Dr. Jan Zimmermann's Avatar

Dr. Jan Zimmermann

@janzimmermann.bsky.social

Associate Professor of Neuroscience at UMN. Circuit enthusiast, organic or silicon(e). Opinions all mine.

3,059 Followers  |  707 Following  |  500 Posts  |  Joined: 03.07.2023  |  3.3197

Latest posts by janzimmermann.bsky.social on Bluesky

Primates are absolutely critical for developing safe and effective gene therapies

26.11.2025 19:22 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Ventral tegmental area GABA neurons integrate positive and negative valence - Nature Communications The role of ventral tegmental area GABA neurons in behavior is unclear. Here, authors show that VTA GABA but not dopamine neurons integrate positive and negative valence to encode motivational conflic...

So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking

24.11.2025 16:18 β€” πŸ‘ 112    πŸ” 25    πŸ’¬ 6    πŸ“Œ 1

I would be shocked if they did not.

25.11.2025 01:51 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Life of an NHP scientist. Every day… 365 days a year. At the end of any rotation this chart is burned into your retina

24.11.2025 03:52 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank me later!!

22.11.2025 04:53 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Naw man. Cloned pagers and pay phones for barkstale 1. Evan and Stringer still standing though until taken down by burner network. Barkstale. Marlo has the photo clock trick.

22.11.2025 04:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Naw man. Burners not pay phones ;)

22.11.2025 04:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Superior Colliculus Projections Drive Dopamine Neuron Activity and Movement But Not Value To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in...

So stoked to have our image on the cover of this week's issue of Journal of Neuroscience!! @sfnjournals.bsky.social #JNeurosci #SfN25. Check out the final version of the paper here www.jneurosci.org/content/45/4...

19.11.2025 18:15 β€” πŸ‘ 100    πŸ” 15    πŸ’¬ 3    πŸ“Œ 0

Apropos of... well...

I'm reviewing applications for a variety of things right now and can tell when letters are written by AI. There aren't many of them but they do exist. They are... not good.

If you're an academic trainee, choose your mentors wisely.

17.11.2025 19:04 β€” πŸ‘ 10    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1
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How our foray into acute neural recordings from the frontopolar cortex started. Check out Kati Rothenhoefer’s LBP028 poster this afternoon (11/16) to learn about how it’s going. #sfn25 #sfn2025

16.11.2025 14:24 β€” πŸ‘ 24    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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Folks @ #SfN2025 - wondering what to do on this rainy Saturday evening? I've got the solution for you. Come to hear discussions about how we can help advocate for our science and ourselves, meet new & old friends, & enjoy some snacks at the WINE social. 7pm at Deck 655 tonight.

15.11.2025 22:35 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

After the Human Single-Neuron meeting which was really fun, it's time for SfN!
And this year, I *am* looking for a post-doc 😯

16.11.2025 00:03 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

China only stopped exports long after Brain initiative got off the ground.

13.11.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here:
www.ucl.ac.uk/cortexlab/po...

12.11.2025 15:41 β€” πŸ‘ 40    πŸ” 27    πŸ’¬ 0    πŸ“Œ 0

I agree with a lot of what you said but this statement goes too far. Most Chinese NHP labs I have seen are far beyond anything we provide in the US in terms of standards and practices. Same goes for sharing. Many of us are not worried about the things you mentioned but rather β€œleave us a slice”

13.11.2025 00:37 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Congratulations

12.11.2025 01:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I entirely agree.

Research in rodents has enabled remarkable technical advances and deepened our understanding of brainstem circuits and general brain physiology.

However, only NHPs possess cognitive, visual, and motor faculties necessary to advance human-relevant systems neuroscience.

11.11.2025 13:53 β€” πŸ‘ 31    πŸ” 6    πŸ’¬ 4    πŸ“Œ 0

this is a wonderful overview and very exciting. Great work

11.11.2025 21:08 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I did not and yet… it’s a bad year

11.11.2025 19:20 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

agree with you on all counts and we have written about it many times over but you know what gets me the most: Our non NHP colleagues do not seem to see it’s coming for them next nor that if that other country is winning on NHP their work will become not needed either. Oh well.

10.11.2025 20:15 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Can you tell me more Dave.

10.11.2025 18:44 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

this this and this

10.11.2025 17:03 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Good bread is life ! ❀️

09.11.2025 17:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

So inspiring

08.11.2025 04:35 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Fear, monkeys, and institutionalΒ courage When news broke of an explosion inside Harvard’s neurobiologyΒ buildingΒ early Saturday morning, every scientist who works with monkeys felt itβ€”an involuntary jolt, a spike of cortisol, the silent thought:Β what if it had been us? Neither animals nor people were hurt, thankfully. ItΒ doesn’tΒ appear to have been an attack. But it didn’t matter. For those of us who work with monkeys, the fear is always near the surface.

Fear, monkeys, and institutionalΒ courage

When news broke of an explosion inside Harvard’s neurobiologyΒ buildingΒ early Saturday morning, every scientist who works with monkeys felt itβ€”an involuntary jolt, a spike of cortisol, the silent thought:Β what if it had been us? Neither animals nor people…

06.11.2025 19:21 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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πŸ—žοΈTIP: ProLOEWEπŸ‘±πŸΌπŸ§‘πŸΌβ€πŸ¦° with Kristian Kersting+Constantin @c-rothkopf.bsky.social, who bring together modern #AI + #cognitivescience➑️@tuda.bsky.social within LOEWE-WhiteBox. Who, together with their team, have succeeded in obtaining 2 clusters of #excellence with #RAI + #TAM ➑️ proloewe.de/en/proloewe-...

04.11.2025 14:13 β€” πŸ‘ 18    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1

The amount of academics who think this is normal is astonishing to me on a daily basis.

05.11.2025 02:33 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

In Econ it is the ease of writing well formatted equations. Especially before many word processors had even rudimentary ability. Same for Beamer type presentations ;) copy your full on table results easy!!

04.11.2025 02:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

If fucking only !!!

03.11.2025 14:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Oh I bet they are a real thing. So is cognitive dissonance haha

31.10.2025 20:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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