Parasite - The Journal

“Molecular analysis of DHFR and DHPS gene mutations in Plasmodium cynomolgi from humans and macaques in Southeast Asia"
The work investigates key mutations in the DHFR/DHPS genes that may contribute to drug resistance.🧪
doi.org/10.1051/para...

#Parasitology #DrugResistance

“Different patterns of Toxoplasma gondii infection – epidemiology in the general population, animal contact workers and blood donors in south-eastern China (2019–2023)”. The study reveals how IgG seroprevalence varies across population groups.
doi.org/10.1051/para...
#Toxoplasma #Epidemiology

Seroprevalence of Toxoplasma gondii (IgG) by gender and age in the general population, animal contact workers, and blood donors: (a and b, general population; c and d, animal contact workers; e and f, blood donors).

“𝗗𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝘁 𝗽𝗮𝘁𝘁𝗲𝗿𝗻𝘀 𝗼𝗳 𝗧. 𝗴𝗼𝗻𝗱𝗶𝗶 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻 𝗶𝗻 𝘁𝗵𝗲 𝗴𝗲𝗻𝗲𝗿𝗮𝗹 𝗽𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻, 𝗮𝗻𝗶𝗺𝗮𝗹-𝗰𝗼𝗻𝘁𝗮𝗰𝘁 𝘄𝗼𝗿𝗸𝗲𝗿𝘀 𝗮𝗻𝗱 𝗯𝗹𝗼𝗼𝗱 𝗱𝗼𝗻𝗼𝗿𝘀 𝗶𝗻 𝘀𝗼𝘂𝘁𝗵𝗲𝗮𝘀𝘁𝗲𝗿𝗻 𝗖𝗵𝗶𝗻𝗮 𝗯𝗲𝘁𝘄𝗲𝗲𝗻 𝟮𝟬𝟭𝟵 𝗮𝗻𝗱 𝟮𝟬𝟮𝟯.”🧪

This new paper analysed nearly 3 000 people and found clear differences by age, occupation and exposure to animals.

doi.org/10.1051/para...

𝗧𝗿𝘆𝗽𝗮𝗻𝗼𝘀𝗼𝗺𝗮 𝗲𝘃𝗮𝗻𝘀𝗶 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻 𝗶𝗻 𝗧𝘂𝗻𝗶𝘀𝗶𝗮: 𝗰𝘂𝗿𝗿𝗲𝗻𝘁 𝘀𝗶𝘁𝘂𝗮𝘁𝗶𝗼𝗻
This paper reviews recent data on this vector-borne parasite, its animal hosts, and the ongoing challenges in disease control across Tunisia.🧪
📖 doi.org/10.1051/para...

#Parasitology #Research

𝗧𝗿𝘆𝗽𝗮𝗻𝗼𝘀𝗼𝗺𝗮 𝗲𝘃𝗮𝗻𝘀𝗶 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻 𝗶𝗻 𝗧𝘂𝗻𝗶𝘀𝗶𝗮: 𝗰𝘂𝗿𝗿𝗲𝗻𝘁 𝘀𝗶𝘁𝘂𝗮𝘁𝗶𝗼𝗻
This paper reviews recent data on this vector-borne parasite, its animal hosts, and the ongoing challenges in disease control across Tunisia.🧪
📖 doi.org/10.1051/para...

#Parasitology #Research

Seroprevalence of Toxoplasma gondii (IgG) by gender and age in the general population, animal contact workers, and blood donors: (a and b, general population; c and d, animal contact workers; e and f, blood donors).

𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝘁𝗼𝗱𝗮𝘆: 🧪
Different patterns of Toxoplasma gondii infection epidemiology in the general population, animal contact workers, and blood donors in southeastern China between 2019 and 2023: a cross-sectional study
www.parasite-journal.org/articles/par...

Seroprevalence of Toxoplasma gondii (IgG) by gender and age in the general population, animal contact workers, and blood donors: (a and b, general population; c and d, animal contact workers; e and f, blood donors).

𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝘁𝗼𝗱𝗮𝘆: 🧪
Different patterns of Toxoplasma gondii infection epidemiology in the general population, animal contact workers, and blood donors in southeastern China between 2019 and 2023: a cross-sectional study
www.parasite-journal.org/articles/par...

Figure 2: Pleotelson widths of the assessed A. aquaticus individuals (n=535), according to sampling and infection status.

New paper in press:🧪
Potential effects of acanthocephalan and microsporidian parasites on the trophic status of the freshwater isopod Asellus aquaticus
Soon: www.parasite-journal.org

Geoplanids used in this study and their close environment. 1–2, Kontikia andersoni. 1, specimen MNHN JL467, unscaled; 2; origin of the specimen, below decaying wooden boards. 3–4, Australoplana sanguinea. 3, specimen MNHN JL472, unscaled; 4, origin of the specimen, below a concrete stone. Photographs by Stewart Rosell.

𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝘁𝗼𝗱𝗮𝘆:🧪
An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
doi.org/10.1051/para...

Geoplanids used in this study and their close environment. 1–2, Kontikia andersoni. 1, specimen MNHN JL467, unscaled; 2; origin of the specimen, below decaying wooden boards. 3–4, Australoplana sanguinea. 3, specimen MNHN JL472, unscaled; 4, origin of the specimen, below a concrete stone. Photographs by Stewart Rosell.

𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝘁𝗼𝗱𝗮𝘆:🧪
An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
doi.org/10.1051/para...

https://commons.wikimedia.org/wiki/File:Grey_crowned_crane_(Balearica_regulorum),_Ngorongoro_Conservation_Area.jpg public domain

Gametocytes of Haemoproteus balearicae (lineage hBAREGI210) from the blood of grey crowned crane Balearica regulorum: (a)–(i) – macrogametocytes, (j)–(o) – microgametocytes. Note: the slender form and markedly irregular gametocyte outlines, with numerous deep indentations providing various lobular-like appearances to the parasites (d, g, l–n). Long simple arrows – parasite nuclei; simple arrowheads - pigment granules; simple wide long arrows – indentations; short simple arrows – vacuoles. Giemsa-stained thin blood films. Scale bar = 10 μm.

𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝘁𝗼𝗱𝗮𝘆:
Diversity of haemosporidian parasites in cranes: description of Haemoproteus balearicae and its phylogenetic position within the H. antigonis clade 🧪
doi.org/10.1051/para...

Participants at ISOPS XI

New paper in press:
Recent advances in Phlebotomine sand fly research: a review based on studies presented at ISOPS XI 🧪
Soon... www.parasite-journal.org

@recherche.mnhn.fr

https://commons.wikimedia.org/wiki/File:Grey_crowned_crane_(Balearica_regulorum),_Ngorongoro_Conservation_Area.jpg public domain

Gametocytes of Haemoproteus balearicae (lineage hBAREGI210) from the blood of grey crowned crane Balearica regulorum: (a)–(i) – macrogametocytes, (j)–(o) – microgametocytes. Note: the slender form and markedly irregular gametocyte outlines, with numerous deep indentations providing various lobular-like appearances to the parasites (d, g, l–n). Long simple arrows – parasite nuclei; simple arrowheads - pigment granules; simple wide long arrows – indentations; short simple arrows – vacuoles. Giemsa-stained thin blood films. Scale bar = 10 μm.

𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝘁𝗼𝗱𝗮𝘆:
Diversity of haemosporidian parasites in cranes: description of Haemoproteus balearicae and its phylogenetic position within the H. antigonis clade 🧪
doi.org/10.1051/para...

This 2009 paper “Methods for parasitic protozoans detection in environmental samples” reached 15,000 downloads!
Still going strong after all these years — a sign that good methods never get old.🧪
doi.org/10.1051/para...

🧪 Trypanosoma evansi infection in Tunisia: current situation
Infection à Trypanosoma evansi en Tunisie : situation actuelle
مرض الدباب (الجُفَار) في تونس: الوضع الراهن
doi.org/10.1051/para...

🧪 Trypanosoma evansi infection in Tunisia: current situation
Infection à Trypanosoma evansi en Tunisie : situation actuelle
مرض الدباب (الجُفَار) في تونس: الوضع الراهن
doi.org/10.1051/para...

https://commons.wikimedia.org/wiki/File:%D0%9A%D1%80%D0%B5%D0%B2%D0%B5%D1%82%D0%BA%D0%B0_%22%D0%9E%D1%80%D0%B0%D0%BD%D0%B6%D0%B5%D0%B2%D0%B0%D1%8F_%D0%B2%D0%B8%D1%88%D0%BD%D1%8F%22.jpg

They began as aquarium pets. Now they swim free — and share parasites with wild crustaceans.
This new study uncovers a seasonal exchange of microsporidian infections between native and non-native hosts.
🧪🦀🦠 doi.org/10.1051/para...

https://commons.wikimedia.org/wiki/File:%D0%9A%D1%80%D0%B5%D0%B2%D0%B5%D1%82%D0%BA%D0%B0_%22%D0%9E%D1%80%D0%B0%D0%BD%D0%B6%D0%B5%D0%B2%D0%B0%D1%8F_%D0%B2%D0%B8%D1%88%D0%BD%D1%8F%22.jpg

They began as aquarium pets. Now they swim free — and share parasites with wild crustaceans.
This new study uncovers a seasonal exchange of microsporidian infections between native and non-native hosts.
🧪🦀🦠 doi.org/10.1051/para...

مرض الدباب (الجُفَار) في تونس: الوضع الراهن

🧪 doi.org/10.1051/para...

