Santiago Perez Patrigeon, MD, PhD

Angiostrongylus

Next draft Infection Card for Epipocalypse: Bug Detectives: Angiostrongylus!

Don't stick raw snails, crustaceans, or frogs into your mouth. Snail slime is problematic too.

#IDSky #MedSky #EpiSky any feedback or suggestions?

Permethrin-Treated Baby Wraps for the Prevention of Malaria | NEJM Malaria remains a major cause of childhood death in sub-Saharan Africa. We leveraged the traditional practice of mothers carrying children on their backs in cloth wraps to assess whether treating t...

Ever since I learned about this study enrolling I have been eagerly awaiting the results. Researchers in Uganda took a centuries-old cultural practice mothers carrying babies on their backs in cloth wraps and turned it into a public health tool. You got to love it!
www.nejm.org/doi/full/10....

State-of-the-Art Review: Hepatitis C Abstract. Hepatitis C virus (HCV) infection remains a major cause of chronic liver disease and premature mortality worldwide. The World Health Organization

State-of-the-Art Review: Hepatitis C

#IDSky

CSF testing for suspected neurosyphilis

➡️isolated ocular or otic features: LP not needed

➡️CSF VDRL: specific but not perfectly sensitive
➡️CSF treponemal test: high negative predictive value, for cases with high suspicion despite negative CSF VDRL

doi.org/10.1002/ana....

#IDSky

#idboardreview mail sorter recently exposed to unknown powder in envelope and now in ICU with respiratory distress, widened mediastinum, blood cultures gram
Positive rod. What #isolation precaution is needed? #idmeded #meded #idsky #idfellows #IPsky

Another nail in the coffin of ABC? (and AZT btw) 😅

HIV resistance to dolutegravir varies with co-administered agents We hypothesized that HIV-dolutegravir-resistance is more frequent when co-administered with nucleos(t)ides with shorter intracellular half-lives.

HIV resistance to dolutegravir varies with co-administered agents

✅ Just Accepted
#IDSky

https://bit.ly/4n0HvtF

What a pleasure to finally meet @santymd.bsky.social - in Banff, no less - where we are both speaking at the Alberta Society of ID annual meeting #idsky

Emory University to discontinue its DEI programs, offices Emory had previously embraced diversity efforts, but interim president Leah Ward Sears wrote that the decision was due to federal laws and mandates.

I'm not proud of this

@germhuntermd.bsky.social

Illan schwartz

I am starstruck!!!

Must read for all teams consulting infectious diseases #idsky #idmeded #meded #stewardship #voicesofID @cidjournal.bsky.social
academic.oup.com/cid/advance-...

Effectiveness of the TAK-003 dengue vaccine in adolescents during the 2024 outbreak in São Paulo, Brazil: a test-negative, case–control study TAK-003 was effective against symptomatic dengue and hospitalisation with dengue in adolescents during a large outbreak caused predominantly by dengue virus serotypes 1 and 2. These findings underscor...

Dengue vaccine effectiveness during outbreak in adolescents - 50.2% after first dose, 61.7% after 2nd dose, also protective against hospitalization. Protection waned to 49.7% by 90 days. For outbreak intervention, decline may be less meaningful… #IDSky

www.thelancet.com/journals/lan...

CAHR welcome poster

Very excited to be here!

Antibiotic prophylaxis in injury: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document

A super useful set guidelines for abx prophylaxis in trauma that came out last year which I missed:

pmc.ncbi.nlm.nih.gov/articles/PMC...

Written by trauma surgeons with many common injuries that DON’T require ppx or alternatively ppx <48 hours

#IDSky

New #MonkeyPox variant clade Ib recently spread outside Congo with demographic shift - higher case fatality rates for younger people.

The #WesternPacific & #SoutheastAsia have high endemic burden. Are we ready for strategy planning against clade Ib? 🦠

Viewpoint👉 tinyurl.com/yh579kbh #IDSky #MedSky

1h49 très bien!!! 👊👊👊

Layoffs begin at Atlanta-based CDC, other US health agencies The layoffs include 2,400 jobs at the CDC.

Several colleagues at the CDC are waking up this morning to emails notifying them they are no longer employed. A cruel purge that will cripple the agency and its mission of protecting public health.
I stand with public health.
www.wsbtv.com/news/local/l...

Agree 100%! I’ve seen a few of those in PLHIV 😉👍

Two More People May Be Cured of HIV After Stem Cell Transplants One experienced viral rebound after an initial treatment interruption but remains in remission after stopping antiretrovirals a second time.

Two more cases of HIV cure after stem cell transplant - the 8th and 9th.
The treatment is too dangerous and gruelling for anyone not facing a terminal cancer diagnosis but each case may provide clues to a cure for all.
@lizhighleyman.bsky.social reports from #CROI2025.
www.poz.com/article/two-...

What was childhood like before vaccines? The anti-vax movement has gone mainstream, but before these shots, grief and loss marked the lives of children.

"In the 19th century, it was incredibly dangerous to be a child.

As of 1900, about 18 percent, or nearly one in five, American children died before their fifth birthday. ..."
What changed? Better sanitation, medical advances - and vaccines. www.vox.com/health/40268...

Gender equality doesn’t just 'happen.'

Women’s rights must be fought for and protected.

Our responsibility is clear.

To lead by example and create a world where opportunities are fair for all.

Not just today, but every single day.

#InternationalWomensDay

Buenos días

Family includes everyone! ❤️

What if We Can't Rely on PubMed? - Absolutely Maybe PubMed is incredibly reliable. And a lot depends on it. It’s an ecosystem built around MEDLINE, the steady feed of new publications…

It's not a mirror - it's not PubMed with the same functionalities at a different URL. It's a quite different and independent service, with different search algorithms etc, that ingests PubMed/PMC. See my post: absolutelymaybe.plos.org/2025/02/14/w...

a woman in a dark room with the words " my inside voice " below her Alt: a woman in a dark room with the words " my inside voice " below her

Let me say it as loud as I can so they can hear me all the way to the back of the room:

GPC in a Gram stain from a sputum is NOT an indication to start Vancomycin!!!!!!

Did the threshold to treat decrease? If I remember correctly previous guidelines still recommended observation in SAg neg patients with chemoTx. What do you think?

Text from my friend Diane about her unpleasant bout with norovirus

So many people either have had norovirus recently, or have asked me about it, that I summarized some key points.

Though it's incredibly common, in many ways it's amazing it isn't even *more* common.

More on this misery inducing virus here. #IDSKy blogs.jwatch.org/hiv-id-obser...

Effectiveness of Pfizer’s RSV vaccine could reduce disease burden in older adults The bivalent respiratory syncytial virus prefusion F, or RSVpreF, vaccine may prevent one hospitalization or ED visit tied to the infection for every 250 vaccinated older adults, an analysis showed.Th...

Pfizer’s RSV Vaccine Could Reduce Disease Burden In Older Adults

#IDSky
#RSV

www.healio.com/news/primary...

Six Childhood Scourges We’ve Forgotten About, Thanks to Vaccines Most Americans, including doctors, have no memory of the devastating diseases that routinely threatened children until the 1960s.

Most Americans, including doctors, have no memory of the devastating diseases that routinely threatened children until the 1960s. https://buff.ly/41DSpxr #Vaccines #InfectiousDiseases #PediatricHealth