Ellen Foxman

Nasal biomarker testing to rule out viral respiratory infection and triage samples: a test performance study These results demonstrate the utility of a nasopharyngeal biomarker to rule out respiratory infection, with potential applications in outbreak management and/or routine screening in high-risk settings...

#COVID19 revealed the urgent need for better ways to screen for & rule out respiratory virus infection. We present a nasal biomarker screening strategy to prevent & manage outbreaks @eBiomedicine.bsky.social #IDSky #MedSky #lungs @yaleschoolofmed.bsky.social www.thelancet.com/journals/ebi...

ASSIGNMENT: COMMENT ON SCHEDULE F

1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees.

www.regulations.gov/commenton/OP...

1/n

The scientists aiming to stay ahead of bird flu on dairy farms and prevent a human pandemic So far, the only people to come down with bird flu got it from animals. Dr. Jon LaPook reports on how research is underway to keep bird flu from mutating into a form that could spread from person to p...

Nice coverage of our H5 mRNA work by Jon LaPook tonight on @cbseveningnews.bsky.social

www.cbsnews.com/video/the-sc...

Flier for my talk Friday 5/30 at 7 p.m.

Are you a scientist and not sure what to do to help with all the awfulness all around us? Inspired by Vietnam era activism, @standupforscience.bsky.social is hosting a series of "teach ins," in which scientists share a bit about their area of expertise and why it's important with the public. 🧪🦑🌎

Check out this news story that @nature.com wrote describing our recent preprint where we tested our H5 mRNA vaccine in calves.

The data look good and we are currently testing the vaccine in lactating cattle...more to come!

The Nile from the International Space Station:

Once in a while. Good morning Blue Sky

Congratulations!

Spectacular view of 100,000 people attending the #HandsOff march in NYC

Thrilled to share our @elife.bsky.social paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @marisaegan.bsky.social (@cambupenn.bsky.social alum, now faculty @swarthmorecollege.bsky.social)! elifesciences.org/articles/90107 🧵(1/n)

Top FDA Vaccine Official Resigns, Citing Kennedy’s ‘Misinformation and Lies’ (Gift Article) Dr. Peter Marks, a veteran of the agency, wrote that undermining confidence in vaccines is irresponsible and a danger to public health.

Top F.D.A. Vaccine Official Resigns, Citing Kennedy’s ‘Misinformation and Lies’ Gift link: nyti.ms/3DTuvVr

Lab Administration Research Technician- Bertozzi Lab Primary Work Address: Beckman Center, Stanford, CA, 94305-5323 Current HHMI Employees, click here to apply via your Workday account. We are currently looking for a highly motivated Lab Administration ...

We are seeking to hire a lab tech, this is an HHMI funded position, please share the job posting:

hhmi.wd1.myworkdayjobs.com/en-US/Extern...

The difference between Accuracy & Precision.

In a science round table discussion yesterday, my NJ senator @kim.senate.gov suggested a strong argument for NIH and federal funding is global competitiveness. We US-based scientists should start weaving this into our narratives.

Dynamic STING repression orchestrates immune cell development and function Repression of STING expression in neutrophils and T lymphocytes is required for immune homeostasis and tumor response.

'Neutrophils expressed notably low levels of STING, whereas forced expression led to uncontrolled systemic inflammation. During development in the thymus, Tcells dynamically & epigenetically restricted STING expression through DNMT1–mediated transcriptional silencing'
#Immunology

@cp-trendsimmuno.bsky.social Using structure-function information from IFN-γ-binding proteins and biased agonists to uncouple immunostimulatory and immunosuppressive activities
www.cell.com/trends/immun...

The Cost of the Government’s Attack on Columbia American universities have given the country prosperity and security. The Trump administration’s attack on academic freedom endangers all of that.

Today I'm filled with admiration for my university's president, Chris Eisgruber. He's standing up for Columbia and for universities as a home for freedom of ideas, debate, and thought - free of government attack. www.theatlantic.com/ideas/archiv...

My privilege to team up with FASEB President-elect Eric Kelley today. We visited the W. Virginia and #Vermont offices together to explain how science research saves lives, creates jobs and keeps the USA competitive.

