Uli Rass's Avatar

Uli Rass

@u-rass.bsky.social

I do my science at the Genome Damage and Stability Centre at the University of Sussex in sunny Brighton.

63 Followers  |  57 Following  |  12 Posts  |  Joined: 03.09.2025  |  2.1713

Latest posts by u-rass.bsky.social on Bluesky

Separate photos of Yara Zebian, Shaunna McIvor and Joao M. Uratani.

Separate photos of Yara Zebian, Shaunna McIvor and Joao M. Uratani.

Wanna find out more about this year's new Hive Scholars? πŸ‘€

Meet Yara Zebian, Shaunna McIvor and Joao M. Uratani. Discover how they will support Sussex's PGR research culture and what they are currently researching.

tinyurl.com/mv9j7hkm

06.10.2025 14:30 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Preview
DNA circuits store data β€” with heat as their power source Nature - DNA computers can use biological material to perform mathematical functions and store information, but their power sources have been fragile. Researchers now say they’ve developed a...

DNA computers could one day be used to store data, solve difficult mathematical problems and analyse biological data

go.nature.com/46C1hpH

04.10.2025 15:35 β€” πŸ‘ 33    πŸ” 11    πŸ’¬ 1    πŸ“Œ 1

In memory of Jane Goodall, English primatologist and anthropologist and the world's foremost expert on chimpanzees. Take a look at her 1985 article published in #PhilTransB 'Conditions of innovative behaviour in primates': royalsocietypublishing.org/doi/10.1098/...

02.10.2025 07:34 β€” πŸ‘ 61    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0
Post image

Join Francis Crick Prize winner Professor Sam Behjati for this free upcoming lecture on 10 October, as he discusses insights into the early detection and prevention of childhood cancer: https://royalsociety.org/science-events-and-lectures/2025/10/francis-crick-prize/

02.10.2025 09:31 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Preview
Jane Goodall’s legacy: three ways she changed science The primatologist challenged what it meant to be a scientist.

Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91

go.nature.com/46K10ja

02.10.2025 09:38 β€” πŸ‘ 139    πŸ” 45    πŸ’¬ 3    πŸ“Œ 4
Video thumbnail

Do you want to raise the profile of your research, and share it with over 10,000 members of the public? The call for proposals to exhibit at the 2026 #SummerScience Exhibition is still open: https://royalsociety.org/science-events-and-lectures/summer-science-exhibition/call-for-proposals-2026/

28.09.2025 10:26 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Preview
The future of universities: A Nature special report The world's universities are under intense pressure. Nature examines the threats they face and asks how the sector can and must adapt to survive.

A Nature special: Universities made the modern world. Now they must survive it.

go.nature.com/4nTooBX

24.09.2025 17:01 β€” πŸ‘ 24    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1
Preview
Huntington’s disease treated successfully for first time in gene therapy trial UCL trialled hours-long surgical procedure to treat disease which causes dementia and paralysis Huntington’s disease, a devastating degenerative illness that runs in families, has been treated successfully for the first time in a breakthrough gene therapy trial. The disease, caused by a single gene defect, steadily kills brain cells leading to dementia, paralysis and ultimately death. Those with a parent with Huntington’s have a 50% chance of developing the disease, which until now has been incurable. Continue reading...

Huntington’s disease treated successfully for first time in gene therapy trial

24.09.2025 14:05 β€” πŸ‘ 462    πŸ” 134    πŸ’¬ 15    πŸ“Œ 21
Post image

Professor Gillian Bates FRS, who co-founded the Huntington's Disease Centre with Professor Tabrizi, is delivering the Ferrier Prize Lecture on her work unraveling the molecular basis of this disease on 6 October. You can register below:

royalsociety.org/science-even...

24.09.2025 15:09 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Our Co-Directors Prof @chrispepper68.bsky.social and Dr @rhysmorganlab.bsky.social explain the mission and vision for the Sussex Blood Cancer Research network.

