Shane Gonen's Avatar

Shane Gonen

@gonenshane.bsky.social

Assistant Professor, University of California Irvine. All opinions my own #CryoEM #ProteinDesign #Biochemistry #MembraneProteins #UCI cryoem.bio.uci.edu

1,414 Followers  |  1,020 Following  |  14 Posts  |  Joined: 18.11.2023  |  2.1845

Latest posts by gonenshane.bsky.social on Bluesky

Herculean effort by the Wiles lab @UCIBioSci Congrats to the entire team and the first author postdoc Liz for this amazing cover art! Proud of #Nicholaslab members Naveena and Julio for the small role we played in this groundbreaking work

06.05.2025 17:49 β€” πŸ‘ 16    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out nowβ€”check it out, it’s πŸ”₯! www.nature.com/articles/s41...

06.05.2025 19:17 β€” πŸ‘ 41    πŸ” 14    πŸ’¬ 0    πŸ“Œ 1
Post image

"Phollow" the link to our May issue to read about...

πŸ’₯lysing bacterial pathogens
β›½microbial alkane oxidation
🌱importance of seed-borne bacteria
πŸ™…β€β™€οΈprotective antibodies for norovirus
🚰E. coli in urban drinking water

...and more!πŸ‘‡
www.nature.com/nmicrobiol/v...

06.05.2025 16:19 β€” πŸ‘ 25    πŸ” 5    πŸ’¬ 1    πŸ“Œ 3

Beautiful new work from our colleagues down the hall πŸ”¬πŸ₯‚

19.04.2025 00:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

😳 good to hear you are ok!

19.02.2025 09:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image 13.02.2025 20:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thanks Steve :)

08.02.2025 07:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I - Nature Communications Animal toxins can modulate action potentials and are important leads for therapeutics. Here, the authors use cryo-EM to show the interaction of the tarantula venom peptide Protoxin-I with a human volt...

Our #CryoEM study on the binding of a Tarantula toxin to a full-length human voltage-gated sodium channel has been published. Very proud of the awesome people in my lab πŸ₯³πŸ₯‚

www.nature.com/articles/s41...

07.02.2025 21:00 β€” πŸ‘ 45    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1
Post image

buckle up out there

01.02.2025 21:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Molecular basis of proton sensing by G protein-coupled receptors Three proton-sensing G protein-coupled receptors (GPCRs)β€”GPR4, GPR65, and GPR68β€”respond to extracellular pH to regulate diverse physiology. How proton…

Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs.

Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs

www.sciencedirect.com/science/arti...

02.01.2025 17:35 β€” πŸ‘ 24    πŸ” 11    πŸ’¬ 3    πŸ“Œ 3

Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados!

Feel free to share, add and distribute, so we can come together again! 😍

go.bsky.app/AEeXh86

16.11.2024 03:53 β€” πŸ‘ 125    πŸ” 66    πŸ’¬ 71    πŸ“Œ 7
Post image

I see 2 dolphins and a croc
image from not #cryoem

27.11.2024 23:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Happy Birthday Dequina!

26.11.2024 17:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Hello there :)

25.11.2024 16:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Hello :)

24.11.2024 18:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Hello there :)

21.11.2024 07:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Maybe a heat shock protein. Like 1E94. Plenty of options though

21.11.2024 04:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image

#cryoem grids don't have to be 3mm do they?

19.11.2024 23:23 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Here is a starter pack for CryoEM/ET enthousiasts
To be completed
go.bsky.app/JmQksC

08.11.2024 22:01 β€” πŸ‘ 110    πŸ” 76    πŸ’¬ 73    πŸ“Œ 6

Hello there :)

13.11.2024 17:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@gonenshane is following 20 prominent accounts