Dromedaries in Tataouine, South Tunisia around a drinking source. Note the presence of small “islands” of humidity and organic matter from animal faeces, representing a suitable microhabitat for the development of larvae of different blood-sucking flies.

New paper today: 🧪
Trypanosoma evansi infection in Tunisia: current situation
doi.org/10.1051/para...

مرض الدباب (الجُفَار) في تونس: الوضع الراهن

🧪 doi.org/10.1051/para...

#ReadingNow | New paper on vector-borne animal #trypanosomosis in #Tunisia

#YearOfCamelids

📑 Read paper: doi.org/10.1051/para...
👉 COMBAT project: doi.org/10.12688/ope...
👉 DIMCAT project: doi.org/10.1016/j.pt...
🗺️ Tsetse atlas: doi.org/10.4060/cd20...

@parasitejournal.bsky.social

Dromedaries in Tataouine, South Tunisia around a drinking source. Note the presence of small “islands” of humidity and organic matter from animal faeces, representing a suitable microhabitat for the development of larvae of different blood-sucking flies.

New paper today: 🧪
Trypanosoma evansi infection in Tunisia: current situation
doi.org/10.1051/para...

Example of IFAT-negative result obtained on a negative sample observed at 100× by using the IFAT kit FLUO Ehrlichia canis (Agrolabo S.p.A.).

Example of IFAT-positive result obtained on a positive sample observed at 100× by using the IFAT kit FLUO Ehrlichia canis (Agrolabo S.p.A.).

Canine ehrlichiosis, a tick-borne disease with zoonotic potential, is hard to diagnose. A new rapid ELISA test shows high accuracy in detecting Ehrlichia canis antibodies in dogs—helping vets catch infections earlier. 🧪
doi.org/10.1051/para...

Schematic representation of the first two generations (F0–F1) in the experimental transovarial transmission of B. ovis by R. bursa. The process led to the development of F2 larvae infected only with B. ovis, and the generation of virulent B. ovis (Alacakaya) stabilate.

🧪 Sheep babesiosis, caused by Babesia ovis, can pass from mother tick to offspring. Experiments show transmission persists for 4 tick generations—still causing severe disease. Key step for vaccine/pathogenesis research.
doi.org/10.1051/para...

(A) The homologous PcyDHFR protein structure of wild-type (light grey), human (pale cyan), and macaque (pale green) were aligned and shown in a ribbon structure. The mutations in protein were highlighted in the navy and red spheres for human and macaque samples, respectively. (B) Superimposition of four shared mutations between human and macaque P. cynomolgi. (C) The mutations in disordered protein residues from macaque isolates are shown as red ball and stick. Dashed lines represented a two-flexible loop structure, which is not well defined in the PvDHFR template crystal structure [15], and seven amino acid insertions in a sequence of PcyDHFR protein.

Plasmodium cynomolgi, a malaria parasite that infects both humans and macaques in SE Asia, shows gene changes but antifolate drugs may still work.
Monitoring is key to track emerging resistance.🧪
doi.org/10.1051/para...

Schematic representation of the first two generations (F0–F1) in the experimental transovarial transmission of B. ovis by R. bursa. The process led to the development of F2 larvae infected only with B. ovis, and the generation of virulent B. ovis (Alacakaya) stabilate.

🧪 Sheep babesiosis, caused by Babesia ovis, can pass from mother tick to offspring. Experiments show transmission persists for 4 tick generations—still causing severe disease. Key step for vaccine/pathogenesis research.
doi.org/10.1051/para...

Example of IFAT-negative result obtained on a negative sample observed at 100× by using the IFAT kit FLUO Ehrlichia canis (Agrolabo S.p.A.).

Example of IFAT-positive result obtained on a positive sample observed at 100× by using the IFAT kit FLUO Ehrlichia canis (Agrolabo S.p.A.).

Canine ehrlichiosis, a tick-borne disease with zoonotic potential, is hard to diagnose. A new rapid ELISA test shows high accuracy in detecting Ehrlichia canis antibodies in dogs—helping vets catch infections earlier. 🧪
doi.org/10.1051/para...

(A) The homologous PcyDHFR protein structure of wild-type (light grey), human (pale cyan), and macaque (pale green) were aligned and shown in a ribbon structure. The mutations in protein were highlighted in the navy and red spheres for human and macaque samples, respectively. (B) Superimposition of four shared mutations between human and macaque P. cynomolgi. (C) The mutations in disordered protein residues from macaque isolates are shown as red ball and stick. Dashed lines represented a two-flexible loop structure, which is not well defined in the PvDHFR template crystal structure [15], and seven amino acid insertions in a sequence of PcyDHFR protein.

Plasmodium cynomolgi, a malaria parasite that infects both humans and macaques in SE Asia, shows gene changes but antifolate drugs may still work.
Monitoring is key to track emerging resistance.🧪
doi.org/10.1051/para...