Ella Hartenian

Merci ☺️

Trois récipiendaires Ambizione rejoignent la FBM Cette année, trois jeunes scientifiques viennent renforcer la Faculté de biologie et de médecine (FBM) de l’Unil. Lauréat·es des subsides Ambizione du Fonds national suisse, Ella Hartenian, David Robe...

👏 Félicitations aux lauréat·es du programme #Ambizione 2024 @snsf.ch 👉 Ella Hartenian, David Robertson et Sivaniya Subramaniapillai, qui lancent leurs propres groupes de #recherche au sein de la faculté.
🔗 www.unil.ch/news/fr/1764...

@ehartenian.bsky.social @sivaniya.bsky.social @unil.bsky.social

Thank you @dib-unil.bsky.social. I’m very excited to be starting the next chapter of my career at the DIB!

Trois récipiendaires Ambizione rejoignent la FBM Cette année, trois jeunes scientifiques viennent renforcer la Faculté de biologie et de médecine (FBM) de l’Unil. Lauréat·es des subsides Ambizione du Fonds national suisse, Ella Hartenian, David Robe...

Congratulations and welcome to Ella Hartenian @ehartenian.bsky.social, who will be launching her group in our Department of Immunobiology in 2026!

www.unil.ch/news/fr/1764...

Thanks to Magalie for her experimental support, Petr for his guidance and the lab for the lively discussions. @dib-unil.bsky.social @emboreports.org

Annndddd it’s out! Here’s what came out of combining my virology background with the @brozlab.bsky.social’s cell death focus : a novel role for the cell death protein ninj1 during hsv1 infection. In brief, Ninj1 on mouse macrophages results in lower infection rates and higher cytokine secretion.

NINJ1 blocks HSV-1 entry into macrophages to impact viral replication and immunity | EMBO reports imageimageNINJ1 blocks HSV-1 entry into mouse macrophages independent of its role in cell death, resulting in greater secretion of pro inflammatory cytokines downstream of infection. Mouse macrophages lacking NINJ1 are more permissive to HSV-1 ...

November is a big month for the lab with *two* new papers by @ehartenian.bsky.social and @alexandraboegli.bsky.social ++ co authors now online.

www.embopress.org/doi/full/10....

It’s DIB day! The annual conference for our department @dib-unil.bsky.social. Lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @elliottbernard.bsky.social 🔬!

Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne!

@brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social

No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org

📣Save the date! 📣
We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year.
We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!

Sign The Open Letter to Stand Up For Science Now! Science is under siege. Trump’s latest Executive Order calls for politically appointed science commissars to evaluate research. Join us in adding your name to our open letter condemning Trump’s escala...

🚨 URGENT RESPONSE CALL 🚨

Trump’s Fool’s Gold Science EO is a dangerous sham.
It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda.

We’ve launched an open letter.

SIGN & SHARE NOW: actionnetwork.org/petitions/op...

eft: A 2D CryoSXT projection of an HSV-1 evelopment event. Right: A 3D rendering of the budding assembly stage captured by CLXT.

A new combination of microscopy methods has revealed exquisite details of the virus assembly process used by herpes simplex virus during replication.
buff.ly/aO8W9BJ

Our research shows that ~50% of mothers globally decline at least half of opportunities to participate in conferences after becoming parents (N=3995). We understand the barriers and are offering Travel Grants to help overcome these challenges.
Apply now - deadline 31st March!
shorturl.at/gnCU2

Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!

I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...

List of Stand Up for Science events—official events in red, solidarity events in blue.

SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!

To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎

Get in Dorks, we are going protesting.

STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS.

More information to come.

Sign the Petition Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

NYGC is organizing a number of efforts to address the changes to NIH IDCs and other changes to federal policy. If you are a US citizen, or in the US working in science, please consider signing this petition. The more signatures the stronger our hand in interacting with law makers. chng.it/kK2HMP5pGk

Making Sense of It All Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...

Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences.

Every Friday, I debrief you over a drink at
buttondown.com/liminalcreat...

The excellent Swiss Virology Meeting just ended. Thanks to the organizers and participants for making it such a warm and collegial environment. Here Magalie and I are with the project that began as her masters project. 🦠🚀

Happy to share the first preprint from my lab by
@indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity!

Check out Indra’s thread for a summary:

We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland.

Registrations open March 1 - Attendance limited to 150 participants.

More info: wp.unil.ch/immunobiolog...

#ImmunoSky

Sterile- or pathogen-induced endolysosomal damage activate the NLRP6 inflammasome in human intestinal epithelial cells NLRP6 controls host defense against bacteria and viruses in the gastrointestinal tract by a poorly understood mechanism. Here, we report that NLRP6 forms an inflammasome upon endolysosomal damage caus...

Check out our latest pre print! Alexandra and colleagues show that the enigmatic inflammasome receptor, NLRP6 is activated by sterile and pathogen induced endolysosomal damage. Hot off the press!

www.biorxiv.org/content/10.1...

For those who haven't been following the cozying up to RFK Jr. by some liberals (call them what you want, they are not Republicans) and why it's dangerous. Three pieces to lay out the case. 1/

The class gap in career progression: US academia

First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree.

mitsloan.mit.edu/shared/ods/d...

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures Researchers in the MIT Jameel Clinic for Machine Learning in Health developed a fully open-source biomolecular structure prediction model that achieves state-of-the-art performance, at the level of Al...

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures

With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly

www.eurekalert.org/news-release...

Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 year...

A new genomic study in Science encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neanderthal gene flow into early modern humans left an indelible mark on human evolution. scim.ag/4gkMvpz

It's that time of year. Confocal + Christmas = Xmas Tree, Ymas Tree, and our favorite Zmas tree. #microscopy #confocal #imaging

Interested in learning more about NINJ1? My colleagues in the @brozlab.bsky.social, including @ehartenian.bsky.social, wrote a nice review of our current knowledge. www.cell.com/trends/bioch...