François Mayer

Our December issue is out!

www.nature.com/nmicrobiol/v...

The image shows a female Asian tiger mosquito cadaver covered by mycelium (white) following infection with spores of an engineered Metarhizium strain. Parts of the mycelium produce spores (green) that can again attract and kill mosquitoes.

Our final issue of 2025 has gone live!

🫁pertussis prevention
🏭pollutants and gut bacteria
🕳️porins and resistance in E. coli
🧬many flavours of CRISPR
🦟fatal fungal attraction

...and more 👇
www.nature.com/nmicrobiol/v...

🚀 New journal alert!
We are Communications AI and Computing: an open access space from @natureportfolio.nature.com for research in AI, ML, and computational science.

Now open for submissions!
www.nature.com/commsaicomp/

#AI #ML #OpenAccess #ComputationalScience #NaturePortfolio #Research

Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus - Nature Microbiology Florfenicol amine hijacks intrinsic resistance in Mycobacterium abscessus, highlighting that antimicrobial resistance mechanisms can be harnessed for antibiotic activation.

Out now in Nature Microbiology 👀

www.nature.com/articles/s41...

Genetic population structure of Haemophilus influenzae at local and global scales - Nature Microbiology Large-scale sequencing and population genomic analyses reveal frequent transmission, a highly admixed global population structure and evidence of pervasive negative selection in Haemophilus influenzae...

Out recently in Nature Microbiology👇

www.nature.com/articles/s41...

Our November issue is out now:

www.nature.com/nmicrobiol/v...

Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes - Nature Microbiology Insects colonized with Metarhizium fungi emit longifolene to lure new hosts for infection to disperse spores. A fungal strain was engineered to emit longifolene to attract and eliminate mosquitoes.

OUT NOW! - Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes 🍄🧲🦟☠️

By Dan Tang, Jun Cao, Raymond Leger, Jianhua Huang, Weiguo Fang & colleagues.

www.nature.com/articles/s41...

Isolation, engineering and ecology of temperate phages from the human gut - Nature Human host-associated cellular products may act as induction agents for bacteriophages.

Very excited to share the latest work from our lab, which was published today in Nature!
nature.com/articles/s41...

PhD graduate and now post-doc Sofia Dahlman, along with co-senior author Sam Forster from The Hudson and other researchers from our lab and others.

Isolation, engineering and ecology of temperate phages from the human gut - Nature Human host-associated cellular products may act as induction agents for bacteriophages.

Isolation, engineering and ecology of temperate phages from the human gut

Out now in Nature, by Sofia Dahlman, Jeremy Barr & colleagues. @jeremyjbarr.bsky.social

#microsky

www.nature.com/articles/s41...

Discovery and artificial intelligence-guided mechanistic elucidation of a narrow-spectrum antibiotic - Nature Microbiology Enterololin is a narrow-spectrum antibiotic that selectively kills Enterobacteriaceae in vitro and in a mouse model of adherent-invasive Escherichia coli gut infection. AI-guided mechanism-of-action s...

Discovery and artificial intelligence-guided mechanistic elucidation of a narrow-spectrum antibiotic

By Denise Catacutan, Jon Stokes & colleagues.

#microsky

www.nature.com/articles/s41...

A generative artificial intelligence approach for the discovery of antimicrobial peptides against multidrug-resistant bacteria - Nature Microbiology This study presents a generative artificial intelligence approach for the high-throughput discovery of antimicrobials against multidrug-resistant bacteria.

A generative artificial intelligence approach for the discovery of antimicrobial peptides against multidrug-resistant bacteria

By Yihui Wang, Guoping Zhao, Lei Zhang & colleagues.

#microsky

www.nature.com/articles/s41...

Toxoplasma gondii VIP1 mediates parasitophorous vacuole–host endoplasmic reticulum interactions to facilitate parasite development - Nature Microbiology Toxoplasma gondii forms membrane contact sites with the endoplasmic reticulum of the host cell to facilitate the transfer of biomolecules to its vacuole.

Toxoplasma gondii VIP1 mediates parasitophorous vacuole–host endoplasmic reticulum interactions to facilitate parasite development

By Julia Romano, Isabelle Coppens & colleagues.

#microsky

www.nature.com/articles/s41...

Our October issue is out now!

The images are negatively stained electron micrographs taken from archaella bundles isolated from the archaeon Sulfolobus acidocaldarius.

Check the issue out here:
www.nature.com/nmicrobiol/v...

Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.

OUT NOW: Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections

By Dinesh Subedi, Jeremy Barr & colleagues @jeremyjbarr.bsky.social

www.nature.com/articles/s41...

Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.

Excited to annouce the latest research published by our lab, which is led by Dinesh Subedi and is out today in Nature Microbiology.

www.nature.com/articles/s41...

Deep-mining the archaeal proteome for antibiotics Nature Microbiology - A deep-learning algorithm unravels a collection of archaeasins, peptides from the archaeal proteome with potential antimicrobial activity and implications for the development...

Deep-mining the archaeal proteome for antibiotics

News & Views by Rafael Laso-Pérez

@gecko1990.bsky.social @delafuentelab.bsky.social

Read it here: rdcu.be/eHNwa

Delighted to review the latest findings on how malaria parasites get into our blood cells and how we might stop it!

September issue out now:

Read it here:
www.nature.com/nmicrobiol/v...

Aspergillus fumigatus reference strain Af293 carries a mycovirus that boosts heat+oxidative stress resistance and infection fitness. 😲💥

I encourage you to check out Neta's thread and I'm delighted my group could play a small role in this exciting study!!

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

Out now in Nature Microbiology, by Marina Rocha, Vanda Lerer, John Adeyemi Adeoye, Amelia Barber, Neta Shlezinger & colleagues

www.nature.com/articles/s41...

Our August issue is now live - a special focus issue on ‚Strategies to overcome infectious disease‘

Read it here:

www.nature.com/nmicrobiol/v...

The food-associated resistome is shaped by processing and production environments - Nature Microbiology Whole-metagenome sequencing of 1,780 raw-material, end-product and surface samples from 113 food processing facilities reveals the occurrence of antimicrobial resistance determinants in foods and thei...

#NewResearch

'The food-associated resistome is shaped by processing and production environments' by @nmquijada.bsky.social and co-workers.

#MicroSky 🦠

www.nature.com/articles/s41...

Evolution of antifungal resistance in the environment Nature Microbiology - This Review discusses the evolution, emergence and expansion of environmental fungicide and antifungal drug resistance.

Evolution of antifungal resistance in the environment

New Review Article by @normanvanrhijn.bsky.social and @drjorhodes.com

Read it here: rdcu.be/eyobz

www.nature.com/articles/s41...

Evolution of antifungal resistance in the environment - Nature Microbiology This Review discusses the evolution, emergence and expansion of environmental fungicide and antifungal drug resistance.

A little holiday news:

Evolution of antifungal resistance in the environment www.nature.com/articles/s41...

This started out as a little thought way back in early 2024 between @normanvanrhijn.bsky.social and I, and turned into a full on review! We hope it proves useful to the community.

Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites Zhang, Todeschini, and Wu et al. show that the bacterial defense system Kiwa senses phage attachment at the membrane and assembles a transmembrane complex that halts infection by blocking phage DNA re...

Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription.

www.cell.com/cell/fulltex...

Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.

Fighting malaria as a patient and scientist - Nature Microbiology Fitsum Tadesse was infected with malaria as a young child in Ethiopia and faced challenges to access efficacious treatment during a time of widespread drug resistance. Today, as a scientist in Africa,...

Fighting malaria as a patient and scientist – new Microbe Matters by Fitsum Tadesse out now! #malaria #MicroSky

www.nature.com/articles/s41...

Found: a human gut microbe that makes cancer therapy more effective in mice Cancer therapies called checkpoint inhibitor drugs, which ratchet up the immune system, work better when this bacterium is around.

A potent bacterium in the human gut can supercharge the effects of some cancer drugs

go.nature.com/4lqaBBI

Scientists hide messages in papers to game AI peer review Some studies containing instructions in white text or small font — visible only to machines — will be withdrawn from preprint servers.

This is quite astonishing - Scientists hide messages in papers to game AI peer review

Read this to find out how much you can fit into a single space after a full stop (if you use a very small font)

🧪 #AcademicSky

www.nature.com/articles/d41...

Giardia-induced Type 2 mucosal immunity attenuates intestinal inflammation caused by co-infection or colitis in mice - Nature Microbiology A host–protist interaction regulates mucosal immunity to promote parasitism which also reduces the risk of inflammatory-driven pathologies of the gut.

#NewResearch out now!

Giardia-induced Type 2 mucosal immunity attenuates intestinal inflammation in mice

#microsky

www.nature.com/articles/s41...