Harry Low’s Lab 's Avatar

Harry Low’s Lab

@lowlab.bsky.social

Bacterial pathogenesis. Antibiotic discovery. Membrane remodelling. Structural biology #cryoEM @Imperial College, London thelowlab.org

3,017 Followers  |  727 Following  |  62 Posts  |  Joined: 08.10.2023  |  2.1131

Latest posts by lowlab.bsky.social on Bluesky

#ArchaeaSky

10.10.2025 10:27 — 👍 9    🔁 5    💬 0    📌 1
Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)

Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...

09.10.2025 12:17 — 👍 24    🔁 35    💬 0    📌 1

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

03.10.2025 16:06 — 👍 46    🔁 84    💬 0    📌 2

Now published! www.nature.com/articles/s41...

Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.

29.09.2025 14:24 — 👍 43    🔁 24    💬 1    📌 0

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

27.09.2025 11:06 — 👍 55    🔁 51    💬 0    📌 1

Do you #PhD with us!

23.09.2025 08:13 — 👍 7    🔁 1    💬 0    📌 0
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Computing the Human Interactome Protein-protein interactions (PPI) are essential for biological function. Recent advances in coevolutionary analysis and Deep Learning (DL) based protein structure prediction have enabled comprehensiv...

😵

Computing the Human Interactome (200 million predicted protein structures) by the Baker lab #alphafold 🧶🧬

www.biorxiv.org/content/10.1...

the db : prodata.swmed.edu/humanPPI/

02.10.2024 10:31 — 👍 12    🔁 8    💬 2    📌 1

Stunning!

25.09.2025 19:27 — 👍 1    🔁 0    💬 1    📌 0

No it’s great.. sorry if I wasn’t clear! Love that we’re getting even close. Wonderful paper!

14.09.2025 13:40 — 👍 1    🔁 0    💬 0    📌 0

‘We expect that this approach may be useful for cryo-EM analysis of other small particles near or below the theoretical size limit.’ 🤯

13.09.2025 18:17 — 👍 8    🔁 0    💬 1    📌 1
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Assistant Professor (Research and Education) in Bacterial Genomics at University of Birmingham Looking for a new job opportunity in academia? Check out this job opening for a Assistant Professor (Research and Education) in Bacterial Genomics on jobs.ac.uk!

Reminder that we are recruiting an Assistant Professor Bacterial Genomics @imibirmingham.bsky.social.

www.jobs.ac.uk/job/DOO184/a...

Deadline 24 Sept.

06.09.2025 20:08 — 👍 18    🔁 28    💬 0    📌 0

Cool new pilus architecture..

02.09.2025 22:01 — 👍 0    🔁 0    💬 0    📌 0
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We are recruiting 2 postdocs to work on bacterial motility using a combination of cryoEM, FLM and MD. An exciting collaboration with Kirsty Wan @micromotility.bsky.social Wolfram Moebius @wolframmoebius.bsky.social and Daniel Kattnig. Please see links in the thread below!

28.08.2025 09:13 — 👍 27    🔁 15    💬 2    📌 2
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Postdoctoral Research Associate in Molecular Microbiology

🚨 Job alert 🚨

I’m recruiting two postdoctoral research associates to join my lab at KCL to study how #Klebsiella pneumoniae regulates virulence factor expression during infection! #klebclub

Mol Micro: tinyurl.com/mtrwtx5e

Infection: tinyurl.com/2s3u8ca2

Deadline: 21st September.

26.08.2025 14:40 — 👍 23    🔁 30    💬 1    📌 3
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New endowed professorship strengthens climate research at the University of Basel The University of Basel is setting up a new endowed professorship at the Biozentrum to make fundamental discoveries at the interface between biophysics and climate-relevant environmental biology. This...

🧪 The University of Basel is setting up a new endowed professorship in #ClimateBiophysics at the @biozentrum.unibas.ch, funded by the Georg H. Endress Foundation. This new professorship strengthens climate research @unibas.ch. www.biozentrum.unibas.ch/news/detail/...

26.08.2025 07:09 — 👍 58    🔁 39    💬 1    📌 2
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Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation Antibiotic resistance is among the greatest threats of the modern era. Multidrug efflux pumps expel antibiotics from bacterial cells and present a particular challenge by conferring resistance to a br...

New preprint from the lab, in collaboration with Ed Tate, Nate Traaseth and many others!

www.biorxiv.org/content/10.1...

23.08.2025 11:24 — 👍 25    🔁 9    💬 1    📌 0
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We're looking for an awesome computational #postdoc to join our group @PioneerCampus. You'll explore native cells with #cryoET, get long-term funding (5+ years), and live in Munich! For more info, see our new Cell Architecture Lab website:...

13.08.2019 16:07 — 👍 11    🔁 10    💬 2    📌 1

Check this out 👇

20.08.2025 17:14 — 👍 3    🔁 0    💬 0    📌 0
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Our collaborative work on the T9SS is just out in Nature Communications! Fantastic work led by Dhana Gorasia and Eric Hanssen. This paper reveals the structure of the T9SS outer membrane PorKN ring complex and mechanistic insights into protein secretion. www.nature.com/articles/s41...

20.08.2025 13:21 — 👍 20    🔁 3    💬 1    📌 0

Extremely excited for the second version of this workshop at the MPI of Biophysics l, Frankfurt, that will happen 12-20. April 2026. Absolutely amazing lineup of speakers, I am very much looking forward to learning from everyone! Apply here: meetings.embo.org/event/26-in-...

