Pedro Santamaria's Avatar

Pedro Santamaria

@p-santamaria.bsky.social

Retired researcher in Developmental Genetics, Evo-Devo. Drosophila. Polycomb Group. (PRC genes. "polyhomeotic" & etc.), Nuclear transplantation in the egg. Cell mosaics and chimeras. Epigenesis in Drosophila. CSIC --> CNRS. Hobby: mosaics.

154 Followers  |  252 Following  |  1,412 Posts  |  Joined: 25.01.2025
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Posts by Pedro Santamaria (@p-santamaria.bsky.social)

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Members of Congress Request Investigation into Alleged Reports that Military Leaders Claim War in Iran Part of Biblical End-Times Prophecies | U.S. Congressman Jared Huffman The Official U.S. Congressional website of Congressman Jared Huffman

Once more another Religious War ! We must ensure that military operations are guided by facts and the law, not end-times prophecy and religious beliefs. Pete Hegseth and civilian officials have publicly framed Middle East policy in explicitly religious terms.

huffman.house.gov/media-center...

10.03.2026 07:15 — 👍 0    🔁 0    💬 0    📌 0

No reason to be smug ! Decartes was wrong in lots of things.

09.03.2026 07:37 — 👍 0    🔁 0    💬 0    📌 0
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A Brain-Invading Worm Spread By Rats and Snails Has Reached California Researchers have found evidence the rat lungworm is now endemic in southern California

Robert Francis Kennedy Jr, was in California !

gizmodo.com/a-brain-inva...

08.03.2026 07:40 — 👍 0    🔁 0    💬 0    📌 0
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Bal de Pourim 2026. « Pourim judéo-arabe ! » Événement : DJ set de Sharouh et lecture du récit d'Esther par Arielle WilhelmVenez déguisés, venez danser !

Is for today, 08/03/2026, (dating with Esther). In Paris.

www.mahj.org/fr/programme...

08.03.2026 07:35 — 👍 0    🔁 0    💬 0    📌 0
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Decoding Your Connections: Introducing Advanced DNA Comparison Explore your family history with 23andMe’s Advanced DNA Comparison. Visualize shared DNA segments and map your genealogy with precision.

Still, again, an idea for people who like "Deepen Roots".

blog.23andme.com/articles/rei...

08.03.2026 07:27 — 👍 0    🔁 0    💬 0    📌 0
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Introducing DNA Relatives Clustering: A New Way to Map Genetic Connections at 23andMe Discover your roots with DNA Relatives Clustering. Automatically visualize genetic connections and map complex family branches.

They (23&Me) are trying to sell a (good) idea. But (common) people is (might not be, probably), (I fear) ready to understand "Clustering" (or pay for it).

blog.23andme.com/articles/int...

08.03.2026 07:16 — 👍 0    🔁 0    💬 0    📌 0
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Polycomb repression works without Siesta, the Drosophila ortholog of mammalian PCGF3 - PubMed Polycomb group proteins mediate epigenetic repression via multisubunit complexes, including canonical Polycomb Repressive Complex 1 (PRC1), which monoubiquitylates histone H2A and binds histone H3 trimethylated at lysine-27 (H3K27me3). The RING1 subunit of PRC1, critical for H2A ubiquitylation, form …

To read !

pubmed.ncbi.nlm.nih.gov/41790891/

07.03.2026 08:26 — 👍 1    🔁 0    💬 0    📌 0
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The Moral Reasoning Gap in American Christianity How education, church attendance, and tradition shape whether Christians rely on faith or science

The proof that "Believing is Misleading". (Evangelicals, the worst).

www.graphsaboutreligion.com/p/the-moral-...

07.03.2026 08:19 — 👍 0    🔁 0    💬 0    📌 0
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Una IA entrenada con 128 000 especies permite diseñar genomas o predecir enfermedades El modelo Evo 2, publicado esta semana en la revista Nature, es capaz de leer y escribir el código genético de todos los dominios de la vida con una precisión superior al 90 % en la detección de mutaciones patogénicas. Es el último de un grupo de modelos que han hecho avanzar el campo de la genética generativa.

