Dr. Elizabeth Crouch

Grateful and inspired by #CIRM funding and programing for the #ReMIND initiative. The future will be better for neuropsychiatric disease 🧠 🩺 🩸
@ucsfstemcell.bsky.social @bhadurilab.bsky.social @brainevodevo.bsky.social

🚨 My lab is hiring at all levels!

Interested in animal origins & evolutionary cell biology?

I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.

🔗: clarkelab.com/join/

Please repost!

Prenatal Acetaminophen Exposure Does Not Disrupt Human Fetal Brain Development in Cortical Organoid Models Acetaminophen (APAP) is the most widely used analgesic during pregnancy, yet epidemiological studies have reported conflicting associations between prenatal exposure and neurodevelopmental disorders (...

I freaking love that this team must have been like TIME TO PREPRINT

Prenatal Acetaminophen Exposure Does Not Disrupt Human Fetal Brain Development in Cortical Organoid Models

www.biorxiv.org/content/10.1...

Blue background with floating blue and pink cells. ImmunoX logo centered at the bottom. A navy box below reads: ‘Science is for everyone. Breaking Down Biology Blog.’

Schematic showing a molecular mechanism in the uterus of a mouse: To test the role of KDM6B (and gene regulation more generally) in determining labor timing, the researchers created mice that lacked the histone demethylase KDM6B in cells of the uterus called uterine fibroblasts. They found that, compared to control mice, those lacking KDM6B had a delayed drop in P4 and gave birth several days later. This suggested that without KDM6B, the uterus was unable to activate the gene program required to initiate labor at the proper time.

What if the uterus has a molecular clock to measure pregnancy length? Drs. Tara McIntyre and Adrian Erlebacher discuss their gene-regulation ‘timer’ discovery in mice with Alessandra Veinbachs. Click the links below to learn how this mechanism could reshape our understanding of gestational timing.

#Neuroscientists &
#neonatologists: check out The Brain Foundation
#Synchrony conference:
#neuroenergetics, #neuroinflammation & #vasculature. 🧠 🗣️ 👩‍🔬 🙋🏾‍♂️💭 by families, patients, clinicians & scientists 👏🏻highly productive! @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social @nicupodcast.bsky.social

#NICUfellows & #neonatology faculty: ✅ out Neonatal Early Career Exchange Program focused on networking for early career faculty. tinyurl.com/NECEprogram I hosted a ⭐ Dr. Lauren Frazer to discuss progress on #necrotizingenterocolitis. @ucsfchildrens.bsky.social @neotecan.bsky.social

Vascular remodeling and maturation in arteriovenous fistulas are improved by mesenchymal stem cells
www.science.org/doi/10.1126/...

#Breakingdownbio is back & 2.0 is upgraded w/ interviews! 🎙️this episode highlights 🤩 work on a uterine timer in pregnancy; Disruptions 🔜 #pretermbirth ⏰🤰❓A must read for #pediatrics #obgyn #reproductivehealth #immunology @ucsfstemcell.bsky.social @neotecan.bsky.social @ucsfchildrens.bsky.social

It’s an honor to work with Jaela and I’m looking forward to the training in mentorship. This PI job doesn’t come with an instruction manual!

The future of neonatal physician scientists is bright 🤩@benfens is the new @neotecan.bsky.social Research Chair with an awesome trajectory to date and some clever ideas on how to inspire creativity and community in our science for babies 👶🏻 👶🏽👶🏿

Stealth genomics startup focused on non-cancer diagnostic applications Senior Deep Learning Engineer • Ph.D. in relevant field with 3+ years practical experience in deep learning for biology • Demonstrated proficiency in building DL architectures using Pytorch or TensorFlow+Keras. • Substantial expertise in training lightweight deep learning models and tuning large foundation models. • Substantial expertise with developing efficient data loaders for large datasets and optimizing training workflows. • Deep expertise training and deploying models in Cloud-based compute environments and local hardware. • Sufficient knowledge of the genomics of gene regulation to ask the right questions for the specific information to be gained. • Expertise in developing models of gene regulation and sequence-to-function models is a plus. • Interactive team player in highly collaborative small setting. Experience collaborating and communicating with biologists. Interested candidates can send their CV to anshul @ kundaje . net

Job Alert: A stealth startup focused on non-cancer diagnostics is keen to hire a deep learning for genomics/bio engineer. I am an advisor for the startup & closely involved. Please see the job description below and get in touch if interested. Plz forward.

So proud of Kaylee who won a #GordonConference Travel Award! 🥇 🤩 Congrats to @brisapalikuqilab.bsky.social for a fantastic #GRS and Profs Karina Yaniv and Anne Eichmann for an outstanding #Angiogenesis conference @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social

Donate to Banerjee Family Birthday Donation Page Provide comfort and sanctuary to families of children with cancer and other life-threatening illnesses staying at Family House San Francisco. https://give.familyhouseinc.org/campaign/569799/donate

For their 1 year birthday, my patients Opu & Jojo are hosting #familyhouse fundraiser. Join us to celebrate #extremelypreterm patients & parents to ensure this resource persists for families @ucsfchildrens.bsky.social @neotecan.bsky.social ❤️👧🏾👶🏻👦🏽👩👨🏻 give.familyhouseinc.org/campaign/703...

