Marine Laporte

#GEF25 Concluding Plenary Lecture with the wonderful Virginie Hamel.

The ExM gang @jvermot.bsky.social @mahjoublab.bsky.social @marinelap.bsky.social @centriolelab.bsky.social @simonemortal.bsky.social et al #GEF25

Now out on bioRxiv. 🥳My research on #cytokinesis, averaging thousands of #ExM images🔬, creating a dynamic atlas of cytokinesis 🦠⏳. Here's an animated sneak peek of what we found. Better resolution on bioRxiv😄 #PSFoftheGIF

Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...

#ExM turned 10 this year - just like #NanoTag! 🎉
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.

See you in Göttingen!
#GEF25

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

🚨
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.

▶️ www.biorxiv.org/content/10.1...

With a combination of FIB-SEM, super-resolution & expansion #microscopy, Araujo Alves, Bastin et al @bastinlab.bsky.social @pasteur.fr reveal how IFT trains are progressively restricted to a limited number of #microtubule doublets in the flagellum of T. brucei. rupress.org/jcb/article/...

#Cilia

⏰ One week countdown- 19/08/2025 15:00 BST we kick off our 52nd BSCB GenSoc UK Cilia and Centrosome Network e-symposium with 6 stellar talks from the field's rising stars 🌠 on the latest breaking science 🧪!!

FOMO? Join the fun: www.eventbrite.co.uk/e/bscb-genso...

PhD position in cell biology - Golgi apparatus and protein transport in muscle Institut NeuroMyoGene - PGNM, Lyon, France -Muscle Nuclear Cytoskeleton and Architecture

exoendo.org/en/offre-dem...

Publications scientifiques - Club Exo Endo - Exocytose Endocytose

Discover the new publications from the Club Exo-Endo teams!

exoendo.org/en/publis-sc...

GPR161 mechanosensitivity at the primary cilium drives neuronal saltatory migration Primary cilium senses mechanical cues to regulate young neuron migration via GPR161 signaling.

🎉Excited to see my master’s work contributed to this amazing paper! 🎥 🧠

Congrats to all co-authors 👏
Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨

doi.org/10.1126/scia...

Save the date!
March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳
Stay tuned for more info!

Attention #microtubule and #centrosome fans!!! Here's another fantastic #openaccess #research #article in #CYTOSKELETON. LZTS2 Negatively Regulates Centrosomal CEP135 Levels and Microtubule Nucleation. Check it out here: onlinelibrary.wiley.com/doi/full/10....

🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...

World Ocean Day graphic including colourful scientific images of ocean plankton

It's #WorldOceanDay – this year’s theme is: ‘Wonder: sustain what sustains us’. One key force sustaining ocean life is microbes. With @embl.org TREC we explored this hidden universe along Europe's coasts, across water, sediment and soil to see how microbial life connects across ecosystems and biomes

Ahaha this is excellent !

During #mitosis, before assembling the mitotic spindle, the early mouse embryo lacking #centrosomes uses #actin rather than #microtubules for chromosome congression 👀👇🏼

Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37 Nature Structural & Molecular Biology, Published online: 25 May 2025; doi:10.1038/s41594-025-01540-6Here Yeow et al. present a model in which TRIM37 regulates microtubule-organizing centers through substrate-templated activation, providing a unifying mechanism for the control of mesoscale assemblies by the TRIM family of E3 ligases.

New online: Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37

Nice cool study, @syncellbiolab, @anubhav_dhar, @SuchetaDey69384, @MullickSan22454, @Nishaant_PB, @deepak_iisc and Angana. Wonderful to be collaborating with you on this work and looking at #actin #isoforms in #yeast and #mammalian_cells using #UExM.

On my way to the #NeuroFrance2025 in Montpellier ! Looking forward to see exciting science and present my recent work to the community

Join me May 20 @ 11 AM ET for a webinar with Bio-protocol!

I'll walk through our single-shot 20-fold expansion microscopy (20ExM) method + share the full protocol so you can try it too.

We dedicated this paper to Michel Bornens who passed away 3 years ago. He would have enjoyed this movie so much!

A Morpho-Proteomic Atlas of Mitosis at Sub-Minute Resolution https://www.biorxiv.org/content/10.1101/2025.04.09.647158v1

📣Application deadline for #EMBLFluorescenceLifetime is approaching ⏰

Do you have experience in fluorescence microscopy and want to enhance your skills in confocal fluorescence microscopy and in lifetime-based readouts?

Then apply for this hands-on course by 21 April: ➡️s.embl.org/lef25-01-bl

📣 New issue online! www.embopress.org/toc/17574684...

The cover highlights the study by M. Pavlou, @tomreh.bsky.social et al. @uwmedicine.bsky.social 👉 Vector-mediated expression of proneural genes in retinal #MüllerGlia drives #neurogenesis in adult mammalian retina

Scientific image: M. Pavlou

But… we couldn’t easily find more tubes in tomograms 🤔 We turned to expansion microscopy (ExM)! Thanks to an amazing intro from @centriolelab.bsky.social & @marinelap.bsky.social, we learned how to do ExM 🔬💥. After many gels, we finally observed Atub filaments in a small subpopulation of cells. 4/6

Of wow congrats for this massive piece of work !
Well done on making the expansion of Asgard to work :):):)!

I’m honored to receive this award for my research achievements in cell biology ! Many thanks to the @sbcf.bsky.social !

We are hiring!
As part of the EU-funded Marie Skłodowska-Curie Action training network "Cilia-AI" we have two fully funded PhD positions available in our group in Paris @institutimagine.bsky.social

For more information:
www.cilia-ai.eu
www.institutimagine.org/en/sophie-sa...