Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field
www.annualreviews.org/content/jour...
These are not a ranking lists we should be topping...
royalsociety.org/-/media/poli...
Wonderful to see the seminal discoveries of Shimon Sakaguchi, Mary E. Brunkow & Fred Ramsdell recognised with the Nobel Prize. From Sakaguchi’s discovery of Treg cells to the identification of Foxp3, their research opened a new chapter in immunology, viewed from the prism of dominant tolerance.
06.10.2025 21:56 — 👍 10 🔁 2 💬 0 📌 0
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
06.10.2025 11:21 — 👍 154 🔁 72 💬 2 📌 12
Nobel prize for Tregs!
www.nobelprize.org/prizes/medic...
Kristoffer H Johansen presenting a talk at the Dept of Pathology, University of Cambridge.
Great to welcome former PhD student, now Assistant Professor @krishaurum.bsky.social of the DTU back to the Department of Pathology. Excellent presentation on TIL TCRs, peptide-MHC complexes and his recent paper on AI-designed pMHC binders (artificial TCRs).
02.10.2025 16:17 — 👍 3 🔁 0 💬 0 📌 1
Listen to James Edgar @campathology.bsky.social discuss cosmetic use of exosomes on BBC Radio 4 Inside Health: www.bbc.co.uk/sounds/play/...
(Spoiler alert: he does not approve).
Amazing new paper from @krishaurum.bsky.social and colleagues, designing novel pMHC-binders (synthetic TCRs) in silico: www.science.org/doi/10.1126/...
28.07.2025 07:39 — 👍 6 🔁 1 💬 0 📌 0
We're recruiting a postdoc to join my lab at @oncology.ox.ac.uk & @oxcio.bsky.social to understand immune regulation in cancer and develop new approaches for cancer prevention and metastasis.
Deadline: 11 August 2025
my.corehr.com/pls/uoxrecru...
Lab info: www.oncology.ox.ac.uk/team/jie-yang
I've been incredibly lucky to be supported by the @erc.europa.eu with a Start, Consolidator and now Advanced grant! Each of these awards enabled 'blue skies' research into the immune system, as well as resulting in direct translational impact on patients and via commercialisation. 🥰
17.06.2025 10:18 — 👍 48 🔁 2 💬 5 📌 0I am delighted to see that Len Stephens, my colleague and PI3K pioneer, has been awarded the 2026 Biochemical Society Morton Lecture for outstanding contributions to lipid biochemistry! www.babraham.ac.uk/news/2025/04...
08.04.2025 08:51 — 👍 19 🔁 3 💬 2 📌 0
New research article from the lab led by the amazing @amydashwood.bsky.social !
In collaboration with @vib-switch-lab.bsky.social @cbdresearch.bsky.social we engineered variants of #IL2 designed for therapeutic use. 1/11
www.sciencedirect.com/science/arti...
Last few days to apply for this:
07.03.2025 13:33 — 👍 1 🔁 3 💬 0 📌 0
Listen to Rahul talk about the study about 20 min into this programme: www.bbc.co.uk/sounds/play/...
05.03.2025 19:12 — 👍 0 🔁 0 💬 0 📌 0
Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U
05.03.2025 18:56 — 👍 105 🔁 46 💬 2 📌 2
Excellent article by James Gallagher at the BBC summarising the study and its implications:
"Scientists crack how aspirin might stop cancers from spreading"
www.bbc.co.uk/news/article...
Brilliant new paper from Jie Yang @jieyang437.bsky.social and Rahul Roychoudhuri @roychoudhurilab.bsky.social linking aspirin to immune-mediated prevention of cancer metastasis.
www.nature.com/articles/s41...
📢 Calling all Signallers! Join us for this celebratory smorgasbord of signalling research on 1-2 May with sessions on #proteostasis, #PI3K, #autophagy, #redox biology and #nuclear signalling. 🧪
Latest Institute research with special guests ⤵️
www.eventbrite.co.uk/e/cellular-s...
Seems dystopian, but this is now reality. Promoting diversity, equality and inclusiveness has become a crime and they are threatened to report anyone engaged in such activities. Free speech no longer applies.
09.02.2025 19:51 — 👍 0 🔁 0 💬 0 📌 0Welcome!
26.01.2025 16:12 — 👍 0 🔁 0 💬 0 📌 0
📢 New position! We are recruiting an Associate Professor / Professor of Infection and/or Immunity to join our innovative research community!
Find out more about the position and apply: https://buff.ly/40m1udb
Many congratulations to Prof Ashley Moffett on this honour!
This is in recognition of her long and impactful research on the genetics and immunology of maternal and foetal health, especially as related to pre-eclampsia and and the role of NK cells in the development and function of the placenta.
A very rare position for an immunology professorship at Cambridge. Something to think about!
www.jobs.cam.ac.uk/job/49381/
I've added a PI3K starter pack.
Please help me populate it by replying to this post.
#PI3K #PTEN #AKT #mTOR #FOXO
go.bsky.app/7p2g5eN
A starter pack for PhD students and Postdocs in Immunology to connect 🔽
Drop a 🧬 and I'll add you to the list.
Let's build the upcoming immuno community!
#ImmunoSky 🧪
go.bsky.app/RABVXY4
Really great talk!
03.12.2024 17:07 — 👍 1 🔁 0 💬 1 📌 0🙋
02.12.2024 20:47 — 👍 0 🔁 0 💬 1 📌 0It's what happens to mice if they don't have Foxp3+ Treg to keep the immune system in check. Unpleasant and lethal.
29.11.2024 17:02 — 👍 0 🔁 0 💬 0 📌 0
Professorship in Immunity and Infection at the University of Cambridge:
www.jobs.cam.ac.uk/job/49381/
Check out the cross-departmental infection and immunity theme for the grand challenges we want to address:
www.bio.cam.ac.uk/research/inf...
Application deadline: Jan 26th, 2025.