A full circle ⭕️ moment interviewing @ameliecollins79 . Dr. Collins was my fellow during my #neonatology sub-I. Fascinating #hsc work (the mother cell of #immunology!) ✅it out and her 😍publication: pubmed.ncbi.nlm.nih.gov/38428422/ @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social

We have a VERY important episode, we need your help!🤝 It's not too late to influence your legislators.

PLEASE listen and ask yourself how you can help make positive change for families on Medicaid.🏥

@nicubatman says that your voice matters!🗣️

#nicu #medicaid #nicuparent #nicunurse
@nant @nann

David McCulley was kind enough to let me interview him about #grantwriting on the cusp of a major #NIH deadline. Nothing like a deadline 😅to curate a few 🔥tips

Bravo Patricia! And yes module scoring is 👏🏻🤩look forward to using it for #bloodbrainbarrier studies too

#Crouchlab and friends and family at the #UCSFCMFPM 10 year anniversary celebration 🍾 🎉thrilled to be a part of this #visionary group now w/#clinicaltrials for #inutero therapies. Let’s go for it, for children’s future health 👶🏻👧🏾🧒🏼 @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social

@neosatyan is a shining light in the neonatal community. Learn more about how he got his start in research on At the Bench, hosted by @mistygoodlab @davidh_mcculley and @elizabetscrouch.
#nicu #neotwitter #neosky #physicianscientist

We have a great new episode on @nicupodcast from our colleagues on the Global Neonatal Podcast! Neonatal care from Trinidad to Toronto! Be sure to take a listen!

#nicu #neonatal #nann #globalhealth

Ralph Kistler Internship | Hydrocephalus Association The Ralph Kistler Internship was established in 2021 and offers undergraduates hands-on experience in biology, neuroscience, public health, and non-profit operations.

Fantastic opportunity for undergradute students interested in 🧠#BrainHealth #hydrocephalus #research #sciencepolicy w/ the outstanding Hydrocephalus Association Patients, families, funders and researchers to #curehydrocephalus 🩺👩🏼‍⚕️💰🔬 www.hydroassoc.org/the-ralph-ki...

#291 - 🔬 Understanding Fetal Growth (ft. Dr. Paul Rozance) Hello Friends 👋In this episode of the Incubator, Dr. Paul Rozance discusses his research on fetal metabolism and growth regulation, emphasizing the role of insulin, glucagon, and placental function in...

Dr. Rozance studies how 👶🏻 grow in the womb. 🫄Bad prenatal growth can have serious long-term effects, including an ⬆️ risk of 🫀 disease & ⬆️blood pressure in adults. Why don’t some 👶🏻 grow well & how we can intervene to support their lifelong health? www.the-incubator.org/post/291-und...

If anyone is wondering what the impacts of cuts to NIH funding are, check out this really well-done website tracking them: scienceimpacts.org

It’s been gorgeous @ucsfstemcell.bsky.social and we took the opportunity to have a mtg on the roof! #laborganization goes more smoothly with abundant sun. ☀️💪🏻🧫🔬🥼

Congrats Carolyn!!! Well deserved.

The promise of cerebral organoids for neonatology : Current Opinion in Pediatrics . Human cell-derived cerebral organoid models are an appealing way to address some of these gaps. In this review, we will touch on previous work to model neonatal conditions in cerebral organoids, som...

#cerebralorganoids 🧠🧫hold much promise in #neonatology but have yet to deliver directly for our #patients 👶🏾👶🏻 We outline some high yield areas for future study (vasculature! Cortical circuits!) @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social ✅it out! journals.lww.com/co-pediatric...

The Game is On: Meet the UCSF Grad Slam Finalists! Get ready for UCSF Grad Slam! The Graduate Division’s popular annual research communications contest returns on April 2 as part of UCSF’s celebration of National Graduate Student Appreciation Week.

So proud of #Crouchlab MSTP KWP (Kaylee Wedderburn-Pugh)! Come listen to her amazing talk on #bloodbrainbarrier gene modules during development @ucsfstemcell.bsky.social 🧠💻🧬 graduate.ucsf.edu/news/game-me...

Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...

Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. www.biorxiv.org/content/10.1...

Stand up for Science rally March 7th noon-2pm Trenton, NJ State Capitol Plaza standupforscience2025.org

It’s happening, New Jersey! It’s time to rally for science!

Scientists Secure $10.3 Million CIRM Grant to Advance Stem-Cell Therapies for Neuropsychiatric Disorders A team of researchers from the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF and UCLA, along with the UC Santa Cruz Genomics Institute, has been awarded a $10.3 m...

Grateful for this funding and the opportunity to work with a phenomenal group of scientists to study a novel hypothesis with patient impact. 🧫🔬🥼👶🏻👧🏾👦🏽 @bhadurilab.bsky.social @zeigerlab.bsky.social
stemcell.ucsf.edu/news/scienti...