2024 19:45 — 👍 75    🔁 23    💬 3    📌 3

We focused on a biological process shared between the 2 tissues: the unfolded protein response (UPR). Both tissues become highly secretory but make different cargoes. Cells activated the UPR prior to cargo production, suggesting developmental anticipation of future stress. (5/)

26.11.2024 15:49 — 👍 2    🔁 1    💬 1    📌 0

Poster of key discoveries in virology, starting in 1796

Viruses are therefore important: they affect all life on earth. They themselves also change, as we now notice with #SARSCoV2 who has made the leap to humans. Viruses can sometimes even determine what will survive. Don't underestimate these little bundles of information.

09.12.2024 19:25 — 👍 37    🔁 4    💬 6    📌 1

Regulatory interactions between APOBEC3B N- and C-terminal domains biorxiv.org/cgi/content/short/2024.12.11.628032v1

13.12.2024 10:53 — 👍 1    🔁 1    💬 0    📌 0

Submit your research abstracts for the 34rd Annual Meeting of the Society for Virology before it's too late. You only have a little more than a week left! Deadline is 1 December!

🔗 virology-meeting.de/registration...

#GfV #GfV2025 #virology #virologymeeting #virus #viruses

24.11.2024 15:06 — 👍 24    🔁 14    💬 0    📌 1