Silvia De Rubeis's Avatar

Silvia De Rubeis

@derubeislab.bsky.social

Neuroscientist & geneticist studying neurodev, autism, and DDX3X | PREP Director | Immigrant | 2x mom | #firstgen | #Humboldtian (she/her) Born and raised in ๐Ÿ‡ฎ๐Ÿ‡น, had fun in ๐Ÿ‡ง๐Ÿ‡ช, transplanted in ๐Ÿ‡บ๐Ÿ‡ธ Views my own https://labs.icahn.mssm.edu/derubeislab/

555 Followers  |  666 Following  |  138 Posts  |  Joined: 23.11.2024  |  1.7824

Latest posts by derubeislab.bsky.social on Bluesky

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NIH will reinstate 900 grants in response to court order Projects touching on sensitive topics such as DEI had been illegally terminated, judge found

New Science story about the beginnings of grant reinstatement.

www.science.org/content/arti...

27.06.2025 14:38 โ€” ๐Ÿ‘ 44    ๐Ÿ” 15    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
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Today, SfN joins communities across the nation in celebrating #Juneteenth โ€” a day that honors freedom, resilience, and progress.

We celebrate the remarkable contributions of Black neuroscientists whose research has expanded our understanding of the brain and improved lives worldwide.

#neurosky

19.06.2025 12:27 โ€” ๐Ÿ‘ 10    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Congratulations!

14.06.2025 00:56 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Congratulations!

14.06.2025 00:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
PA-25-422: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) PA-25-422. NI...

What? Some good news on a Friday?

Parent Fellowship Notices of Funding Opportunities are up!

F30, F31, F32, F33

grants.nih.gov/grants/guide...

13.06.2025 23:06 โ€” ๐Ÿ‘ 223    ๐Ÿ” 70    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
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Today is DDX3X Awareness Day!

12th June marks the fifth annual International DDX3X Day!

Share our expert-written guide, freely available online at bit.ly/3VlQ0D5

#DDX3X #RareChromo #GeneDisorder #ChromosomeX #AwarenessDay #Unique #FamilySupport

12.06.2025 11:22 โ€” ๐Ÿ‘ 1    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
PA-25-425: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Par... NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without N...

the reissued NOFO for theRuth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) is finally published! grants.nih.gov/grants/guide...

13.06.2025 18:23 โ€” ๐Ÿ‘ 5    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Padilla: If this is how DHS responds to a senator with a question you can only imagine what they're doing to farm workers, to cooks, to day laborers out in the Los Angeles community and throughout California.

12.06.2025 19:33 โ€” ๐Ÿ‘ 39390    ๐Ÿ” 13856    ๐Ÿ’ฌ 826    ๐Ÿ“Œ 782
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The Gutting of Americaโ€™s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant Some cuts have been starkly visible, but the countryโ€™s medical grant-making machinery has also radically transformed outside the public eye.

"Tanner, a chemist at the Univ. of Mississippi working to develop a novel approach for treating glioblastoma, was notified in April that the grant was terminated.

โ€œI would like to cure brain cancer,โ€ Dr. Tanner said. โ€œI think that's not particularly controversial.โ€

www.nytimes.com/interactive/...

08.06.2025 19:12 โ€” ๐Ÿ‘ 13751    ๐Ÿ” 5891    ๐Ÿ’ฌ 543    ๐Ÿ“Œ 322
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NEW STUDY from Adele Mossa, Lauren Dierdorff, Jeronimo Lukin, Silvia De Rubeis, et al. unveils sex-specific molecular signatures when Ddx3x is missing, impacting the neuronal proteome, protein synthesis machinery & nucleoli structure. Learn More @natcomms.nature.com ๐Ÿ‘‰ www.nature.com/articles/s41...

02.06.2025 00:00 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Careers - Centre for Population Genomics

Excited to be in Milan for #eshg2025! If youโ€™re interested in leading analysis of large, diverse cohorts with WGS and cellular genomic data in Australia, Iโ€™d be keen to chat - weโ€™re looking to fill a variety of senior comp bio roles: populationgenomics.org.au/careers/ #eshg25

24.05.2025 08:41 โ€” ๐Ÿ‘ 14    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Likewise, Marija! Definitely keeping in touch!

