UW Clinical Trials Institute

Clinical Trials Arena

Recent changes at the #FDA have changed the circumstances for #raredisease drug development, but this remains an area of opportunity for biotech companies. buff.ly/TBuTXiS via Clinical Trials Arena #clinicaltrials

The #FDA recently issued product-specific guidance for generic #drug development. buff.ly/M3aB8Wl #clinicaltrials

The damage done - Nature Medicine When clinical trials are suddenly halted by US funding cuts, there are repercussions for investigators and patients, and they do not stop at borders.

Federal #funding cuts have impacted at least 148 #clinicaltrials in the US, affecting over 138k patients. buff.ly/9dhoaJv via @nature.com #clinicalresearch

Cannabis Product Beats Placebo for Common Chronic Pain Phase III trial shows efficacy, but lacks comparison with other active treatments

Patients with chronic low back pain experienced clinically significant relief when taking an investigational #cannabis extract in a placebo-controlled clinical trial. buff.ly/VO4Pip5 via @medpagetoday.com #clinicaltrials #clinicalresearch

Vaccine given during pregnancy could protect babies from an invisible killer Shots target group B streptococcus, a little-known microbe that can cause stillbirths and life-threatening disease in infants

Fifty years ago, Dr. Carol Baker proposed vaccinating pregnant women to save babies from a deadly microbe. Now, the idea is finally nearing fruition. buff.ly/X76GcYa via @science.org #clinicaltrials #clinicalresearch

On this Research Administrators Day, we send a heartfelt THANKS to all of the administrative staff within the #clinicalresearch community @uwmadison.bsky.social and @uwhealth.bsky.social who work tirelessly to move medicine forward via #clinicaltrials innovation in #Wisconsin and beyond!

Rheumatoid arthritis kept her captive. This nerve stimulator set her free A new surgically implanted device the size of a lima bean can help control rheumatoid arthritis that isn't responding to drugs.

A patient with rheumatoid #arthritis is improving thanks to a surgically implanted device that was recently approved by the #FDA. buff.ly/Ex7PTN8 via @npr.org #clinicaltrials

Blockbuster Cancer Drug Can Now Be Administered More Easily Approval of subcutaneous pembrolizumab covers existing solid-tumor indications

The #FDA recently approved the administration of a major #cancer drug by injection. It was previously only available via IV. buff.ly/XeqGI7Z via @medpagetoday.bsky.social #clinicaltrials

cancer recurrence in patients whose colorectal cancer is driven by a genetic mutation #https://buff.ly/UUcO9F3

Daily Aspirin Cuts Colon Cancer Recurrence Risk By Half THURSDAY, Sept. 18, 2025 (HealthDay News) — Aspirin can cut by more than half the risk that colon cancer will come back following initial treatment, a new clini

Researchers found that daily aspirin may reduce the risk of #cancer recurrence by 55% in patients whose colorectal cancer is driven by a genetic mutation. buff.ly/UUcO9F3via @healthday.bluesky.social #clinicaltrials #clinicalresearch

UW–Madison researchers test psilocybin, the compound in “magic mushrooms,” as new tool in mental health care In one trial focused on methamphetamine use, participants saw dramatic reductions in use, with some remaining abstinent months later.

@uwmadison.bsky.social researchers are leading national studies on psilocybin, to determine whether the psychedelic compound could offer lasting relief for #mentalhealth and substance use disorders. buff.ly/7lyzrZj via @wmtvnews.com #psychedelics #clinicaltrials

Using biobanks to boost research: a how-to guide From large national databases to bespoke sample collections, biobanks offer a wealth of avenues for scientific enquiry.

Researchers studying human health often find themselves in need of more, and more-diverse, samples, leading them to biobanks for assistance. buff.ly/1RKCh0j via @nature.com #clinicaltrials #clinicalresearch

Reimagining Clinical Trials for Remote Populations | Applied Clinical Trials Online How decentralized clinical trial designs and smart data integration are transforming the patient experience.

The development of digital tools and wearable sensors, along with real-time data collection and a growing commitment to patient centricity, has propelled a shift toward decentralized #clinicaltrials. buff.ly/FhlaYi6 via Applied Clinical Trials #clinicalresearch

Another New Hampshire man gets a pig kidney as transplant trials are poised to start A self-described science nerd is the latest American to get an experimental pig kidney transplant. Doctors at Massachusetts General Hospital announced Monday that Bill Stewart of Dover, New…

#Clinicaltrials are poised to start as another human receives an experimental pig kidney #transplant. buff.ly/TPjQbDJ via @apnews.com

'One and done' dose of LSD keeps anxiety at bay People with generalized anxiety disorder improved significantly after they got a single dose of LSD powerful enough to induce a psychedelic trip.

A new study finds that a single dose of LSD may ease anxiety and depression for months. buff.ly/RS0jP9w via @npr.org #mentalhealth #psychedelics #clinicaltrials

FDA greenlights trial for pig kidney transplant - Becker's Hospital Review | Healthcare News & Analysis Mass General Brigham, based in Somerville, Mass., and eGenesis have received FDA approval for a clinical trial testing genetically engineered pig kidneys.  The trial will evaluate the safety,…

The #FDA recently approved a clinical trial that tests the safety, efficacy, and tolerability of genetically engineered pig kidneys for #transplant in humans. buff.ly/oKJuMUJ via Becker's Hospital Review #clinicaltrials

Once a Death Sentence, This Heart Condition Is Finally Treatable A quiet revolution in care is helping patients with cardiac amyloidosis, a form of heart failure that long stumped doctors.

The power of #clinicaltrials: Until recently, cardiac amyloidosis was a death sentence, but the advent of new medications has made this disease increasingly manageable. buff.ly/cdOWNKj via @nytimes.com #clinicalresearch

Solving medical mysteries: Groundbreaking research underway at UW-Madison Lab The cause of rare diseases is often shrouded in mystery.

@uwmadison.bsky.social researchers are vigorously working toward identifying causes and eventual treatments for those living with rare and undiagnosed diseases. buff.ly/Wuk8SaE via @startribune.com #raredisease #clinicaltrials

Doctor, professional photographer calls for more research on art and neurological health Dr. Ahmed Obeidat is an artist himself — a poet and a professional photographer. He says his art allows him to reflect on the similarities within structures of nature and neurology.

A neurologist says practicing #art clinically benefits #MS patients. buff.ly/QeLPrSd via Wisconsin Public Radio #clinicaltrials

Clinical Trials Arena

Recent research shows that the shingles #vaccine may reduce the risk of #dementia. buff.ly/pOSzIf5 via Clinical Trials Arena #clinicaltrials

Jon Audhya on impacts of federal funding cuts at UW-Madison Editor's note: PBS Wisconsin is a service of the University of Wisconsin-Madison and the Wisconsin Educational Communications Board.

@uwmadison.bsky.social's Dr. Jon Audhya considers how deep cuts to federal research #funding are affecting scientific work and training of students. buff.ly/AhamTq3 via @pbswisconsin.bsky.social #Wisconsin #clinicalresearch

A truly inspiring story about how a patient's participation in a clinical trial @uwmadison.bsky.social has helped him thrive, despite a spinal muscular atrophy (#SMA) diagnosis at birth. www.uwhealth.org/news/spinal-... via @uwhealth.bsky.social #raredisease #clinicaltrials