I fear that AI lacks the need (Human) imagination to predict Regulation of Gene Expression or Epigenesis.
And the role of the PRC1 and PRC2 viriations on evolutive mudulation of gene expression.

www.agenciasinc.es/Noticias/Una...

07.03.2026 07:28 — 👍 0    🔁 0    💬 0    📌 0
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¿Dónde están las mujeres (científicas) en las noticias? A pesar de que las mujeres sostienen casi el 40 % de la investigación en España, su voz sigue infrarrepresentada en el espacio público. Esta brecha de visibilidad no solo distorsiona la percepción del talento investigador, sino que impone un techo de cristal simbólico en el imaginario infantil, alejando a las niñas de la ciencia antes incluso de que decidan su vocación.

Tomorrow 08 / 03 / 2026. Make ♀ ♀ = ♂ ♂ (great again ? 😉😉 ).
¿Dónde están las mujeres (científicas) en las noticias?: www.agenciasinc.es/Reportajes/D...

07.03.2026 07:06 — 👍 0    🔁 0    💬 0    📌 0

La prière est digne des peuples comme l'Iran !

06.03.2026 17:03 — 👍 0    🔁 0    💬 0    📌 0
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“Que Dieu bénisse l’Amérique”: prière collective en temps de guerre à la Maison-Blanche En pleine guerre contre l’Iran, un groupe de pasteurs évangéliques a été reçu ce jeudi à la Maison-Blanche le temps d’une prière collective en compagnie de Donald Trump, <a href="https://www.lefigaro....

Comment est ce possible ?
C'est puérile, naïf et surtout Ridicule !!
www.7sur7.be/monde/que-di...

06.03.2026 17:01 — 👍 0    🔁 0    💬 1    📌 0
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Promoter competition and Polycomb response elements govern transvection efficiency between co-regulated engrailed and invected genes in Drosophila Transvection (or trans-activation) is a process whereby an enhancer on one chromosome activates the promoter of a gene on a paired homologous chromosome. M

Read this !

academic.oup.com/genetics/art...

06.03.2026 08:56 — 👍 0    🔁 0    💬 0    📌 0
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In #GENETICS, Cheng et al. show how promoter competition between engrailed and invected genes and local polycomb response elements regulate transvection efficiency and trans-activation in #Drosophila. buff.ly/dKr62KI

05.03.2026 19:05 — 👍 2    🔁 1    💬 0    📌 0
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Could Life on Earth Have Descended From Microbes That Traveled From Mars Long Ago? Scientists demonstrated that an Earthly extremophile might withstand being ejected from the Red Planet on debris spewed into space due to an asteroid strike

- May (Heaven willing !) this find kill the archaic, assumed, or suposed, need of an (preposterous) "Creator" !

www.smithsonianmag.com/smart-news/c...

06.03.2026 08:31 — 👍 0    🔁 0    💬 0    📌 0
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China's New 5-Year Plan: More AI, Less US Maybe it really is the dawning of the Chinese Century.

- From a Historic Viewpoint or Perspective, no country keeps the leader of the World for more than one or two centurys.
- The trend of the barycenter "Dawn of Power" slip, or move with the "Sunset": Westward.
- So, even if you don't like... get (or make your F1) Ready !

gizmodo.com/chinas-new-5...

06.03.2026 08:12 — 👍 0    🔁 0    💬 0    📌 0
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Identical twins on trial: can DNA testing tell them apart? In a French criminal trial, conventional DNA analysis couldn’t distinguish between twin brothers, but emerging scientific methods could help in such cases.

- "Conventional DNA testing of Identical Twins can't discriminate. But eventually a process called methylation, which can change how genes work, can. These ‘epigenetic’ changes can be caused by factors including a person’s behaviours".

www.nature.com/articles/d41...

06.03.2026 07:34 — 👍 0    🔁 0    💬 0    📌 0
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Many heat-stressed tropical insects are reaching their limits Vast study in Peru and Kenya confirms limited defenses against rising temperatures, redoubling climate concerns

- "Flies were the most sensitive".

www.science.org/content/arti...

06.03.2026 06:51 — 👍 0    🔁 0    💬 0    📌 0

Vinegar fly = Drosophila melanogaster.