#FASEBonTheHill #FundScience #NIH #MedSky #AcademicSky #UVMLarnerMed🧪

UCSF, like all UC campuses, announced an immediate hiring freeze today. UCSF is the second largest employer in the city. There will be wide ripple effects in the Bay Area and beyond, including the future of biotech and pharma in the area. 🧪

If there's one thing that domestic violence research has taught me, it's that abusers set up no-win scenarios. They punish you whether you cooperate with them or whether you push back.

The only way out is to strengthen ties with people outside of the relationship who can create new, better options.

A school photo of a gently smiling teenage girl. She has long brown hair and a black cardigan.

My dear friend’s niece, who in October developed sepsis when a Georgia hospital refused her a D&C after a miscarriage, will be taken off life support tomorrow.

I don’t know the names of the countless others who have suffered and will suffered because of anti-abortion laws.

But her name was Haley.

Dear SMBE Members, I am writing to solicit nominations for SMBE President-Elect, Secretary, Treasurer and 2 Councilors whose terms will begin on January 1, 2026. Each of these positions is for a duration of three years. Council members play important roles in guiding the development of the society, soliciting and implementing programs that support our members, while enriching opportunities for young scientists from around the world. They also have a role in overseeing our two excellent journals (MBE and GBE) as well as our annual meeting, regional meetings, and satellite meetings. Nominations will be reviewed by the nominations committee who will then put forward a slate of two candidates for each position for vote by the SMBE membership. Past and current council members are listed HERE. Nominations (self-nominations are welcome) should consist of a brief statement in support of your suggestion (why this nomination, what the nominee can bring to SMBE, work subject, other biographical information). For Presidential nominees please include previous involvement with SMBE. We ask the nominators to confirm explicitly that the person they are nominating has already confirmed their willingness to run for office. Please send your nominations to Harmit Malik <hsmalik@fredhutch.org> AND to Emmanuelle Lerat <secretary.smbe@gmail.com> by April 18, 2025. We look forward to hearing from you! Sincerely yours, Emmanuelle Lerat Secretary of SMBE, on behalf of the Nominations Committee* *The Nominations Committee is composed as follows: Harmit S Malik (Chair) USA. Xuming Zhou, China. Mary O'Connell, UK. Nicolas Galtier, France. Deepa Agashe, India. Emmanuelle Lerat (ex officio), France.

Please consider nominating deserving colleagues (including yourselves) who would be excellent candidates for five open positions on the Council, including Nominations for President-elect, Secretary, Treasurer, and 2 Councilors.

Please share widely!

@official-smbe.bsky.social

Thank you for writing this🙏

DOGE ends America’s golden age of biomedical research Biomedical research impacts all of us. I became curious about how drugs work after my mom was diagnosed with rheumatoid arthritis when I was a small boy. She received “gold shots” as treatment, which ...

I’m a biomedical researcher who lost his wife to cancer. Finding cures is personal to me. What’s happening at the NIH is devastating. Here’s my editorial in my hometown newspaper.

www.vindy.com/opinion/edit...

Thank you @vvsmider.bsky.social for sharing this story.

Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella PGD2 released after NAIP-NLRC4 inflammasome activation in tuft cells signals onto ILC3s and mediates host defense mechanisms against Salmonella Typhimurium

#WeekendRead! #InflammasomePower! @rauchlab.bsky.social &co show @jem.org that small intestinal tufts cells activate the NLRC4 inflammasome leading to PGD2-dependent IL-22 production by ILC3, protecting against Salmonella!
rupress.org/jem/article/...

Photo from the Economist with quote “Public health is the mom of science - She does everything and no one noticea until she stops doing it”

This 😭
via @economist.com

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Looking for a research assistant post in London? 🤔

Interested in how anti-cytokine auto-antibodies are associated with immune dysfunction and disease during ageing? 🎯

Then do consider applying for this exciting post 👇
#ImmunoSky #IDSky @uclmedsci.bsky.social

www.ucl.ac.uk/work-at-ucl/...

as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech
bsky.app/profile/need...

In my 25 years since high school I’ve seen

1. HIV/AIDS go from death sentence to manageable with drugs

2. Cystic fibrosis go from pretty much an extended death sentence to manageable with drugs

3. Sickle cell go from a horrible disease to (almost maybe) cured by gene therapy

Simply incredible