@sussexcancer.org @bsmsmedschool.bsky.social @biochembiomeduos.bsky.social

23.09.2025 16:17 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Preview
CRISPR activation for SCN2A-related neurodevelopmental disorders - Nature Using SCN2A haploinsufficiency as a proof-of-concept, upregulation of the existing functional gene copy through CRISPR activation was able to rescue neurological-associated phenotypes in Scn2a haploinsufficient miceΒ and human neurons.

Nature research paper: CRISPR activation for SCN2A-related neurodevelopmental disorders

go.nature.com/3VmV1vp

24.09.2025 07:34 β€” πŸ‘ 23    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Preview
UK is β€˜worst country in Europe’ for drug prices, says Mounjaro maker Eli Lilly CEO says Britain’s strict regime means it could miss out on new drugs being rolled out unless it pays more * Business live – latest updates The chief executive of the pharmaceutical company Eli Lilly has said the UK is β€œprobably the worst country in Europe” for drug prices, amid a row between the industry and government. Dave Ricks said that the UK’s strict pricing regime, allowing it to pay less for drugs than other developed countries, means it would miss out on new drugs being rolled out if it did not raise prices and scrap a rebate scheme. Continue reading...

UK is β€˜worst country in Europe’ for drug prices, says Mounjaro maker

24.09.2025 07:47 β€” πŸ‘ 53    πŸ” 8    πŸ’¬ 23    πŸ“Œ 16
Post image

Are you a biologist with a research interest in embryogenesis or synthetic biology?
Join our upcoming residential scientific meeting in Brighton on 20-21 October on the topic of generative biology: royalsociety.org/science-even...

24.09.2025 09:06 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image

Join Francis Crick Prize winner Professor Sam Behjati for this free upcoming lecture on 10 October, as he discusses insights into the early detection and prevention of childhood cancer: https://royalsociety.org/science-events-and-lectures/2025/10/francis-crick-prize/

23.09.2025 13:31 β€” πŸ‘ 0    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Preview
Journals infiltrated with β€˜copycat’ papers that can be written by AI Tools such as ChatGPT can be used to generate almost-identical research papers that pass standard plagiarism checks. Hundreds are thought to have been published.

Tools such as ChatGPT can be used to generate almost-identical research papers that pass standard plagiarism checks

go.nature.com/4pR5Wf0

23.09.2025 15:50 β€” πŸ‘ 24    πŸ” 11    πŸ’¬ 1    πŸ“Œ 1

Are you interested in working on related projects? 🌱
The Knipscheer lab at the Hubrecht Institute (Utrecht, the Netherlands) has openings for a postdoc and a PhD position.
Apply here: www.hubrecht.eu/jobs

19.09.2025 12:32 β€” πŸ‘ 13    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1

Is the animation available for download?

19.09.2025 16:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
PDTF - Homologous Recombination Defective Cancers ( Profs Chris Lord and Andrew Tutt) in Chelsea | The Institute of Cancer Research View details and apply for this PDTF - Homologous Recombination Defective Cancers ( Profs Chris Lord and Andrew Tutt) vacancy in Chelsea . Salary: Dependent on relevant Postdoctoral exp...

We're hiring ! Specifically....we are seeking to appoint a creative and motivated Postdoctoral Training Fellow to study how drug resistance emerges in homologous recombination defective (HRD) breast cancers and how this could be targeted. jobs.icr.ac.uk/vacancies/13...

19.09.2025 07:38 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Congrats K-P, beautiful!

19.09.2025 07:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Video thumbnail

Thrilled that our work is now finally out in Nature Comms!
rdcu.be/eG3vP

We reveal cryo-EM structures of the MRN complex bound to DNA & TRF2 - showing how DNA breaks are sensed and regulated at telomeres.
Fantastic work by first authors @yilanfan.bsky.social @filizkuybu.bsky.social & Hengjun!

18.09.2025 16:09 β€” πŸ‘ 70    πŸ” 21    πŸ’¬ 3    πŸ“Œ 4
Preview
Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.

