Kyle MacQuarrie MD PhD's Avatar

Kyle MacQuarrie MD PhD

@kylemacquarrie.bsky.social

Pediatric oncologist and physician-scientist in Chicago, Asst Prof, big ol’ science nerd, πŸ³οΈβ€πŸŒˆ, views my own, etc etc

3,302 Followers  |  676 Following  |  516 Posts  |  Joined: 18.09.2023  |  2.0309

Latest posts by kylemacquarrie.bsky.social on Bluesky

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β€˜Seek Funding’ Step Added To Scientific Method PARISβ€”In an effort to modernize the principles and empirical procedures of examining phenomena and advancing humanity’s collective knowledge, the International Council for Science announced Thursday t...

β€˜Seek Funding’ Step Added To Scientific Method

05.08.2025 15:15 β€” πŸ‘ 1108    πŸ” 194    πŸ’¬ 12    πŸ“Œ 19
A corgi perched daintily on a pillow on a couch, so that no part of her is touching the couch directly.

A corgi perched daintily on a pillow on a couch, so that no part of her is touching the couch directly.

Like the princess and the pea, if the princess shed a LOT, and the pea was actually a perfectly comfortable couch.

04.08.2025 15:43 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a man in a suit and tie is sitting at a desk in an office and giving the middle finger . ALT: a man in a suit and tie is sitting at a desk in an office and giving the middle finger .
03.08.2025 01:27 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A peach and berry galette, fresh out of the the oven and sitting on some parchment paper.

A peach and berry galette, fresh out of the the oven and sitting on some parchment paper.

When life gives you fruit that’s starting to get a little old and soft, turn it into dessert. (Do this with new fruit too. Just make more dessert period.)

03.08.2025 01:23 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Who or what is β€˜Klarna’ and why are they willing to lend you money to buy this?

02.08.2025 22:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Pediatric hospitals don’t have a subset of specialists/services just for Medicaid patients

Cuts to Medicaid funding affect ACCESS & AVAILABILITY of programs and services for ALL CHILDREN

Cuts in NIH funding affect ALL RESEARCH, regardless of your child’s condition, ability to pay, insurance

30.07.2025 15:07 β€” πŸ‘ 85    πŸ” 36    πŸ’¬ 1    πŸ“Œ 0

If I’m reading this, does that make me Jack? Cause I’m not sure how I feel about that.

29.07.2025 14:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

few outcomes, except for 99% of FDA-approved drugs, 174 recipients of 104 Nobel Prizes, training ~30K MDs and ~10K PhDs per year to enter the workforce, and a 34% reduction in age-adjusted cancer deaths since 1990 -- the largest decrease in history

29.07.2025 03:26 β€” πŸ‘ 811    πŸ” 345    πŸ’¬ 14    πŸ“Œ 9

Missed the word β€˜knife’ at first and was deeply perplexed how you secure airways with a pen and a ribeye.

28.07.2025 01:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Next time somebody says "OMG calm down, they're not cutting cancer research!" Show them this graph.

25.07.2025 12:55 β€” πŸ‘ 108    πŸ” 47    πŸ’¬ 5    πŸ“Œ 1
Transforming the Approach to Cancer Epigenomic Studies – Pediatrics Nationwide

Very proud of our partner papers in @cp-cellreports.bsky.social and @cp-cellrepmethods.bsky.social from collaborative work in my lab and Benjamin Stanton's lab focused on fusion-positive #rhabdomyosarcoma. #TeamFishAndChIPs

25.07.2025 17:30 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

β€˜We would like to acknowledge our funding sources: a roadkill taxidermist and some chef influencer who only makes historically accurate pies.’

25.07.2025 13:38 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Clearly, that is the rival group that other members in your department can form after you form yours. Fans will love the drama!

24.07.2025 11:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a group of young men are dancing in front of a blue and white background with the letter n on it ALT: a group of young men are dancing in front of a blue and white background with the letter n on it

Through Autotune, all things are possible, so you just need to think about your new boy band’s branding. May I suggest N’Science?

24.07.2025 11:07 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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πŸ“’ Early-career researchers: you make up a majority of the scientific workforce! How can you leverage that to advocate for change?