24.05.2025 21:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks Giannina for organizing this at @canacn.bsky.social. It was so much fun!

It was great seeing you and @arrudacarvalho.bsky.social again and meeting so many new friends!

@kundakoviclab.bsky.social @ivazovkic.bsky.social @walkerde.bsky.social @iordanova.bsky.social @deryasargin.bsky.social

24.05.2025 20:49 โ€” ๐Ÿ‘ 8    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Congrats!

24.05.2025 11:43 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Huge congratulations!

24.05.2025 11:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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To all those descending onto Toronto for the @canacn.bsky.social annual meeting, as program chair I hope you have an exciting meeting and enjoy our featured speakers @franklandlab.bsky.social
@yulonglilab.bsky.social @neurovoice.bsky.social @turrigiano.bsky.social and Kerry Ressler #CAN2025

20.05.2025 17:39 โ€” ๐Ÿ‘ 62    ๐Ÿ” 14    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Join us at CAN for genomic fun!

21.05.2025 21:37 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

OPT is the program that allows foreign students graduating with STEM degrees stay and work for up to three years. Because of the oversubscribed H-1B lottery, OPT is one of the main ways that foreign students manage to transition to jobs in the US.

Ending it would destroy a major STEM pipeline.

21.05.2025 21:43 โ€” ๐Ÿ‘ 949    ๐Ÿ” 449    ๐Ÿ’ฌ 65    ๐Ÿ“Œ 24
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If you are at @canacn.bsky.social , don't miss our symposium on Thurs 1:30 pm:

A genomics approach towards understanding sex differences in cognition, mental health, and neurodevelopment.

w @descalzi.bsky.social @ivazovkic.bsky.social @derubeislab.bsky.social @walkerde.bsky.social

See you there!

21.05.2025 16:26 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Screenshot of NIMH BRAINS funding opportunity. The expiration date is now before the next application due date.

Screenshot of NIMH BRAINS funding opportunity. The expiration date is now before the next application due date.

NIH moved up the expiration date for some funding opportunities, effectively *canceling* the next application date without removing it from the standard table. I can't even imagine how many people are still prepping these grants.

๐Ÿ‘€ List of impacted opportunities:
grants.nih.gov/grants/guide...

20.05.2025 13:48 โ€” ๐Ÿ‘ 88    ๐Ÿ” 80    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 15
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DDX3X-related neurodevelopmental disorder in males โ€“ presenting a new cohort of 19 males and a literature review - European Journal of Human Genetics European Journal of Human Genetics - DDX3X-related neurodevelopmental disorder in males โ€“ presenting a new cohort of 19 males and a literature review

Important new study by @lotsb.bsky.social and colleagues on #DDX3X variants in males ๐Ÿงฌ๐Ÿง 

Comment to the new insights provided by the study and future directions ๐Ÿ‘‡๐Ÿผ

urldefense.proofpoint.com/v2/url?u=htt...

@ddx3x-es.bsky.social @rarediseasesint.bsky.social

20.05.2025 20:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Trumpโ€™s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually Economists find public R&D drives U.S. productivity growth โ€” and pays for itself

New Forbes story about the economic consequences of science cuts.

www.forbes.com/sites/johndr...

Thoughtful and thorough analysis.

1/n

20.05.2025 20:28 โ€” ๐Ÿ‘ 122    ๐Ÿ” 89    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 8

New paper from our lab!

Happy to contribute to this collective effort, advancing our understanding of DDX3X and its role in #DDX3Xsyndrome

20.05.2025 13:54 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks so much!

18.05.2025 20:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks Mateusz ๐Ÿ˜‰

18.05.2025 19:26 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks so much Nael!

18.05.2025 18:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks for sharing!

18.05.2025 18:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks so much, Cedric!

18.05.2025 15:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X - Nature Communications Genetic mutations in the DDX3X gene are associated with a neurodevelopmental disorder primarily affecting females. Here authors show that Ddx3x mediates sexual dimorphisms during brain development at ...

Published now, in case you are interested โ˜บ๏ธ

www.nature.com/articles/s41...

18.05.2025 15:49 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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