15.08.2025 16:09 — 👍 40    🔁 18    💬 0    📌 0
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WORK!

I currently have 5 (!) open positions for postdocs/PhD students in our CDlab for projects:

- Nanopore protein sequencing
- Archaeal CDV cell division
- Microfluidics for synthetic cells
- Nuclear Pore Complex
- Origami mimics of peroxisomes

Please apply! ceesdekkerlab.nl/come-join-us/

RT=👍

13.08.2025 13:30 — 👍 23    🔁 30    💬 2    📌 5
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Please RT 🙏 If you’re an early career researcher working in the fields of structural or synthetic biology wishing to start your lab then come join us at Imperial. We’re looking to support outstanding individuals for external Career Development Awards/Fellowships.

www.imperial.ac.uk/media/imperi...

11.08.2025 16:05 — 👍 14    🔁 21    💬 1    📌 0
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VACANCY - We’re recruiting for a visionary group leader to lead fundamental research on Discovery Plant Science as part of our vibrant research community

Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:

www.jic.ac.uk/vacancies/gr...

09.08.2025 17:15 — 👍 31    🔁 42    💬 0    📌 2
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Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...

08.08.2025 07:52 — 👍 68    🔁 65    💬 1    📌 4

That’s cool. By growing in liquid culture in lower oxygen levels treating like a microaerophile can antibiotic be induced? Or too simplistic?

07.08.2025 17:42 — 👍 0    🔁 0    💬 1    📌 0

Ever wondered why some antibiotics are made by Streptomyces on agar plates but not in liquid cultures? Read this work on redox control of antibiotic biosynthesis. Led by katienoble241.bsky.social and Rebecca Devine, and in collaboration with @barriewilks.bsky.social

journals.asm.org/doi/10.1128/...

07.08.2025 16:30 — 👍 73    🔁 35    💬 6    📌 1
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We have a postdoc opening for a protistologist with biophysics inclinations to join our @hfspo.bsky.social project! (focus will be on characterising the morphology, ultrastructure and behaviour of excavates) #protistsonsky

Apply by Sept 17th (RTs appreciated!)
jobs.exeter.ac.uk/hrpr_webrecr...

06.08.2025 19:19 — 👍 47    🔁 49    💬 1    📌 0
The Budke Lab in the Department of Ecology & Evolutionary Biology at the University of Tennessee (http://jmbudke.github.io/) is seeking a Post-Doctoral Research Associate to work on an NSF-funded project. This project is investigating morphological evolution in a phylogenetic context using moss plants as the experimental system. 
The research responsibilities will include (1) assembling morphological datasets using the literature and herbarium specimens, (2) compiling DNA sequence datasets from publicly available resources and laboratory-based methods using herbarium specimens, and (3) combining these data to analyze the evolution of morphological structures across a phylogeny. 
Opportunities will also be available to develop novel research questions focusing on the functional morphology, physiology, and evolution of the parent-offspring relationship in mosses. Supervising and mentoring undergraduate researchers in both the laboratory and herbarium will be required. 
An additional aim of this project is to build awareness of and appreciation for plants and botanical natural history collections. As part of the team, the postdoc will participate in hands-on outreach events, such as Darwin Day. The postdoc will also co-lead a May-term course for undergraduate students on collections-based research.
Apply by 17 August 2025 for full consideration.

The Budke Lab in the Department of Ecology & Evolutionary Biology at the University of Tennessee (http://jmbudke.github.io/) is seeking a Post-Doctoral Research Associate to work on an NSF-funded project. This project is investigating morphological evolution in a phylogenetic context using moss plants as the experimental system. The research responsibilities will include (1) assembling morphological datasets using the literature and herbarium specimens, (2) compiling DNA sequence datasets from publicly available resources and laboratory-based methods using herbarium specimens, and (3) combining these data to analyze the evolution of morphological structures across a phylogeny. Opportunities will also be available to develop novel research questions focusing on the functional morphology, physiology, and evolution of the parent-offspring relationship in mosses. Supervising and mentoring undergraduate researchers in both the laboratory and herbarium will be required. An additional aim of this project is to build awareness of and appreciation for plants and botanical natural history collections. As part of the team, the postdoc will participate in hands-on outreach events, such as Darwin Day. The postdoc will also co-lead a May-term course for undergraduate students on collections-based research. Apply by 17 August 2025 for full consideration.

Looking for a #postdoc position in evolutionary biology?
Come join the Budke Lab @utknoxville.bsky.social! Read more about the lab jmbudke.github.io & apply here fa-ewlq-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...
Please share widely. Thanks!
#Postdocposition #PostdocOpportunity

22.07.2025 11:01 — 👍 41    🔁 50    💬 1    📌 0
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Escherichia coli with a 57-codon genetic code The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here we designed and generated Escherichia coli with a 4 Mb synthetic genome in which we re...

Escherichia coli with a 57-codon genetic code | Science. Syn57, uses 55 codons to encode the 20 canonical amino acids. #rnasky #microsky 🦠 www.science.org/doi/10.1126/...

01.08.2025 15:36 — 👍 7    🔁 6    💬 0    📌 0

🤩👇🏻❗️

01.08.2025 16:47 — 👍 2    🔁 1    💬 0    📌 0

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