JD Tamucci

Mitochondria-Targeted Peptides and Bilayer Composition Modulate Membrane Electroporation under Elevated Electrochemical Stress Several studies have used molecular dynamics (MD) simulations to examine the relationship between transmembrane potentials (ΔΨm) and electroporation; however, research on how this relationship present...

I’m a bit late on this but the final paper from my PhD is published.

It’s about membrane potentials, and how bilayer composition alter bilayer capacitance, passive ion transport, and membrane stability under high electrochemical stress.

Many thanks to Eric, Nathan, & Adam for their contributions!

YouTube video by SciShow How Space Awakens Sleeping Viruses

The new episode I wrote for @scishow.bsky.social just came out! It's about #viruses, the kind that lie dormant inside us, and what happens to those viruses when we go to #space.

... I came away feeling grateful about the progress but also surprised, a bit let down.

There's still SO MUCH we don't understand about migraine's molecular etiology—and that's a problem. Researchers can't rationally design new treatments w/o a target to shoot for.

So we used this episode...

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YouTube video by SciShow We Need Better Migraine Meds.

"I can feel a migraine coming on. I can barely work—and if I don't leave now, I'm not sure I'll make it home."

If you get migraines, this scene may be familiar, and if you don't, someone in your life probably does. Over 1 billion people get them, and yet, there's still a lot we don't know.

Why?

That’s super annoying ☹️

The tiny changes made to the ASL broadcast, like tracking TOI on screen, are fascinating.

And a strange tangential side effect of not having announcers talking is you can hear the on-ice chatter. In game 5, I heard "Hey! What socks are you wearing?"

This would be great idea for other major cities too. Are you selling in local bookstores?

start to finish—selecting an issue, identifying stakeholders, developing a proposal, and delivering a short pitch. Grateful to have learned from such a fun and thoughtful cohort, and proud of the work Angela Fenoglio, Max O'Connor, McKenna Parnes, and I put together in our final project.
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screenshot of the one-page summary of our policy pitch on how to protect renters from future wildfires in Oregon. Happy to share the PDF if you're interested :)

Our team’s pitch on protecting renters from wildfire risk in Oregon was selected as the winning project in the "Science Policy Training Skills" course I took with the National Science Policy Network. Over eight weeks, we explored the policy proposal process from ...
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YouTube video by SciShow This Is What Happens When Regular People Go To Space

The new @scishow.bsky.social episode I wrote just dropped!

In 2021, 4 regular people (not astronauts) spent 4 days in space. In the episode, I cover:
• Why they went
• How it changed their bodies
• Why civilian astronauts matter for Mars

Any weird rule changes you’d actually like to see in the NFL this year?

Admirable. I also imagine it helps to have a like-minded staff.

Aww no! That sucks!

🐦‍⬛🔬Bird Flu (H5N1) – what’s the deal? 🤔
@pardissabeti.bsky.social joined @scishow.bsky.social
to break it all down—its origins, where it stands today, and why it matters. 🦠🐦 Here’s a sneak peek! 👀 Want the full story? Head to the SciShow's YouTube channel: youtu.be/5CyVi4UzKxE?... 🎥✨

It’s equal parts interesting and unsettling. I hadn’t heard about this before Alex pitched the episode topic to me. And I’ve had it on my mind ever since

I placed the lab keurig in my acknowledgements section and called it an honorary first author on every paper.

... Alzheimer's, we should see an uptick in those diseases in the next 10 years or so.

And with continued funding into viral vaccines and treatments, maybe—just maybe, we'll be able to put these devastating diseases behind us.

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... whether these viruses cause Alzheimer's, but they certainly check a lot of the boxes scientists look for. And we might get clarity on this soon.

The world is reeling from #COVID-19, a pandemic caused by a virus. If severe viral infections really do cause diseases like
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... what these viruses do to our cells and how we might stop them.

And for #publichealth nerds, we structured the episode around Bradford Hill's criteria for #causality. These criteria help scientists decide whether X really causes Y.

Currently, we can't say for sure
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YouTube video by SciShow The Flu May Cause Alzheimer's

A @scishow.bsky.social episode I wrote just came out! It's about how #viruses (mono, flu, herpes) may cause #neurodegenerative diseases like Alzheimer's.

Those viruses are super common which isn't great 😬 But knowledge is power. In the episode, we talk about
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youtu.be/REbjjVAX8vE?...

I like it. I've been trying to think of a catchy way to capture why that's true though if you were to use it in a talk.

I've been juggling these two ideas in my head:
1) Biology is ever-changing
2) Good enough (to reproduce) is good enough

Wild ideas about how to change the NFL, from minute rule changes to conference realignment

Totally understand. I really enjoy the audio content you produce. It’s clean & practical. I can see how applying that to an audio prospect guide would be a big undertaking. But I hope that profit margin shifts somehow in the future.

Would you consider producing a companion audio version of the Prospect Guide?

I have the 2024 version and loved it, but I just learn better via audio. Translating the colored charts to an audio format would be hard, but if the audio was only sold as an “add-on,” we could still reference the PDF.

That 4th down was a close call & could’ve gone either way. What really irks me though is why we accept some calls falling to chance. Why don’t we always have multiple cameras exactly at the first down (sideline & aerial)? Why do we tolerate the lawless jungle that is a fumble-turned-dog pile?

. @scishow.bsky.social brings fun, fact-checked science videos to millions of viewers on YouTube for free. It’s an honor to be a small part of it, but this show can only operate if people donate.

For $25, you get a signed postcard & exclusive video (see Hank’s post)

Or you can donate $5+ here

Empty Country: Marian
Spirit of the beehive: Wake up
Nat Vazer: Higher Places
Hovvdy: True Love
Half waif: Big Dipper
Amen Dunes: Believe
Trace mountains: Lost in th country
Erin Rae: Gonna be strange
Sasami: Take care
Bedouine: Thirteen
Nap Eyes: Mixer
Y la bamba: Ojos del sol
Mabe Fratti: Oídos

Wet leg: Piece of shit
Tanukichan: This time
Friko: Crimson to chrome
Andy Shauf: Wasted on you, Firetruck
Really from: Try lingual
Greg Mendez: Maria
Haley Heynderickx: Foxglove, Seed of a seed
Big thief: Simulation swarm
Whitney: No Woman, FTA
Camp cope: The Opener, Keep Growing

Lol maybe this is an american English thing. How would you pronounce the contraction “they should’ve?” My pronunciation would sound a lot like “should of” with no pause between.

Frontiers | Saline nasal irrigation and gargling in COVID-19: a multidisciplinary review of effects on viral load, mucosal dynamics, and patient outcomes With unrelenting SARS-CoV-2 variants, additional COVID-19 mitigation strategies are needed. Oral and nasal saline irrigation (SI) is a traditional approach f...

Hope you feel better soon. Unsolicited comment you can ignore: There’s a small but growing body of research suggesting that nasal saline irrigation reduces transmission and severe COVID outcomes (e.g., hospitalization). Also, it’s essentially harmless if done properly.

doi.org/10.3389/fpub...