Toby Baril

Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen - Nature Communications In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...

TEs aren’t just genomic parasites, they’re also engines of genomic novelty.

Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.

With @danielcroll.bsky.social & @guidopuccetti.bsky.social

🧬 www.nature.com/articles/s41...

#TEworldwide

The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons Background. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual gene...

Excited to share our new preprint on BioRxiv!
A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1...
1/5

A comparative analysis of transposable element diversity and evolution across 75 bee genomes - BMC Genomics Transposable elements (TEs) are repetitive DNA sequences that can alter their position and abundance within genomes. While TEs are known to have various impacts on genome structure and function, our u...

#TEsky A comparative analysis of transposable element diversity and evolution across 75 bee genomes doi.org/10.1186/s128...

High‐Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon‐Driven Structural Dynamics in Fungi Evolution Long terminal repeat retrotransposons (LTR-RTs) are recognised as a significant evolutionary force capable of shaping the structure and function of the genomes in eukaryotes, including animals, plant...

High-Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon-Driven Structural Dynamics in Fungi Evolution

doi.org/10.1111/1755...

#TEworldwide #TEsky

Awesome talk @orpsf.bsky.social! Excited to see what comes next!

#TEworldwide #TESky

Thrilled to be at @embl.org in Heidelberg for #EMBOMobileGenome workshop — an inspiring gathering of the transposable element community!
Find me at poster #54, exploring DNA methylation of L1 and Alu in individuals with varying benzene exposure.

#TEworldwide #TEsky

#TEsky Evolution of Mutator transposons in the genomes of worms doi.org/10.1016/j.ge...

☕ Coffee break time at #EMBOMobileGenome!

Inspiring talks, lively discussions, and plenty of caffeine to keep the ideas flowing. The sun’s out, the conversations are buzzing, and tonight we’ll keep the networking going with rooftop lounge drinks 🍂🍁

Looking forward to an exciting week ahead! 🧬

At @embo.org #EMBOMobileGenome and want to connect with other TE researchers and follow the latest goings on?

Use #TEworldwide and #TEsky in your posts to be featured in the TEworldwide feed, which you can also find here:

bsky.app/profile/did:...

#TEworldwide #TEsky

Time to kick off #EMBOMobileGenome for 2025! A great selection of speakers and posters on the agenda!
#TEWorldwide #TESky

Co-opted transposons help perpetuate conserved higher-order chromosomal structures Transposable elements (TEs) make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for architectural proteins, such as CTCF, RAD21, and SMC3, that are involved in ...

Transposable elements (TEs) do more than regulate genes; they help shape and preserve 3D genome structure across species.

Uncover the science behind it: pmc.ncbi.nlm.nih.gov/articles/PMC...

@tobybarilbio.bsky.social and I are very excited to release MycoMobilome! A very extensive effort to discover, QC and annotate TEs across the fungal kingdom.

👉 Ready-to-use for your own genome with a simple tutorial!
👉 Metadata about TEs discovered in your genome!
👉 Contribute and get recognition!

Please feel free to share with any fungal biologists, or those interested in annotating TEs in fungal genomes, and we look forward to expanding #MycoMobilome with community contributions!

@danielcroll.bsky.social
#TEsky
#TEworldwide
#Databases
#Genomics
#Bioinformatics
#Research
#Fungi

4/ Finally, we provide guidelines for community contributions, and encourage researchers to deposit new or curated sequences, which will be incorporated into future MycoMobilome releases. This can be done through the community on Zenodo: zenodo.org/communities/...

3/ We also provide metadata to enable evaluation of TEs of interest and to determine whether further curation work is required on a case-by-case basis

2/ The initial database contains 276,641 consensus sequences after filtering to remove host genes and low-quality consensi. We provide a consistent naming convention to indicate classification confidence, including potential conflicting ORF functions

1/ Ever needed to annotate TEs in a fungal genome, but didn't know where to start?

We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes!

www.biorxiv.org/content/10.1...

#TEsky #TEworldwide

The phenotypic variation of widefins medaka is due to the insertion of a giant transposon containing a viral genome within hoxca cluster Abstract. Phenotypic variation in species arises from genetic differences and environmental influences on gene expression. Differences in epigenetic modifi

"(...) an extremely large transposon, Teratorn, containing a herpesvirus genome, was inserted into the hoxc12a 3' UTR. This insertion decreased hoxc12a expression & (...) also affected neighboring hox genes, resulting in variations in fin size and the presence or absence of dorsal fins."

#TEsky RNA triple helix assembled by the poly(A) tail enhances retrotransposon mobilization by preventing RNA deadenylation doi.org/10.1073/pnas...

Technician III - Department of Microbiology Position Summary This position will be in the lab of Dr. Joseph E. Peters in the Department of Microbiology. Research in the Peters’ lab broadly involves deciphering mechanisms in genome stability and...

The Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition. cornell.wd1.myworkdayjobs.com/CornellCaree...

Thrilled to share what we learned from re-annotating the mobilome of the brown algae model [Ectocarpus] 🌊🌿🏖️

genomebiology.biomedcentral.com/articles/10....

A wonderful collaboration with @ericadinatale.bsky.social, @cssmartinho.bsky.social, @rorycraig.bsky.social, and Susana Coelho! 🎉

Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky

💥 New preprint! 💥
We show that transposons are directly linked to a cell-type and region specific inflammatory state in Parkinson’s Disease 🧠🦠

What a team @jakobssonasap.bsky.social! Funded by @asapresearch.parkinsonsroadmap.org

#Parkinsons #Neuroinflammation #TEworldwide #singlecell #TEs

How Did Evolution Halve Genome Size During an Oceanic Island Colonization? Abstract. Red devil spiders of the genus Dysdera colonized the Canary Islands and underwent an extraordinary diversification. Notably, their genomes are ne

Red devil spiders from the Canary Islands have a genome half the size of mainland counterparts - Pisarenco, @jrozasub.bsky.social et al. show how purifying selection against slightly deleterious DNA and TE insertions is the primary mechanism.

🔗 doi.org/10.1093/molbev/msaf206

#evobio #molbio #TEsky

BARBARA MCCLINTOCK - NobelPrize.org Throughout her career, medicine laureate Barbara McClintock studied the cytogenetics of maize, making discoveries so far beyond the understanding of the time that other scientists essentially ignored ...

Barbara McClintock - Nobel Prize in 1983!

www.nobelprize.org/stories/wome...

#TEsky #TEworldwide

Chromosomal Inversions Mediated by Tandem Insertions of Transposable Elements Abstract. Chromosomal inversions play a crucial role in evolution by influencing phenotypes through the linkage of coadapted alleles. While inversions have

@robinaraya.bsky.social @naturalselection.bsky.social @kjetillsj.bsky.social et al. investigate TEs in four large inversions in Atlantic cod - TEs accumulate in breakpoints, suggesting they drive inversions through ectopic recombination.

🔗 doi.org/10.1093/gbe/evaf131

#genome #evolution #TEsky

#TEsky #TEworldwide