Junjie Guo

RNA Club | March 2026

Come support our trainees and engage in discussion across RNA disciplines

📅 Tuesday, March 10
⏰ 9:00 AM
📍 Bass 305, Science Hill

Coffee & bagels provided

Open to Yale and affiliated institutions

Congratulations to Dr. Lianhuan Wei in the lab for winning a poster award at the Gordon conference on FTD and related dementias! @yaleneuro.bsky.social @yalerna.bsky.social

Amazing! Congratulations Cate!

Congrats Jimmy! You're on a roll!

Amazing! Congrats!!

Happy Birthday! 🎉

That never stopped a certain family in the WH

Color photograph of Joan Steitz (Joan Argetsinger Steitz), the distinguished American molecular biologist and biochemist renowned for her groundbreaking discoveries in RNA biology, including the identification of small nuclear ribonucleoproteins (snRNPs) essential to RNA splicing. She is pictured in a close-up portrait within a laboratory or research setting, smiling warmly and directly at the camera with an engaging, approachable expression that conveys enthusiasm and expertise. Steitz has gray hair pulled back, striking blue eyes, and is wearing large, elaborate dangling earrings adorned with purple gemstones and metallic accents. She is dressed in a rich purple blouse. The softly blurred background includes scientific elements such as lab benches, equipment, monitors, charts, and partial signage, evoking the environment of her long career at Yale University where she served as Sterling Professor of Molecular Biophysics and Biochemistry. #JoanSteitz #MolecularBiology #WomenInScience #Biochemistry #RNA

Biochemist/molecular biologist Joan Steitz was born #OTD in 1941.

She (& team) figured out how our cells read/use genetic instructions to make proteins. A key person who helped crack the code on RNA—the molecule that acts like a messenger between DNA & and the proteins our bodies need. #WomenInSTEM

Congratulations Cate!

Check our latest collaboration with the Kleaveland Lab (kleavelandlab.org), led by Joanna Stefano and Lara Elcavage: academic.oup.com/nar/article/... (1/2)

Excited to publish our work on how mutations in the muscle-specific ribosomal protein RPL3L drive severe heart disease. This is Part I of a larger body of work led by Michael - stay tuned for Part II on how specialized ribosomes function in normal physiology www.nature.com/articles/s44...

Awesome! Congratulations Xuebing!

The Wu Tsai Institute at Yale University is hiring!

Two faculty searches are now open for neurocomputation and neurodevelopment. If you are at #SfN25, visit booth #3724 to learn more.

wti.yale.edu/opportunities

#KnowTogether #ScienceAtYale

TDP-43 loss brings RNA to a twist ending - Nature Neuroscience In amyotrophic lateral sclerosis (ALS), nuclear depletion and cytoplasmic aggregation of the RNA-binding protein TDP-43 cause widespread dysregulation of mRNA splicing. Two recent studies have now rev...

New article @natneuro.nature.com by @yaleneuro.bsky.social Suzhou Yang & @kavliatyale.bsky.social Postdoc Fellow @zhenlei.bsky.social, highlighting studies by @frattalab.bsky.social Gitler & La Spada labs on the role of TDP-43 on mRNA 3' end in ALS @yalerna.bsky.social www.nature.com/articles/s41...

Oxidative stress sensing by the translation elongation machinery promotes production of detoxifying selenoproteins Selenocysteine, incorporated into polypeptides at recoded termination codons, plays an essential role in redox biology. Using GPX1 and GPX4, selenoenzymes that mitigate oxidative stress, as reporters,...

Colliding ribosomes are potent signals of cellular stress. But do cells use ‘programmed’ ribosome collisions to regulate gene expression? I’m excited to present a new story from my lab led by Frederick Rehfeld(@fred-rehfeld.bsky.social) which revealed that the answer is YES! Read on to find out how👇

mRNA poly(A)-tail length is a battleground for coronavirus–host competition Most eukaryotic mRNAs contain a poly(A) tail, which in post-embryonic cells enhances their stability. Many cytoplasmic RNA viruses also harbor poly(A) tails on their genomic RNA and mRNAs. Here, we re...

Check out the latest work from our lab, led by Arash Latifkar @ara-latifkar.bsky.social , www.biorxiv.org/content/10.1...

Poster with QR code linking to the position

I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...

入我画竹影，入我网蜻蜓。_哔哩哔哩_bilibili -, 视频播放量 1351、弹幕量 0、点赞数 157、投硬币枚数 20、收藏人数 34、转发人数 5, 视频作者 懒云居画, 作者简介 国画｜收藏/合作邮箱lanyunjuhua@163.com，相关视频：莫使金樽空对鹤，且放白鹿青崖间，须行即骑访名山。，夏日荷仙走进国画，采荷遇白鹿，国画采莲，乘叶秋游，携鹤伴松风，梦里不知身是鹤，闲云野鹤，春去秋来

Also check out this video from the artist showing the creative process: www.bilibili.com/video/BV1eKK...

Excited to see this beautiful art, commissioned from the Chinese artist 懒云居画 (@subaiweipainting on Instagram), on this month's cover of Nature Neuroscience! @natneuro.nature.com @yaleneuro.bsky.social @yalerna.bsky.social @kavliatyale.bsky.social @wutsaiyale.bsky.social

Congratulations Sinha lab!

Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD - Nature Neuroscience By selectively isolating and sequencing the rare RNA transcripts containing C9orf72 repeat expansion from ALS–FTD neurons, the authors uncover an alternative splicing mechanism that explains the reten...

Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD

@junjieguo.bsky.social @yalerna.bsky.social @yaleneuro.bsky.social

www.nature.com/articles/s41...

Human RNome Project Our mission is to advance RNA science to impact human health, food security and boost biomanufacturing.

But have you heard of the "RNome"? humanrnomeproject.org

Thank you Adam!

‘A tipping point’: An update from the frontiers of Alzheimer’s disease research In a Q&A, Yale neuroscientist Amy Arnsten discusses the state of Alzheimer’s disease research, exciting treatment breakthroughs on the horizon, and the key role of NIH funding in making it all happen.

Amy Arnsten, PhD, Albert E. Kent Professor of Neuroscience @yaleneuro.bsky.social, shares in an interview the current state of Alzheimer's research, where the field is going, and the importance of NIH funding to keep making progress towards treatments.

Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD Nature Neuroscience - By selectively isolating and sequencing the rare RNA transcripts containing C9orf72 repeat expansion from ALS–FTD neurons, the authors uncover an alternative splicing...

Read it here: rdcu.be/eAcNv

Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD - Nature Neuroscience By selectively isolating and sequencing the rare RNA transcripts containing C9orf72 repeat expansion from ALS–FTD neurons, the authors uncover an alternative splicing mechanism that explains the reten...

Excited to see the work by @Yale_INP student Suzhou Yang w/ collabs @yaleneuro.bsky.social iPSC core @jdpereira.bsky.social and @mayoclinic.org @gendron_tania on #C9orf72 #ALS & #FTD finally out in @natneuro.nature.com! @wutsaiyale.bsky.social @kavliatyale.bsky.social www.nature.com/articles/s41...

Congrats!!

Nicely said. I'd also add that not knowing is equally exciting!

Congratulations 2025 Gilliam Fellows and Advisors! 🎉

The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.