Sylvie Lhoste

PINNACLE-I evaluated a Hertz contact intravascular lithotripsy system for moderately to severely calcified coronary lesions, demonstrating high clinical success and effective calcium modification with consistent stent expansion. #cardiosky

eurointervention.pcronline.com/article/hert...

Five-year outcomes with the early-generation Intrepid transapical TMVR system showed sustained MR elimination, stable haemodynamics, and maintained functional improvement among survivors, supporting its role in selected high-risk patients. #cardiosky
eurointervention.pcronline.com/article/five...

🔥NEW ISSUE OUT🔥
State-of-the-art on residual risk pharmacotherapy • Day-case PCI consensus • Aspirin discontinuation in ACS • 7-year COMPARE-ABSORB • PINNACLE-I • Novel TR spacer • PCR news & more.
#Cardiosky #PCI #StructuralHeart
eurointervention.pcronline.com/issue/volume...

Residual cardiovascular risk persists even after successful revascularisation.
This new review explores adjunctive pharmacological strategies—from lipid- and triglyceride-lowering to anti-inflammatory therapies—to improve long-term outcomes.
#Cardiosky

eurointervention.pcronline.com/article/adju...

This new expert review summarises ICE technology, the features of available probes, and expert perspectives on its use in guiding structural heart interventions. #cardiosky
Don't miss it!
eurointervention.pcronline.com/article/thre...

NAVULTRA registry: in patients with small aortic annuli, intra-annular Navitor and SAPIEN 3 Ultra showed comparable 1-year clinical outcomes. Navitor delivered superior haemodynamics with less PPM, but more mild PVL and PM implantation. #cardiosky

eurointervention.pcronline.com/article/intr...

In this large-scale retrospective study, LM patients with left dominance undergoing PCI were associated with a significantly higher risk of long-term adverse events, particularly for TVR. #cardiosky

eurointervention.pcronline.com/article/impa...

This review summarises coronary imaging for plaque phenotyping, event-related features, and serial-imaging trials assessing therapy effects on plaque progression/regression.
eurointervention.pcronline.com/article/adva...
#cardiosky #EijBestOf

New Issue🔥
Expert review on 3D intracardiac echo, structural heart updates in small aortic annuli, long-term outcomes in TMVR, and insights on LM PCI prognosis—plus technical tips (distal foot access, stuck TAVI retrieval) and more.
eurointervention.pcronline.com/issue/volume...
#cardiosky

How chasing a high-impact publication nearly broke me

When my paper was published in Science, others expected me to be happy.

www.science.org/content/arti...

Here’s a handy overview of @eurointervention.bsky.social State-of-the-Art collection for 2024-2025 #cardiosky

eurointervention.pcronline.com/pages/euroin...

This meta-analysis of randomised trials showed that TEER plus guideline-directed medical therapy reduces heart failure hospitalisations in patients with symptomatic functional mitral regurgitation, compared with medical therapy alone. #cardiosky

eurointervention.pcronline.com/article/tran...

"Predictors of long-term structural valve deterioration and failure after transcatheter aortic valve implantation" by T. Palmerini et al. #cardiosky #cardiomed #cardiotwitter

eurointervention.pcronline.com/article/pred...

In this prospective multicentre registry of symptomatic high-risk patients, transcatheter closure of PVL was associated with sustained clinical benefit at mid-term follow-up, particularly when early clinical success was achieved. #cardiosky

eurointervention.pcronline.com/article/medi...

After PFO closure, continuous implantable cardiac monitoring revealed a high incidence of atrial fibrillation.
Most episodes are asymptomatic and paroxysmal, with a significant proportion occurring beyond 30 days. #cardiosky

eurointervention.pcronline.com/article/atri...

Rare complication after TAVI: embolisation and delayed twisting of a balloon-expandable valve led to spinal hypoperfusion and paraplegia in a 78y-old patient. Prompt valve-in-valve implantation restored flow with full neurological recovery. #cardiosky
eurointervention.pcronline.com/article/para...

