Karges Group

Proud to share our new @ChemRxiv preprint. We report on a novel Metal-to-Metal Electron Transfer Mechanism enabling Hydroxyl Radical Photoredox Catalysis in Hypoxic and Drug-Resistant Cancer Cells, addressing bottlenecks in photodynamic therapy. Please RT! chemrxiv.org/engage/chemr...

Check out our paper in @chemcomm.rsc.org about the Red-Light Excitation of Ru(II)-Pt(II) Tetranuclear Complex for Combined Photoactivated Chemotherapy and Photodynamic Therapy. Congrats to Pia, Eleni, Julia, and @nmontesdeocas.bsky.social ! @ruhr-uni-bochum.de dx.doi.org/10.1039/D5CC...

🚨 PhD Opportunity! 🚨
Join our group in Bioinorganic Chemistry to work on the synthesis & biological evaluation of metal complexes for anticancer therapy.
jobs.ruhr-uni-bochum.de/jobposting/8...

Check out our paper in @inorgchemfront.rsc.org about the Induction of Oncosis by Light Activation with an Ir(III) complex conjugated to Albumin. Congrats to Antonio, Zisis, and Lisa. Fantastic collaboration with @joseruizlab.bsky.social ! @ruhr-uni-bochum.de @um.es dx.doi.org/10.1039/D5QI...

Sterbende Tumorzellen machen Metastasen zur Zielscheibe Ein neuer Wirkstoff kann Krebszellen beseitigen und gleichzeitig das Immunsystem trainieren, solche Zellen überall im Körper zu vernichten.

👉 Ein von der @kargesgroup.bsky.social an der @ruhr-uni-bochum.de entwickelter neuer Wirkstoffkomplex tötet Krebszellen auf eine so geschickte Art, dass sie im Sterben dem #Immunsystem den Weg zu #Metastasen zeigt, die sich an entfernten Orten im Körper entwickeln.

Thanks Maniklal!

Check out our paper in J. Med. Chem. @acsbiol.bsky.social @acsmedi.bsky.social about the induction of immunogenic cell death by a gallium complex for chemoimmunotherapy. Congrats to Zisis and Yassin! @ruhr-uni-bochum.de
dx.doi.org/10.1021/acs....

Honored to be giving the plenary lecture for the Inorganic Devision at the Brazilian Chemistry Conference #48RASBQ

Wonderful presenting some of our research at Universidade Federal de Juiz de Fora @ufjfoficial.bsky.social Thanks to Luiz for the kind invitation! @ruhr-uni-bochum.de

Check out our study in @acsmedi.bsky.social about the "Induction of Cuproptosis with a Highly Cytotoxic Tripodal Cu(II) Complex". Congrats to Ricarda and @nmontesdeocas.bsky.social @ruhr-uni-bochum.de
pubs.acs.org/doi/abs/10.1...

Wonderful presenting some of our studies at the BioOpen Conference in beautiful Łódź as part of the UNIC network. @ruhr-uni-bochum.de

Check out our paper in @inorgchemfront.rsc.org about Utilizing Metal-Metal Electron Transfer in Dinuclear Photosensitizers for Exceptionally High ROS Production. Congrats to @juansanzvi.bsky.social @nmontesdeocas.bsky.social ! Wonderful collaboration with Gustavo Espino! dx.doi.org/10.1039/D5QI...

Time for a new group picture 😉

Thanks Conchita!

Check out our article in ACS Med. Chem. Lett. @acsmedi.bsky.social about the Induction of Ferroptosis with Au(I) NHC Complexes. Congrats to @nmontesdeocas.bsky.social . Great collaboration with Thomas Scattolin! @ruhr-uni-bochum.de dx.doi.org/10.1021/acsm...

Check out our Article in @daltontrans.rsc.org about the Synthesis and Photophysical Evaluation of an Aldehyde Bearing Ru(II) Complex as a Synthetic Precursor for Photodynamic Therapy. Congrats to Lisa, Hung, Nicolas, Zisis, and Eun! dx.doi.org/10.1039/D5DT...

Congrats to Pia @psiekierski.bsky.social for receiving the Poster Award of the 19th Ferrocene Colloquium! 🎉

Wonderful welcoming you to Bochum and thanks for a fantastic presentation about recent progress in PDT!

Thanks Maniklal!

Check out our article in J. Med. Chem. @acsmedi.bsky.social about the Rational Design of an Ir(III) Complex with Exceptionally Strong Human Serum Albumin Binding for Photodynamic Therapy. Congrats to Antonio & Lisa! Wonderful collaboration with @joseruizlab.bsky.social ! pubs.acs.org/doi/full/10....

Das ist Schade, aber viel Spaß in Mainz. Gerne, können wir morgen besprechen. 😉

Kannst gerne das nächste Mal in Bochum vorbei kommen. Du bist herzlich eingeladen. Noch eine schöne Nacht und bis Morgen.

Ich komme erst morgen früh. Viel Spaß in Münster!

Congrats Pepe!

A novel benzothiazole-1,2,3-triazole-based arene osmium(II) complex as an effective rhabdomyosarcoma cancer stem cell agent We designed a series of pseudo-octahedral arene Os(ii) complexes (Os1–Os5) with the general formula [(η6-p-cym)Os(BTAT)Cl]+, where BTAT represents chelating N^N′ ligands based on the 1-aryl-4-benzothi...

A novel arene osmium(ii) complex as an effective rhabdomyosarcoma cancer stem cell agent - now published in InorgChemFront in collaboration with Viktor Brabec pubs.rsc.org/en/content/a... Congrats to all the co-authors.

High‐Throughput Combinatorial Metal Complex Synthesis This minireview explores advancements in high-throughput combinatorial synthesis of metal complexes, emphasising their applications in catalysis, drug discovery, and materials science. We highlight v...

Our Minireview on the growing field of combinatorial metal complex synthesis is now out! onlinelibrary.wiley.com/doi/full/10....

Congrats!

Wonderful seeing our cover on the recent issue of @daltontrans.bsky.social ! Check out the full article here: dx.doi.org/10.1039/D4DT...

Congrats Sebastian!

I am so so sorry reading this. My condolences to the BabakGroup, Victor's friends and family! RIP.