That’s how it looks like

15.10.2025 15:18 — 👍 1    🔁 0    💬 0    📌 0

This is how the complex structures look like on 3D youtu.be/lAZrYsnoLBc?...

Credit: @pdracakowski.bsky.social

15.10.2025 14:44 — 👍 0    🔁 0    💬 0    📌 0

What a day! We published two papers describing the lives of proteins from Alpha shorturl.at/ZeAG7 to Omega shorturl.at/b79Eu

Seeing these processes through the lens of structural biology is so satisfying

15.10.2025 13:12 — 👍 2    🔁 1    💬 0    📌 0

Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome Nature Communications - K11/K48 branched ubiquitin chains regulate protein degradation and cell cycle progression. Here, the authors report the structural basis of how such a branched ubiquitin...

Excited to share our Nature Communications paper 🎉 rdcu.be/eK7wG
We uncovered by cryoEM how the human proteasome recognizes branched K11/K48 ubiquitin chains through a new K11-binding site in the RPN2 subunit, revealing how the proteasome precisely identifies targets for rapid turnover. #cryoEM

15.10.2025 10:16 — 👍 5    🔁 5    💬 1    📌 0

Validate User

We discovered how an engineered ribosome arrest peptide (eRAP) acts as a built-in “pause button” to precisely control protein synthesis. eRAP merges two natural stalling systems to stop the ribosome at just the right time — shaping how nascent proteins begin to fold.
academic.oup.com/nar/article/...

15.10.2025 02:28 — 👍 7    🔁 5    💬 1    📌 0