Women physicians are more likely to shoulder caregiving responsibilities, more likely to experience workplace inflexibility, and more likely to practice in fields requiring prolonged emotional labor. Yet they work within systems still designed around outdated assumptions of availability, endurance, and sacrifice. - Arthur Lazarus, MD, MBA

US physician attrition is rising, hitting women and rural doctors hardest.

Systemic pressures and not just burnout drive exits, threatening healthcare access, especially in already underserved areas.

Structural change is needed to sustain the workforce.

kevinmd.com/2026/01/...

#CardioSky

In STEMI with 3-vessel OCT imaging, long-term risk appears driven more by non-ruptured TCFA than by plaque rupture itself.
These data refine the concept of pancoronary vulnerability and may inform future risk stratification. #cardiosky

eurointervention.pcronline.com/article/long...

High-risk plaques are identifiable, but their clinical event rate remains low
Evidence from PROSPECT and PREVENT suggests that, under OMT, prophylactic PCI mainly prevents future revascularisationsupporting a cautious, wait-and-see approach.
#Cardiosky
eurointervention.pcronline.com/article/high...

REPEAT-QFR - FAVOR III Europe substudy

In-procedure QFR demonstrated moderate diagnostic accuracy and reproducibility, with performance influenced by angiographic and analysis quality. #cardiosky

eurointervention.pcronline.com/article/repe...

New State-of-the-Art in EuroIntervention: lesion stratification with intracoronary imaging, covering morphology-guided PCI, high-risk plaque assessment, and the emerging role of AI in integrated morphofunctional evaluation. #cardiosky
eurointervention.pcronline.com/article/lesi...

🔥New issue out today!
Expert review on endomyocardial biopsy, high-risk plaque interventions, non-culprit plaque rupture, non-invasive CMD assessment, QFR reproducibility, STEMI in large coronary arteries — and more.
eurointervention.pcronline.com/issue/volume...
#cardiosky #cardioEd #cardiotwitter

This expert review outlines when and how to perform endomyocardial biopsy in current practice, with a new Central Illustration offering a clear visual synthesis of patient selection, technique, and downstream clinical implications.
#cardiosky
eurointervention.pcronline.com/article/endo...

New AOP in EuroIntervention
Successful retrieval of a stuck TAVI device via the LV apex after balloon alignment failure, followed by transapical implantation.

eurointervention.pcronline.com/article/retr...

#cardiosky

In SORT OUT X, the dual-therapy CD34 antibody-covered COMBO stent showed higher target lesion failure vs the Orsiro sirolimus-eluting stent at 5 years, driven by early revascularisation, with similar outcomes beyond year 1.
eurointervention.pcronline.com/article/dual...
#cardiosky

📢 New in EuroIntervention: a comprehensive State-of-the-Art on transcatheter edge-to-edge repair (TEER) for secondary mitral regurgitation.
From evolving SMR phenotypes to trial data, device innovation, patient selection & 2025 guideline updates.
eurointervention.pcronline.com/article/tran...

In this large real-world cohort, annular calcium volume was independently associated with ACURATE neo/neo2 valve underexpansion, while post-dilatation reduced deformation risk.
#cardiosky
eurointervention.pcronline.com/article/pred...

🔥NEW JAA
Redo surgery or transcatheter valve-in-valve?
The SURVIV trial is the first randomized study comparing mitral valve-in-valve with redo surgical replacement for failed bioprosthetic valves, aiming to guide evidence-based care
#cardiosky
eurointervention.pcronline.com/article/tran...

🔥 NEW IN EIJ
Watchman FLX showed improved safety and performance compared with Watchman 2.5 in a large matched analysis. #LAAC #CardioTwitter
eurointervention.pcronline.com/article/pred...

Exercise-based invasive physiology reveals distinct CMD phenotypes in ANOCA, including impaired exercise-induced vasodilation despite normal pharmacological hyperaemia.
#ANOCA #CMD #CoronaryPhysiology #cardiosky
eurointervention.pcronline.com/article/phen...