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Harry Low’s Lab

@lowlab.bsky.social

Bacterial pathogenesis. Antibiotic discovery. Membrane remodelling. Structural biology #cryoEM @Imperial College, London thelowlab.org

2,975 Followers  |  730 Following  |  56 Posts  |  Joined: 08.10.2023  |  2.0406

Latest posts by lowlab.bsky.social on Bluesky

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VACANCY - We’re recruiting for a visionary group leader to lead fundamental research on Discovery Plant Science as part of our vibrant research community

Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:

www.jic.ac.uk/vacancies/gr...

09.08.2025 17:15 — 👍 16    🔁 29    💬 0    📌 1
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Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...

08.08.2025 07:52 — 👍 59    🔁 58    💬 1    📌 4

That’s cool. By growing in liquid culture in lower oxygen levels treating like a microaerophile can antibiotic be induced? Or too simplistic?

07.08.2025 17:42 — 👍 0    🔁 0    💬 1    📌 0

Ever wondered why some antibiotics are made by Streptomyces on agar plates but not in liquid cultures? Read this work on redox control of antibiotic biosynthesis. Led by katienoble241.bsky.social and Rebecca Devine, and in collaboration with @barriewilks.bsky.social

journals.asm.org/doi/10.1128/...

07.08.2025 16:30 — 👍 74    🔁 34    💬 6    📌 1
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We have a postdoc opening for a protistologist with biophysics inclinations to join our @hfspo.bsky.social project! (focus will be on characterising the morphology, ultrastructure and behaviour of excavates) #protistsonsky

Apply by Sept 17th (RTs appreciated!)
jobs.exeter.ac.uk/hrpr_webrecr...

06.08.2025 19:19 — 👍 37    🔁 43    💬 0    📌 0
The Budke Lab in the Department of Ecology & Evolutionary Biology at the University of Tennessee (http://jmbudke.github.io/) is seeking a Post-Doctoral Research Associate to work on an NSF-funded project. This project is investigating morphological evolution in a phylogenetic context using moss plants as the experimental system. 
The research responsibilities will include (1) assembling morphological datasets using the literature and herbarium specimens, (2) compiling DNA sequence datasets from publicly available resources and laboratory-based methods using herbarium specimens, and (3) combining these data to analyze the evolution of morphological structures across a phylogeny. 
Opportunities will also be available to develop novel research questions focusing on the functional morphology, physiology, and evolution of the parent-offspring relationship in mosses. Supervising and mentoring undergraduate researchers in both the laboratory and herbarium will be required. 
An additional aim of this project is to build awareness of and appreciation for plants and botanical natural history collections. As part of the team, the postdoc will participate in hands-on outreach events, such as Darwin Day. The postdoc will also co-lead a May-term course for undergraduate students on collections-based research.
Apply by 17 August 2025 for full consideration.

The Budke Lab in the Department of Ecology & Evolutionary Biology at the University of Tennessee (http://jmbudke.github.io/) is seeking a Post-Doctoral Research Associate to work on an NSF-funded project. This project is investigating morphological evolution in a phylogenetic context using moss plants as the experimental system. The research responsibilities will include (1) assembling morphological datasets using the literature and herbarium specimens, (2) compiling DNA sequence datasets from publicly available resources and laboratory-based methods using herbarium specimens, and (3) combining these data to analyze the evolution of morphological structures across a phylogeny. Opportunities will also be available to develop novel research questions focusing on the functional morphology, physiology, and evolution of the parent-offspring relationship in mosses. Supervising and mentoring undergraduate researchers in both the laboratory and herbarium will be required. An additional aim of this project is to build awareness of and appreciation for plants and botanical natural history collections. As part of the team, the postdoc will participate in hands-on outreach events, such as Darwin Day. The postdoc will also co-lead a May-term course for undergraduate students on collections-based research. Apply by 17 August 2025 for full consideration.

Looking for a #postdoc position in evolutionary biology?
Come join the Budke Lab @utknoxville.bsky.social! Read more about the lab jmbudke.github.io & apply here fa-ewlq-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...
Please share widely. Thanks!
#Postdocposition #PostdocOpportunity

22.07.2025 11:01 — 👍 43    🔁 51    💬 1    📌 0
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Escherichia coli with a 57-codon genetic code The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here we designed and generated Escherichia coli with a 4 Mb synthetic genome in which we re...

Escherichia coli with a 57-codon genetic code | Science. Syn57, uses 55 codons to encode the 20 canonical amino acids. #rnasky #microsky 🦠 www.science.org/doi/10.1126/...

01.08.2025 15:36 — 👍 8    🔁 6    💬 0    📌 0

🤩👇🏻❗️

01.08.2025 16:47 — 👍 2    🔁 1    💬 0    📌 0
Home | Research Group Schmid | University of Basel

💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭:
#nanopores #smFRET #biomolecular #dynamics #singleMolecules

We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.

Please share broadly, thank you!🤝

schmid.chemie.unibas.ch

31.07.2025 14:34 — 👍 31    🔁 29    💬 1    📌 1
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Sub-3 Å resolution protein structure determination by single-particle cryo-EM at 100 keV Cryoelectron microscopy (cryo-EM) has transformed structural biology by providing high-resolution insights into biological macromolecules. We report s…

Now out in Structure: Paper on high-resolution #cryoEM using the 100 kV Tundra cryo-TEM by Dimple Karia, Adrian Koh, @abhaykot.bsky.social, @lingboyu.bsky.social, @landerlab.bsky.social and many others. Happy to have contributed to this effort. Check it out:
www.sciencedirect.com/science/arti...

30.07.2025 21:50 — 👍 77    🔁 37    💬 1    📌 0
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These are from the Cambrian, ~500MYa, with sub-micron details of soft tissue preserved.. remarkable 🤯

www.science.org/doi/10.1126/...