05.03.2026 09:08 — 👍 0    🔁 0    💬 0    📌 0
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Just three molecules can launch gene-silencing condensates in stem cells: A groundbreaking study published in _Molecular Cell_ reveals that just three molecules of the Polycomb protein CBX2 are sufficient to initiate the formation of gene-silencing condensates in mous… https://ranked.news/268920?u=b

05.03.2026 00:05 — 👍 1    🔁 1    💬 0    📌 0
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4/ We propose that H3K27me3 mimicry has repeatedly emerged during evolution as a mechanism to antagonise PRC2 and restrict the spread of Polycomb domains.

04.03.2026 23:58 — 👍 3    🔁 1    💬 1    📌 0
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3/ In mice, we show that mutations that disrupt H3K27me3 mimicry delay the activation of Hox genes and cause homeotic transformations characteristic of Polycomb gain of function.

04.03.2026 23:58 — 👍 2    🔁 1    💬 1    📌 0
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Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains Some proteins mimic the repressive mark H3K27me3, but the physiological relevance of this phenomenon was unclear. Agius et al. show that the PRC2 subunits JARID2 and PALI1 mimic H3K27me3 to antagonize...

1/ 🧵 In our new paper, we show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2. www.cell.com/molecular-ce...

04.03.2026 23:58 — 👍 55    🔁 23    💬 1    📌 2
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Así funcionan los eclipses solares: ¿por qué, cómo, cuándo, dónde? En 1959 pudo verse el último eclipse total de sol hasta hoy en España, solo en las islas Canarias. En la Península, el último total acaeció hace más de un siglo, en 1912. Esta escasez histórica se rompe ahora con una racha excepcional, dos totales y otro anular en solo tres años. ¿Cómo se explican estos fenómenos?

🌘 Tras más de un siglo sin un eclipse total visible desde la Península, España encadena una racha extraordinaria: tres espectáculos solares en solo tres años, entre totales y anular. Una coincidencia astronómica tan rara como fascinante.

Por Javier Yanes

www.agenciasinc.es/Reportajes/A...

02.03.2026 10:32 — 👍 5    🔁 2    💬 0    📌 0
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Désinformation : Il est temps de renvoyer Orwell dans la fiction | Le Canard enchaîné Les attaques répétées contre la science n'ont jamais été aussi fortes et propulsent le monde dans de nouveaux obscurantismes. La sortie simultanée d'un documentaire……

Sur @lecanardenchaine.fr Il est temps de renvoyer Orwell dans la fiction

www.lecanardenchaine.fr/culture-idee...

02.03.2026 10:37 — 👍 0    🔁 0    💬 0    📌 0
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IA : une start-up de San Francisco veut bâtir un « scientifique artificiel » pour « guérir toutes les maladies » Edison Scientific a conçu un agent IA capable de réaliser en quelques heures un objectif de recherche qui aurait demandé six mois de travail à des doctorants en biologie.

- Building an "Arificial Scientist" ??
- He is wrong evidently !

www.lemonde.fr/economie/art...

02.03.2026 08:29 — 👍 0    🔁 0    💬 0    📌 0
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Trump is feeling his way along the war on Iran The president has made numerous, often confusing media appearances since the start of the offensive on February 28, while only a third of Americans believe that the US-Israeli airstrikes are justified...

- The (often confused) Cow-boy mix-up the Far-West with the Middle-Est !
- (Any more presbyterian, but christian non-denominational. Trying to blow down or make it fall a Theocracy) - (😄)...
( "in God they trust" ! )

www.lemonde.fr/en/internati...

02.03.2026 08:10 — 👍 0    🔁 0    💬 0    📌 0

Dans une Théocratie... on ne peut pas tuer Dieu.

01.03.2026 18:25 — 👍 0    🔁 0    💬 0    📌 0

Pour Allende, ou d'autres, on le faisait en "catimini" (sans l'avouer). Mais Dumb'o est un Plouc !

01.03.2026 08:50 — 👍 0    🔁 0    💬 0    📌 0

And even "Not rare"... also.

01.03.2026 08:36 — 👍 1    🔁 0    💬 1    📌 0