@chrishsiung.bsky.social
Molecular biologist | Assistant Professor at UCSF | hsiunglab.org | synthetic gene regulation, combinatorial genetics, tissue biology | #ClimateCrisis
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29.07.2025 01:08 — 👍 0 🔁 0 💬 0 📌 0
New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?
www.biorxiv.org/content/10.1...
we are very interested using our recently developed combinatorial Cas12a CRISPRi platform. happy to chat!
23.07.2025 00:16 — 👍 2 🔁 0 💬 1 📌 0EPIGENETIC HULK READY TO SMASH AGAIN! GET IN LOSERS!
13.06.2025 04:30 — 👍 158 🔁 47 💬 10 📌 10#FragileNucleosome seminar happening tomorrow!
03.06.2025 10:29 — 👍 4 🔁 6 💬 0 📌 0Looking forward to sharing our work in the #FragileNucleosome series!
03.06.2025 03:58 — 👍 0 🔁 0 💬 0 📌 0We're still recruiting!
09.05.2025 22:25 — 👍 0 🔁 0 💬 0 📌 0We've successfully recruited one postdoc. We are still looking to recruit one more postdoc especially candidates with wet/dry lab hybrid background in genome regulation and/or interests in functional genomics approaches in novel human tissue biology models.
13.03.2025 06:50 — 👍 0 🔁 1 💬 0 📌 1
Excited to share James Jusuf's preprint:
By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%)
We quantify mESC 36k loops: <loops> are generally rare (2.3%)
www.biorxiv.org/content/10.1...
Happy new year! Our lab (hsiunglab.org) at UCSF is moving forward to next stages in our search for postdoc candidates. The positions are still open -- if interested please apply soon!
06.01.2025 18:18 — 👍 4 🔁 0 💬 0 📌 0
A little fun with numbers on this Sunday, showing just how successful DNA really is. First, here's what DNA looks like. I'll draw your attention to the "rise" in DNA, that is, the distance between two basepairs, which is 3.4 Angstroms, also known as 3.4x10^-10 meters...
08.12.2024 21:52 — 👍 144 🔁 32 💬 4 📌 5Honored to be endorsed in your first post here!!
05.12.2024 01:38 — 👍 0 🔁 0 💬 0 📌 0Where appropriate there would be exceptional opportunities to work collaboratively with the help of junior specialists in the lab, as well as with other UCSF labs with complementary expertise.
30.11.2024 06:45 — 👍 0 🔁 0 💬 1 📌 0We esp. welcome individuals who add to our capabilities and perspectives in computation or specific biological domains in tissue biology.
30.11.2024 06:45 — 👍 0 🔁 0 💬 1 📌 0
My lab at UCSF (hsiunglab.org) is looking to recruit multiple postdocs across the spectrum of wet/dry lab interests to contribute to our research in synthetic gene regulation, combinatorial genetics, and tissue biology (including liver biology and immuno-oncology).
30.11.2024 06:45 — 👍 2 🔁 0 💬 2 📌 3