29.07.2025 02:13 — 👍 9    🔁 1    💬 0    📌 0
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We are hiring! "Researcher in DNA-Based Information Processing Systems" (PhD or postdoc level). Co-supervision by Prof. Ralf Reussner (KIT computer science) and myself (biological systems). Combination of experiments and computational work. Please Apply / Repost!

www.pse.kit.edu/english/karr...

29.07.2025 06:24 — 👍 9    🔁 12    💬 1    📌 0

Thanks Kate!

29.07.2025 22:27 — 👍 1    🔁 0    💬 0    📌 0
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Delighted to share the final version of Richard Zhou's study on how the CD163 scavenger receptor cleans up after toxic haemoglobin spills out from our blood cells. An amazing grabber mechanism!
rdcu.be/ewPA2

18.07.2025 13:39 — 👍 22    🔁 10    💬 0    📌 0

Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏

www.imperial.ac.uk/media/imperi...

28.07.2025 16:13 — 👍 19    🔁 30    💬 0    📌 1

Love this paper.. 👏

27.07.2025 19:39 — 👍 2    🔁 0    💬 1    📌 0
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The Last of Us: Developing a Genomic Epidemiology Toolkit for Fungal Outbreaks at University of Birmingham on FindAPhD.com PhD Project - The Last of Us: Developing a Genomic Epidemiology Toolkit for Fungal Outbreaks at University of Birmingham, listed on FindAPhD.com

Last week to apply for TWO PhDs with me and amazing supervisors at University of Birmingham

The Last Of Us - www.findaphd.com/phds/project...

Understanding pathogen diversity in maternal and neonatal populations - www.findaphd.com/phds/project...

I’m on holiday so can’t answer queries though

24.07.2025 16:55 — 👍 12    🔁 12    💬 0    📌 0
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1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler

Tons of open slots, invited and selected speakers all get 20 mins ❤️

#EESNucleus

23.07.2025 10:49 — 👍 58    🔁 34    💬 1    📌 2

More incredible glimpses of Asgard archaea architecture and lifestyle.. 👏

23.07.2025 21:52 — 👍 7    🔁 1    💬 0    📌 0
Research Associate - Microbial Metabolomic Research Associate - Microbial Metabolomic

*JOB AD*: interested in doing a postdoc in microbial metabolomics? Passionate about natural products mass spec?

Come join the group! Informal enquires welcome!

Closing Date: 19 August 2025

jobs.ncl.ac.uk/job/Newcastl...

22.07.2025 14:32 — 👍 21    🔁 31    💬 0    📌 3
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💥 Excited to introduce Bacformer 🦠 - the first foundation model for bacterial genomics. Bacformer represents genomes as sequences of ordered proteins, learning the “grammar” of how genes are arranged, interact and evolve.

Preprint 📝: biorxiv.org/content/10.1...

🧵 1/n

21.07.2025 09:55 — 👍 91    🔁 58    💬 3    📌 2
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Twitching motility suppressors reveal a role for FimX in type IV pilus extension dynamics In Pseudomonas aeruginosa, retractable protein filaments called type IV pili (T4P) facilitate surface adherence, sensing, and directional movement known as twitching motility. T4P are necessary for th...

New paper alert! PhD candidate Nathan Roberge is studying regulation of the #T4P assembly ATPase PilB and identified suppressors of FimX with enhanced motility. Where did they map? Find out here: www.biorxiv.org/content/10.1...

15.07.2025 17:12 — 👍 8    🔁 3    💬 1    📌 0
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Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).

14.07.2025 12:09 — 👍 25    🔁 33    💬 0    📌 4
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❗️ Exciting review alert❗️focussing on the evolution and mechanism of prokaryotic ESCRT-III-like systems.. fun collaboration with Tom Williams @tweethinking.bsky.social!

doi.org/10.1016/j.sb...

14.07.2025 17:19 — 👍 11    🔁 1    💬 0    📌 0
Portail Emploi CNRS - Offre d'emploi - Ingénieur d'Etude en Microbiologie (H/F)

We have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested:

emploi.cnrs.fr/Offres/CDD/U...

08.07.2025 14:54 — 👍 23    🔁 32    💬 0    📌 0
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We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...

30.06.2025 14:34 — 👍 19    🔁 34    💬 1    📌 0

Congratulations to the Liu Lab 👏

30.06.2025 20:17 — 👍 0    🔁 0    💬 0    📌 0
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In-situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper for effector translocation The Dot/Icm machine in Legionella pneumophila is one of the most versatile type IV secretion systems (T4SSs), with a remarkable capacity to translocate over 330 different effector proteins across the ...

In-situ SPA 🧨

www.biorxiv.org/content/10.1...

30.06.2025 20:16 — 👍 11    🔁 7    💬 1    📌 0
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Postdoctoral Scientist - Structural Studies - Dr Sjors Scheres - LMB 2640 - Cambridgeshire job with MRC Laboratory of Molecular Biology (LMB) | 12840844 Postdoctoral Scientist Starting Salary: £41,344 Fixed term: 3 years MRC Laboratory of Molecular Biology, Cambridge, UK We are looking for a postdoc...

We have a 3-year funded postdoc position to work on structures of #amyloid filaments. If you are an expert in protein biochemistry, structural biology or #cryoEM / #cryoET, this could be for you! Feel free to email me with any questions. Come join us! 🤩

www.nature.com/naturecareer...

25.06.2025 14:01 — 👍 55    🔁 42    💬 0    📌 1

Postdoc positions open in my lab (Francis Crick Institute) to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

20.06.2025 09:38 — 👍 77    🔁 80    💬 1    📌 2

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