Florentin Lab

An exciting collaboration with @orafurman.bsky.social from Hebrew U and Steve Johnson from Indiana U. 👭
Work supported by ISF, Abisch-Frenkel Lectureship, Kuvin foundation and STEP scholarship. 💲
Manuscript thoroughly reviewed and thus much-improved.
Thank you all!!!🤗🙌🙏🪷

A chaperonin complex regulates organelle proteostasis in malaria parasites Author summary The cell of the human malaria parasite Plasmodium falciparum has a unique organelle called the apicoplast that produces essential metabolites, but it is unclear how it maintains a stabl...

Please check Amanda’s new publication, fresh on PLOS Pathogens! 😀👩‍🔬🧪🧬
Read & learn about organelle proteostasis in malaria parasites -
An apicoplast-biogenesis mutant that dies on the first cycle🩸
BIG complexes and drug targets 💊💉
journals.plos.org/plospathogen...

An Essential Adaptor for Apicoplast Fission and Inheritance in Malaria Parasites Blood-stage Plasmodium falciparum parasites rely on a non-photosynthetic plastid, the apicoplast, for survival, making it an attractive target for antimalarial intervention. Like the mitochondrion, th...

🚨 New preprint alert! 🚨
We’ve uncovered a key player in malaria parasite cell division—meet PfAnchor, the first apicoplast-specific dynamin adaptor protein! Check the thread below 🧵for more details. #U_ExM #Malaria #Apicoplast
www.biorxiv.org/content/10.1...

תודה לך 😊

What an interesting and personal reflection of women, science and society. And how about the yet-unfulfilled role of women in conflict resolution? One must fight for better days

Can't think of a better response! Please reach out via email (anat.florentin@mail.huji.ac.il) and we can also host you during lab meeting - we love having curious guests!

Thank you and we are here to hear your thoughts 👩‍❤️‍💋‍👩

The brave heroines of this saga are Michal (left), the most gifted – and stubborn!- microscopist one can imagine, and princess Alia (right) who is never shy of staying overnights to follow parasites quirky replication! What an inspiration these two are in our lab and communities! ❤️

Organelle Development and Inheritance are Driven by Independent Nuclear and Organellar Mechanisms in Malaria Parasites The apicoplast organelle of Plasmodium falciparum is essential for parasite replication, however the details of its biogenesis, inheritance and regulation throughout the cell cycle are unknown. Here, ...

Another exciting preprint from our new lab‼️
Are you interested in Parasites 🦠 + Organelle biology 🧪+ Microscopy 🔬+ Cell Cycle 🧬?!
How could one not be?! 👩‍🔬
Check out, read & comment and wish us good luck with the long way ahead towards publication…
www.biorxiv.org/content/10.1...

Molecular Parasitology Community The MPM XXXVI website is now online

The MPM XXXVI page is now live. Sept 14th to Sept 18th. More updates will be coming soon. Check it out on the parasitesrule.com website. Organized this year by Richarch McCulloch @rmc9z.bsky.social, Photini Sinnis, Marc-Jan Gubbels, Deepali Ravel & Omar Harb @omarharb.bsky.social

Registration for the 2nd WiM online conference is now OPEN, everyone can register: womeninmalaria.es/wim-conferen...

There is a fee waiver application for LMICs & also an option to buy fee waivers for others during the registration process 🧫🧬🦟 Please share!

People sometimes make fun of science that sounds stupid and random.

Meanwhile, a study of lizard saliva turned into a peptide medication, which was turned into a diabetes medication, which was turned into a GLP1 weight loss drug, that just became the first therapy every approved for … sleep apnea

I am looking for an ERC-funded postdoc to work on spatial proteomics of microalgae (red algae and glaucophytes). The ideal candidate will have experience with mass spec and data analysis (R), but above all a keen interest in broad eukaryote evolution and protists #protistsonsky (1/2)

A thread of 9(!!) #Parasitology-based, funded PhD opportunities from the EastBio doctoral training programme at Edinburgh Uni listed below! The projects include #malaria/#Plasmodium, #trypanosoma, #leishmania, #toxoplasma, and #helminths! All deadlines are the 17th January 2025!

😆 Hyperexcited to see the program!
Interested in apicomplexan parasites? 🔬What a lineup of speakers👩‍⚕️👨‍🔬 + registration is affordable 💰 and low on carbon footprint 👣 apicomplexaconference.com

An exciting collaboration with
@orafurman.bsky.social from Hebrew U and Steve Johnson from Indiana U. Work supported by ISF, Abisch-Frenkel Lectureship, Kuvin foundation and STEP scholarship. Thank you all!!! 🤗🙏🏽🌸😁

Beware - this angry bird (sorry, parasite!) is looking your way
(blue nuclei, yellow apicoplast, red cytoplasm)

Hey likeminded colleagues with high standards and low budget! Looking for a super-fun, low-cost lab social activity? Our paint-your-lab-coat-day was a HUGE SUCCESS:

Although we expect a long and tedious road until acceptance, that first big submission felt like something!

Although we expect a long and tedious road until acceptance, that first big submission felt like something!

Malaria research in Israel?! You read that right! From the blog of Kobi Russell at The Times of Israel

Motivated🙋, kind🥰 and hardworking👩‍⚕️, Amanda's and Shirly's joint STEP scholarship is well-deserved! 🔬🥼. The Science Training Encouraging Peace program funds pairs of Israeli and Palestinian students 👩‍❤️‍💋‍👩 Do you also feel that any positive news could be nice? 👇👇👇
blogs.timesofisrael.com/malaria-rese...

Hepcidin: A missing link at the interface of malaria and hypertension Malaria and hypertension are seemingly unrelated communicable and non-communicable diseases, both highly pervasive in the global south. There is a deb…

Is there a single molecule ⚛️ linking malaria to high blood pressure??? ⚕️📢💉👨‍🔬 Happy to work with and learn from lab trainee Dr. Hari Shankar 🤩 Together, we thought, explored and investigated concepts that are pretty distinct from our daily lab work🔬:
sciencedirect.com/science/arti...

A Chaperonin Complex Regulates Organelle Proteostasis in Malaria Parasites The apicoplast of Plasmodium parasites serves as a metabolic hub that synthesize essential biomolecules. Like other endosymbiotic organelles, 90% of the apicoplast proteome is encoded by the cell nucl...

🚨🖨️👩‍🔬New Preprint alert! Please have a look to learn about organelle proteostasis in malaria parasites🩸 An apicoplast-biogenesis mutant that dies☠️on the first cycle! 🧪🦟So proud in 1st author Amanda Tissawak for the first major research article from our lab!
www.biorxiv.org/content/10.1...