Mary Fesenko

Mechanical forces stimulate Golgi export Human cells face a wide range of external mechanical stimuli that vary with cell type, state, and pathological conditions. The rapidly growing field of mechanobiology investigates how cells sense and ...

www.biorxiv.org/content/10.1...

Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells - Nature Chemistry The programmability of synthetic cells, comprising lipid vesicles that are capable of imitating the structure and function of living cells, facilitates their application as drug delivery devices. Now,...

We’ve developed the first-ever method to control nucleic acid activity and gene-expressing synthetic cells with a deeply tissue penetrating alternating magnetic field 🧬 🧪 🧲!!!

Published in *Nature Chemistry*

Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...

Fourth day of #SeptSRC rising with Jenna Perry showing that there are septin isoforms with transmembrane proteins.

I also loved that the plants in the surrounding garden were chosen for their connections to her story, with Everlasting Flower (powo.science.kew.org/taxon/urn:ls...) being a particularly poignant choice.

A metal statue of Henrietta Lacks, surrounded by shrubs with green and burgundy foliage and various flowers.

I serendipitously came across this beautiful Henrietta Lacks statue in Bristol yesterday, whose cells I put through so many manipulations during my MPhil and PhD. It’s mind-blowing to think of how many labs across the world are using her cells to make discoveries and she died having no idea of this.

I also second Mara on this tip + share her dislike of gel extractions!

If it’s any consolation, at one point during my PhD, I made an agarose gel with H2O instead of TAE/TBE + wondered why it was running weirdly for ~30 mins before realising. I had vowed never to do this again after undergrad when I wasted a lot of time before learning H2O was not the solvent to use.

Love this!

One of my favourite scenes from the BBC ‘Life Story’ documentary series!

This meeting could have been a walk in the sunshine

#newPI and time is running.

It has already been a month since I officially joined the University of Warwick as Assistant Professor. I am excited to announce and build the Fluorescence and Membrane Dynamics (FMD) Lab:

warwick.ac.uk/fac/sci/med/...

✅
Thank you, the earrings were a gift from a friend + former colleague @thilanibabuji.bsky.social 😊

A riddle for #GolgiDay: How many Golgis can you spot in this photo?

Hah I have actually considered this on a couple of occasions, but never been brave enough to do it!

On April 19, 1898, Camillo Golgi described what we now know as the #Golgi apparatus - a structure so pretty and unusual it took over fifty years for the scientific community to agree it wasn’t just an artefact.
April 19 is #GolgiDay! Mark your calendars to honour the best organelle.

GitHub - quantixed/p064p037: Code and data for manuscript p064p037 Code and data for manuscript p064p037. Contribute to quantixed/p064p037 development by creating an account on GitHub.

oops previous link was broken: github.com/quantixed/p0...

print("I look into the finance box just to check my status \nI look into the microscope, I see the Golgi Apparatus \nGolgi, oh, woe is me, you can't even see the sea \nGolgi, Golgi, Goh-oh-olgi, Golgi segmentation is complete \n - inspired by the song 'Golgi Apparatus' by Phish");

I put an ode to the Golgi into a Fiji macro I wrote and it made it into the Github repo associated with my paper 👌 Those who seek it shall find this Easter egg 🐣 on: github.com/quantixed/p0... (code snippet in the next post) @steveroyle.bsky.social

Do you want to understand better how LLMs work?
Do you want to use LLMs in applications in science or industry?
Join us for this two-day training in Leipzig! 🚀

Thanks! I’m a daily visitor on that site 😅👩‍💻

I’m currently looking for a post-doc in the UK, particularly to work on projects that employ in-vitro reconstitution and quantitative #microscopy approaches to study #cellbiology processes (esspecially #membranetraffic) + would be grateful for sign-posting towards openings! 🙏

And thank you @jcellsci.bsky.social for publishing an interview with me - I enjoyed reflecting on my work + journey in science so far! I’m looking forward to new chapters in my membrane trafficking adventures and hope to continue exploring how cell organelles shape-shift + communicate!

This story wouldn’t be here w/out @lizziecourthold.bsky.social, @moore-cell.bsky.social, Peyton Ewbank + other colleagues from @steveroyle.bsky.social’s lab who helped us along the way!

I had lots of fun fishing for vesicles during my PhD 🎣🔬 and I’m very happy to see the final version of this story out along with a wild cherry tree planted in the Forest of Biologists - a wonderful biodiversity-promoting initiative by @biologists.bsky.social!

An ancient woodland indicator, Wood anemone. Why? Because it mainly grows vegetatively and spreads slowly. Every year I take a photo of this same patch. Photos below from 2017 & 2025. @bsbibotany.bsky.social @lgspace.bsky.social @wtscotsocial.bsky.social

A photo of a blossoming saucer magnolia (Magnolia × soulangeana) tree against a blue sky, captured on a walk earlier today

It’s my favourite time of the year! 🌸
I’m loving seeing all the blossoming trees + flowers while out and about, esp. magnolias which remind me of my hometown of Kyiv.
Today, I also came across an unfamiliar flower species, which I learned was in the genus Anemonoides thanks to the iNaturalist app!

Really exited to be at #100biologists!
Come to my poster #120 NOW to hear about my PhD work with @steveroyle.bsky.social on characterising different flavours of intracellular nanovesicles!
We also have (moderately) exciting giveaway at my poster - check it out!

Future bandages could be armed with nanoflowers The tiny structures may help fight deadly bacteria like E. coli.

pretty and useful

copper phosphate and tannic acid possess anti-inflammatory and antibiotic properties

mixed in a saline solution, they self-assemble and grow into flower-like structures

the nanoflowers can be attached to small strips of electrospun nanofabric to make an antimicrobial bandage

I loved reading this! 🔬❤️

Thank you so much, Joe! 💪