1/ 🧡 Here are 6 tips for success πŸ‘‡
#ECRChat #PhDLife #AcademicChatter

Watch the webinar for more:
πŸ”— buff.ly/b2tmoL4

21.07.2025 14:56 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

New paper from the Center for Physical Genomics is out - building from the physics of chromatin packing to targeting chemotherapeutic resistance in vivo mice tumor models

Leveraging chromatin packing domains to target chemoevasion in vivo | PNAS www.pnas.org/doi/10.1073/...

22.07.2025 15:32 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

I find this entire scenario completely unsurprising tbh.

22.07.2025 02:49 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Nanoscale 3D DNA tracing in non-denatured cellsΒ resolves the Cohesin-dependent loop architecture of the genome in situ - Nature Communications A nanoscale 3D DNA tracing workflow visualizes Cohesin-dependent loops in single, structurally well-preserved cells. Computer simulations based on the tracing data give further insight into how Cohesi...

Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out!

www.nature.com/articles/s41...

Congratulations to Kai and Oyvind!!

21.07.2025 10:53 β€” πŸ‘ 55    πŸ” 23    πŸ’¬ 1    πŸ“Œ 0

Wouldn’t be my top choice, from the β€˜developmentally appropriate’ POV.

18.07.2025 22:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a close up of a woman wearing a wig and a necklace . ALT: a close up of a woman wearing a wig and a necklace .
18.07.2025 22:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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What season, spam email??

18.07.2025 12:43 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Graffiti at the end of an underpass in Heidelberg saying 'LAB!'.

Graffiti at the end of an underpass in Heidelberg saying 'LAB!'.

Some PIs will stop at nothing to motivate their lab members. πŸ§ͺ

12.07.2025 11:41 β€” πŸ‘ 118    πŸ” 17    πŸ’¬ 1    πŸ“Œ 3

It’s sort of looking like baby botox treatments, which is certainly…a choice.

16.07.2025 17:45 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Eats streets and beets link.  Website is here! https://www.sunydownstatepediatricgastroenterology.org/eats-streets-and-beets

Eats streets and beets link. Website is here! https://www.sunydownstatepediatricgastroenterology.org/eats-streets-and-beets

Are you a med student into Peds or nutrition, an early career RN investigator, early SLP/student, early RD/student or a Peds resident or fellow in the NYC area? Join us for a conference JUST for you, giving early career medical professionals an opportunity to share their work and highlight skills!

16.07.2025 17:39 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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a dog is jumping over a barrier in a room with a sign that says bw ALT: a dog is jumping over a barrier in a room with a sign that says bw

On your way to a meeting.

15.07.2025 13:44 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A bar graph showing the fraction of non-competitive renewal grants funded by month for Northwestern. Almost no grants were funded with budget start dates in From June 1 onwards.

A bar graph showing the fraction of non-competitive renewal grants funded by month for Northwestern. Almost no grants were funded with budget start dates in From June 1 onwards.

The situation is still dire for institutions such as Northwestern (shown here) where non-competitive renewals are still not being issued at an appreciable rate.

/fin for now

15.07.2025 12:33 β€” πŸ‘ 24    πŸ” 5    πŸ’¬ 1    πŸ“Œ 2
A meme about torts professors involving a heavily breathing cat and an elaborate news text box about a truly unfortunate chain of events.

A meme about torts professors involving a heavily breathing cat and an elaborate news text box about a truly unfortunate chain of events.

14.07.2025 20:07 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
A closeup of a seated corgi who has something white smeared across her nose and one eyebrow.

A closeup of a seated corgi who has something white smeared across her nose and one eyebrow.

Perks of a Sunday afternoon - getting to stuff your entire head into the yogurt container before it gets recycled.

13.07.2025 19:08 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Backyard raspberry bushes heavily laden with berries.

Backyard raspberry bushes heavily laden with berries.

A bowl filled with freshly picked raspberries being held in front of raspberry bushes.

A bowl filled with freshly picked raspberries being held in front of raspberry bushes.

Making progress towards my goal of my backup career being backyard berry farmer.

12.07.2025 15:59 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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UMass Chan Medical School faces shortfall of tens of millions of dollars in NIH funding The medical school's chancellor, Dr. Michael Collins, said nearly $42 million in grants expected by the institution's scientists for research and related expenses did not come through for the fiscal y...

I don’t know what the future will bring for my research program or my institution. But it isn’t good. None of this is good. We are being absolutely crushed, and I know we are not the only ones. www.wbur.org/news/2025/07...

12.07.2025 01:40 β€” πŸ‘ 97    πŸ” 37    πŸ’¬ 5    πŸ“Œ 3

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