Holly Sullivan-Toole

This is really cool!!

In this paper www.nature.com/articles/s41..., we found anhedonia measures were assoc with an in-lab, induced "sunburn", even when controlling for 'skin type spectrum score', sex, age, & minority status. Cutaneous erythema (like sunburn) is also linked to NLRP3 inflammasome!

I’m so sorry you are dealing with this. The fact that junior people have to ghost write grants speaks to how messed up the system is. I really hope the senior people do the right thing here.

anyone got any advice on the following situation? I wrote and did a big chunk of the admin for a large MRC grant which also also awarded. I am named in the Staff breakdown on the grant as "researcher co-lead" with 100%FTE, and I am mentioned by name as "postdoctoral researcher Maria Niedernhuber"

This is really cool!!

In this paper www.nature.com/articles/s41..., we found anhedonia measures were assoc with an in-lab, induced "sunburn", even when controlling for 'skin type spectrum score', sex, age, & minority status. Cutaneous erythema (like sunburn) is also linked to NLRP3 inflammasome!

Psoriasis-related neuroinflammation disrupts thalamostriatal signalling driving anhedonia in both humans and mice Inflammation is implicated in 25% of depression cases, yet limited access to human brain for mechanistic studies and scarce translational models have hindered the identification of neural circuits lin...

Final #neuroskyence preprint of the year! We updated our big neuroinflammation project, studying psoriasis-like inflammation in both humans and mice. Main take-home: we see impaired thalamostriatal signalling in humans and mice alongside depression / anhedonia.

www.biorxiv.org/content/10.1...

The one where they tune a harp? Nevermind 😆

Me & my husband have been planning to do this!!! We have the CDs but not the tower or player—would love to hear them all again!!

“.. Last year, the percentage of H-1B-sponsored doctors in rural counties was nearly twice the share in urban ones ..”

@washingtonpost.com
www.washingtonpost.com/health/2025/...

This afternoon, I was in a meeting with Jay Bhattacharya, and I can confirm this is *exactly* what he both wants and will be doing.

THIS IS NOT HYPERBOLE.

#RewardSignals

Excited to use my first post to share our new paper and my first first-authorship! "Linking reinforcement learning, working memory, and choice dynamics to age and symptoms of anxiety and depression in adolescence" in Developmental Cognitive Neuroscience 🎉https://doi.org/10.1016/j.dcn.2025.101626

The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine A quiet policy change means the government is making fewer bets on long-term science.

Under Trump, the NIH is giving fewer grants to fewer scientists. The grants awarded are smaller and scientists have less time to spend them.

Projects in cancer, diabetes, aging, neurological disorder, and more are going unfunded.

“Make America Healthy Again.”

Time for universal basic income. Also, that is a great infographic!

Parsnips and leeks not so southern but incorporated from time we spent in the UK

Southern Sunday dinner!! Chicken and cornbread waffles, collard/mustard greens, carrots, parsnips and leeks, and black eyed peas (hiding at the bottom of the bowl)

Man detained by ICE found dead, hanging with hands and feet tied—attorney The Chinese national died in Pennsylvania in August, but his family's requests for answers from DHS have gone unmet.

Keep this story in the news.

"Man Detained by ICE Found Dead, Hanging With Hands and Feet Tied—Attorney"

www.newsweek.com/ice-detainee...

@xiaosigu.bsky.social @katenuss.bsky.social @mpwpaulus.bsky.social @coolscontrol.bsky.social @shotgunosine.bsky.social @avramholmes.bsky.social @jonroiser.bsky.social

@elliottwimmer.bsky.social @ashenhav.bsky.social @micahgallen.com @nathanieldaw.bsky.social @paulbsharp.bsky.social @stepalminteri.bsky.social @mkflugge.bsky.social @dralexharris.bsky.social @yaelniv.bsky.social @manonironside.bsky.social @tobywise.bsky.social @nilskolling.bsky.social

@thepsychologist.bsky.social @lukejchang.bsky.social @clairegillan.bsky.social @soerenkrach.bsky.social @docqhuys.bsky.social @johnclithero.bsky.social @diegopizzagalli.bsky.social @erika-forbes.bsky.social @iriskayichat.bsky.social @irisvilares.bsky.social @wouterkool.bsky.social

tagging some people who might want to follow #RewardSignals

@vanessabrown.bsky.social @akpoorni.bsky.social @mattmattoni.bsky.social @dvsmith.bsky.social @kimberlychiew.bsky.social @drjocutler.bsky.social @brainapps.bsky.social @dr-stan.bsky.social @iancballard.bsky.social

🧠💸 Launching the RewardSignals feed

RewardSignals is a custom feed collecting posts about reward processing and decision making.

To appear in the feed, tag your post with #RewardSignals.

You can find and pin the feed from the Feeds tab as “RewardSignals”.
#RewardSignals

Things that will get you kicked out of academia forever:
- taking maternity leave at the wrong time
- spending too much time with your kids
- reporting harassment
- not moving every 2-3 years
- taking a partner's job/preferences into account
- mouthing off before tenure

and it is totally down for me too

Very slow and sometimes will not load since the redesign, no matter which browser I use. Also, while we are on the topic, I really don't like the redesigned OSF site.

Childhood adversity, low positive affect and psychopathology: a meta-analytic structural equation modeling study - Nature Mental Health In this meta-analytic structural equation modeling study, Stoia et al. examined whether positive affect mediates the relationship between childhood adversity and psychopathology.

Childhood adversity, low positive affect and psychopathology: a meta-analytic structural equation modeling study www.nature.com/articles/s44...

Check out this cool new experimental study by Jonas Dora, et al on the effects of negative mood ☹️ and alcohol intoxication 🍺🍸on reinforcement learning!!

Any computational RL people have thoughts (or even better a link to a paper) about effect sizes in the context of RL parameters like learning rate?

I vaguely remember talking to someone about effect sizes possibly not being very meaningful…but a paper on the topic would be awesome!!

NEW: Epstein survivors release the most powerful PSA I have ever seen.

Make this go viral so every member of the House of Representatives sees it.

Any computational RL people have thoughts (or even better a link to a paper) about effect sizes in the context of RL parameters like learning rate?

I vaguely remember talking to someone about effect sizes possibly not being very meaningful…but a paper on the topic would be awesome!!

Suzanne Perkins, University of Michigan Research Center for Group Dynamics: “The promise of neuroscience is that you could target interventions that could really support what you feel is going wrong. If you know what the data shows is going wrong in the brain, you can start to improve that function and help them to thrive in school.”

Michigan helped reignite the career of cancer survivor Suzanne Perkins @20thofmay.bsky.social, whose research stems from the insight that education plays a key role in recovery for children at risk. Now she's crafting the future of learning: myumi.ch/9pWk3 #LifeChangingEducation #LookToMichigan