Maximising imaging volumes of expanded tissues for inverted fluorescence microscopy https://www.biorxiv.org/content/10.1101/2025.09.12.675899v1
13.09.2025 03:48 — 👍 6 🔁 4 💬 0 📌 1
I think expansion only "clears" the sample because it dilutes it. E.g. 4x expansion is 4x4x4=64 times dilution. I'm guessing the proteases/heat used in expansion don't contribute much, if at all, to clearing.
06.03.2025 22:32 — 👍 0 🔁 0 💬 1 📌 0
Expansion microscopy is sort of like a clearing technique. Also ideal for lightsheets with water dipping objectives as the expanded sample ends up with a similar refractive index to water.
06.03.2025 20:57 — 👍 5 🔁 0 💬 2 📌 0
A fun and creative way to learn about someone's work
17.02.2025 19:21 — 👍 2 🔁 0 💬 0 📌 0
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13.12.2024 11:50 — 👍 27 🔁 21 💬 2 📌 3
Only very distantly, I guess!
21.11.2024 07:50 — 👍 0 🔁 0 💬 0 📌 0
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