@jongminkmg.bsky.social
Assistant Professor @Cornell University - Germline gene regulation, gene silencing, chromatin - jongminkimlab.org
Exciting work on orphan genes in fertilization and evolution!
18.09.2025 02:40 — 👍 3 🔁 0 💬 0 📌 0Congrats, Anna! 🎉
14.09.2025 00:32 — 👍 0 🔁 0 💬 0 📌 0
Avidity.
In plants, PRC2 accessory VEL proteins polymerize much like PRC1 subunits in animals, reinforcing silencing. Multimerization - overcoming weak affinity through 'avidity' - seems to be an important conserved principle in chromatin regulation.
pubmed.ncbi.nlm.nih.gov/40858112/
Donated. FlyBase is a truly essential resource!
25.08.2025 03:11 — 👍 7 🔁 0 💬 0 📌 0Congrats, Ellen! This is so exciting 😊
22.08.2025 03:01 — 👍 1 🔁 0 💬 1 📌 0Thanks for the explanation, Li. It is a good reminder to me not to assume all Aly-class genes regulate the same targets. Looking forward to learn what you find about their roles in de novo genes. Congrats again!
16.07.2025 23:48 — 👍 1 🔁 0 💬 0 📌 0Exciting work!
Many Achi/Vis targets seem not expressed in the tMAC (aly) mutant (as you discussed). Curious if Aly motif (AGYWGGC) sits upstream of Achi/Vis motif in de novo genes. If so, it is interesting how selection resulted in a simple, but still reasonably complex regulatory syntax.
A brief mountain break.
15.07.2025 01:23 — 👍 6 🔁 0 💬 0 📌 0Reducing H1 levels (by CRAMP1 KD) derepresses PRC2 target genes without reducing H3K27me3. It was interesting:
1) once again, H3K27me3 mark alone seems not sufficient for gene repression,
2) how is H1 deposited at Polycomb target sites?
Congrats, Iva!
Beautifully written, Susanna! 😊
13.06.2025 22:32 — 👍 1 🔁 0 💬 0 📌 0True: my ESI MIRA, submitted last February, was withdrawn three weeks before the study section because of a support letter. No sub-award, no expected co-authorship, just a letter. So be careful - their definition of 'collaboration' is very broad.
13.06.2025 22:25 — 👍 2 🔁 0 💬 2 📌 0Congrats, Susanna!! 🎉
11.06.2025 02:29 — 👍 1 🔁 0 💬 0 📌 0Congrats on your exciting work!
08.06.2025 13:33 — 👍 1 🔁 0 💬 0 📌 0I find unstructured regions in proteins enigmatic and very interesting.
06.06.2025 20:51 — 👍 5 🔁 1 💬 1 📌 0Congrats on your exciting work!
06.06.2025 20:45 — 👍 2 🔁 0 💬 1 📌 0Great news! Congratulations!! 🎉
17.05.2025 03:06 — 👍 1 🔁 0 💬 0 📌 0" The common genetic marker Stubble influences Fab2L transgene expression" - balancer and marker mutations are not always inert.
13.03.2025 03:48 — 👍 0 🔁 0 💬 0 📌 0Thank you. I emailed his office.
11.02.2025 13:04 — 👍 1 🔁 0 💬 0 📌 0
Today’s the day! I’m happy to announce that the Murphy Lab will be moving to Cornell this July! The lab will be in Biotech and I’ll be joining the Department of Molecular Biology and Genetics. There will be lots of recruiting soon, including students and postdocs. Please RT. 🙏 TY.
28.01.2025 19:40 — 👍 14 🔁 5 💬 4 📌 2Great opportunity for postbacs to do exciting research and gain experience before graduate school!
22.01.2025 03:15 — 👍 0 🔁 0 💬 0 📌 0
The sun has been rather scarce in Ithaca lately. Nice to see some sunrise this morning.
21.01.2025 02:41 — 👍 7 🔁 0 💬 0 📌 0Irvine is an exciting place to study TFs, enhancers, and gene regulation!
21.01.2025 02:37 — 👍 1 🔁 0 💬 0 📌 0
Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org
20.01.2025 23:08 — 👍 115 🔁 52 💬 4 📌 1Indeed. I love the inducible chromatin contact experiment.
14.12.2024 18:20 — 👍 2 🔁 0 💬 0 📌 0
