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Jonathan Wilde

@neurogtx.bsky.social

I make gene therapies for neurological disorders. Lover of synthesizers, coffee, biotech, and all things Philly sports.

123 Followers  |  217 Following  |  65 Posts  |  Joined: 04.12.2024  |  1.9305

Latest posts by neurogtx.bsky.social on Bluesky

The most troubling part about the bear picture might be that his fly is down.

14.11.2025 20:04 โ€” ๐Ÿ‘ 26    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Fitting because a CharBroil Pro Series is how he gets his signature skin tone and texture.

14.11.2025 19:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

a โ€œSpace Forceโ€, if you will

13.11.2025 14:27 โ€” ๐Ÿ‘ 11635    ๐Ÿ” 1810    ๐Ÿ’ฌ 238    ๐Ÿ“Œ 54
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The incredible power of a kidney transplant. Still canโ€™t believe this when I look at it. Not even 3 weeks out and I honestly canโ€™t remember the last time I felt this good. #nephsky

12.11.2025 19:02 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

James Bond: Highlander

11.11.2025 14:29 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

lol my alma mater is cursed

08.11.2025 20:28 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Sarepta: Enough, For God's Sake

Someday I will not have to write about Sarepta Therapeutics and their ineffective drugs that never should have been approved by the FDA in the first place.

This is not that day.

05.11.2025 13:33 โ€” ๐Ÿ‘ 47    ๐Ÿ” 13    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 5

Whenever I see one of these mega-funded companies fold I canโ€™t help but wonder what could have been had that massive raise been used to seed a bunch of promising startups at $5-$10 mil each.

04.11.2025 22:08 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Ghost of Yotei and then Arc Raiders at the end of the month.

21.10.2025 10:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Voucher Program | Donate a Kidney to a Family Member or Friend The National Kidney Registryโ€™s Voucher Program was created to overcome compatibility issues between donors and recipients, as well as to make the process more convenient for donors and allow the best ...

This is pretty cool. Can't believe I hadn't heard about it before.

www.kidneyregistry.com/for-donors/v...

16.10.2025 17:14 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Iโ€™m cool with anything that gets us closer to getting rid of Franklin.

04.10.2025 21:08 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Is it the missed holding call, the BS reversal, or the ensuing TD?

28.09.2025 01:57 โ€” ๐Ÿ‘ 6    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Itโ€™s a US Ryder Cup performance fitting of the current state of America.

27.09.2025 21:40 โ€” ๐Ÿ‘ 779    ๐Ÿ” 99    ๐Ÿ’ฌ 64    ๐Ÿ“Œ 9

Ahhhh yes, because nothing screams great bagels like VC funding.

24.09.2025 16:53 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
In truth, neither Congress nor the executive can claim to represent the undivided will of the American people. It is arguable whether such a thing even exists in the American system, as the public is not a single entity but an ever-shifting set of groups and interests. Congress represents the American people in their diverse and fractious unity, and the president represents a will of some of the people, briefly assembled for a fleeting purpose, to dissipate until it forms anew in the next election.

It is simply a conceptual error to think of democratic legitimacy as a grant embedded in a single person. Itโ€™s better to see it as a relationship between our political institutions and the publics they serve, each responsive to the other as they work together to do the business of government.

In truth, neither Congress nor the executive can claim to represent the undivided will of the American people. It is arguable whether such a thing even exists in the American system, as the public is not a single entity but an ever-shifting set of groups and interests. Congress represents the American people in their diverse and fractious unity, and the president represents a will of some of the people, briefly assembled for a fleeting purpose, to dissipate until it forms anew in the next election. It is simply a conceptual error to think of democratic legitimacy as a grant embedded in a single person. Itโ€™s better to see it as a relationship between our political institutions and the publics they serve, each responsive to the other as they work together to do the business of government.

24.09.2025 10:33 โ€” ๐Ÿ‘ 1252    ๐Ÿ” 188    ๐Ÿ’ฌ 20    ๐Ÿ“Œ 8
"So Do" Dennis reads a speech written by Charlie -Its Always Sunny In Philadelphia
YouTube video by Joe A "So Do" Dennis reads a speech written by Charlie -Its Always Sunny In Philadelphia

youtu.be/bWnmGq1hZdE?...

Weโ€™re here

22.09.2025 21:37 โ€” ๐Ÿ‘ 127    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

go to super bowl
lose offensive coordinator
promote from inside the org
suck
hire outside oc
go to super bowl
lose offensive coordinator
promote from inside the org
YOU ARE HERE

21.09.2025 18:05 โ€” ๐Ÿ‘ 176    ๐Ÿ” 37    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 5
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GLP-1RA Semaglutide Delays the Progression of ADPKD Through Regulation of Glycolysis, Mitochondria Function and Ketosis - PubMed Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease that is caused by mutations in PKD genes. Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are a class of medicati...

GLP1ra in ADPKD?

pubmed.ncbi.nlm.nih.gov/40815122/

18.09.2025 03:59 โ€” ๐Ÿ‘ 14    ๐Ÿ” 7    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

This game is insane!

14.09.2025 20:18 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

If there was an asteroid with 100% chance of hitting Earth speeding toward us Democratic leaders would choose to do nothing because theyโ€™d be scared that people may blame them if they tried some sort of Armageddon-style mission to save humanity and it went wrong.

07.09.2025 13:32 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

The one thing we can't have dudes getting paid millions to try to kill each other doing is flexing their muscles at each other. That's going a bit too far.

05.09.2025 01:23 โ€” ๐Ÿ‘ 9    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

LOL weโ€™re so back

05.09.2025 00:58 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Could not be a more Philly start to this title defense. ๐Ÿคฆ๐Ÿปโ€โ™‚๏ธ

05.09.2025 00:27 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Yeah, but have you seen his mailbag?

04.09.2025 14:42 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I was concerned that America doesnโ€™t have an out-of-shape actor to protect us now that Steven Seagal has gone 100% Russian, but it looks like I can sleep tight after all.

23.08.2025 17:56 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

It was brutal the other week when Hulk Hogan died and Roy had to sit there for 2 hours listening to everyoneโ€™s โ€œhe was a racist piece of shit and a terrible human but I still love himโ€ takes.

09.08.2025 15:16 โ€” ๐Ÿ‘ 8    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

The gardener wearing a shirt that says "GARDENER" is absolutely killing me.

05.08.2025 17:45 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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It takes a special kind of person to give part of yourself so someone else can live ๐Ÿงก Congratulations to Mohamed on getting your new kidney โ€” and thank you Julian for being a living donor hero.

23.07.2025 14:04 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Re $SRPT, huge doses are used, for Elevidys approx 10exp16 genomes for 70kg+, 100x > # of cells in the human body, or an MOI of 100 for every cell the patient has, ie trying to force AAV to do something it's not really capable of: Is it really surprising if tox issues may result?

19.07.2025 12:40 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

the people driving science into freefall arenโ€™t just malign, but also incurious and dull

fed lies & luxury, they never wrestled with nature or saw the beauty of its hidden truths โ€” much less discovered any

they lack the ability or desire to invent, to cure, to solve big problems facing humanity

15.07.2025 13:19 โ€” ๐Ÿ‘ 44    ๐Ÿ” 18    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2

@neurogtx is following 20 prominent accounts