Deadline 15th October. Get in touch if you have any questions.

Please repost!

More details:
www.imperial.ac.uk/jobs/search-...

18.09.2025 20:02 β€” πŸ‘ 29    πŸ” 35    πŸ’¬ 0    πŸ“Œ 3
Video thumbnail

There's still time to submit your proposal to exhibit your research at the #SummerScience Exhibition 2026! With the call for proposals open until 8 October, don't miss this unique opportunity to connect with the public, potential funders and government: royalsociety.org/science-even...

18.09.2025 11:45 β€” πŸ‘ 4    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Now out! Led by @susana-sousa.bsky.social and Noa Amin, and thanks to our collaborators in the Harrington @icr.ac.uk and Stucki and Choudhary @jc4-jyoti.bsky.social labs

www.cell.com/cell-reports...

16.09.2025 15:30 β€” πŸ‘ 14    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
Preview
Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication Genome inheritance during cell divisions relies on replicated sister DNAs being connected by cohesin rings. Minamino et al. reconstitute sister chromatid cohesion establishment during DNA replication using purified budding yeast proteins. The experiments yield molecular insight into more than one way in which sister chromatid cohesion can be built.

Online Now: Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication Online now:

16.09.2025 15:20 β€” πŸ‘ 9    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

congratulations to our DB colleague Maria Jasin, recognized by the Greengard Prize! when she started her lab @mskcancercenter.bsky.social, she was the first to insert DNA into a defined location of a mammalian genome! her work underlies today's CRISPR-mediated HDR. here in convo with Rick Lifton.🧬

17.09.2025 12:10 β€” πŸ‘ 22    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
Preview
Rethinking neurodegeneration: Could DNA repair hold the key to treating Huntington's disease? With Prof Sarah Tabrizi & Prof Prof Gabriel Balmus

Webinar: Could DNA repair hold the key to treating Huntingtons disease?🧬

Join UK DRI Group Leaders Profs Sarah Tabrizi & Gabriel Balmus as they dig into the latest discoveries and therapeutic breakthroughs from the field

πŸ—“οΈ Mon 29 Sep πŸ•“ 4-5pm (BST)

Register free πŸ‘‰ www.ukdri.ac.uk/events/rethi...

10.09.2025 16:41 β€” πŸ‘ 7    πŸ” 8    πŸ’¬ 0    πŸ“Œ 2
Post image

Naomi Datta FRS was born #OnThisDay in 1922. She discovered horizontal gene transfer, the passing of genetic material between organisms, as a key factor in the spread of antibiotic resistance in bacteria.

#WomenInSTEM

17.09.2025 10:53 β€” πŸ‘ 41    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
Preview
Do smartphones and social media really harm teens’ mental health? Researchers are debating the strength of evidence connecting technology to surging rates of adolescent mental illness. But they have some clear advice for parents.

How much are phones and social media to blame for mental health struggles in adolescence?

go.nature.com/4gmdbXL

15.09.2025 11:04 β€” πŸ‘ 26    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1
Preview
Feeling the heat: fossil-fuel producers linked to dozens of heatwaves Hear the biggest stories from the world of science | 10 September 2025

Latest from the Nature Podcast πŸ”Š Feeling the heat: fossil-fuel producers linked to dozens of heatwaves

go.nature.com/42hfxkY

13.09.2025 12:13 β€” πŸ‘ 35    πŸ” 14    πŸ’¬ 1    πŸ“Œ 2
Preview
AI-generated medical data can sidestep usual ethics review, universities say Representatives of four medical research centres have told Nature they have waived normal ethical review because 'synthetic' data do not contain real or traceable patient information.

Medical researchers at some institutions in Canada, the United States and Italy are using data created by AI from real patient information in their experiments without the need for permission from their institutional ethics boards

go.nature.com/42n8Cqj

12.09.2025 14:25 β€” πŸ‘ 13    πŸ” 6    πŸ’¬ 1    πŸ“Œ 5

@u-rass is following 20 prominent accounts