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Mark Howarth Lab

@howarthsci.bsky.social

Mark Howarth research group at University of Cambridge Department of Pharmacology: Innovating Protein Technologies for Therapeutics and Vaccine Design. www.howarthgroup.org

111 Followers  |  68 Following  |  18 Posts  |  Joined: 28.11.2024
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Posts by Mark Howarth Lab (@howarthsci.bsky.social)

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A double helix twist in HIV vaccine design DNA origami scaffolds displaying HIV antigens stimulate focused antibody responses in mice

Our perspective with Oliver Bannard on DNA origami for vaccination is out: www.science.org/doi/10.1126/...

06.02.2026 15:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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a poster that says do n't panic in red letters ALT: a poster that says do n't panic in red letters

Our alum Douglas Adams: "I love deadlines. I like the whooshing sound they make as they fly by". Well, we had a deadline and after whooshing/gnashing, now we’ve another for you- 23 Feb. Many exciting submissions so far to "Integrating chem/eng/biol for next gen of vaccines" and still time for more

06.02.2026 15:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Two weeks left to register and submit abstracts for our symposium in Cambridge "Integrating chemistry, engineering and biology to create the next generation of vaccines"
@rscchembio.rsc.org @rsc-ppsg.bsky.social @cambridgephysics.bsky.social @eng.cam.ac.uk @rscbiomaterchem.bsky.social #vaccines

14.01.2026 10:45 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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mRNA delivery of genetically encoded mosaic-8 pan-sarbecovirus RBD vaccines Global health remains threatened by spillovers of zoonotic SARS-like betacoronaviruses (sarbecoviruses) that could be mitigated by a pan-sarbecovirus vaccine[1][1]. We described elicitation of potentl...

Preprint released on enveloped virus-like particles and antigen quartets, from collaboration of Rory in our group with labs of Magnus Hoffmann and Pamela Bjorkman- keen to get comments
www.biorxiv.org/content/10.1...
#vaccines #synbio

07.11.2025 13:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Pleased to work with Addgene on this blog post relating to their fantastic resources.
#synbio

07.11.2025 13:12 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
Integrating chemistry, engineering and biology to create the next generation of vaccines Engineering Biology Interdisciplinary Research Centre

Delighted to invite you to the RSC symposium, β€œIntegrating chemistry, engineering and biology to create the next generation of vaccines” at Queens’ College Cambridge on 30th March 2026.
www.rsc.org/events/detai... @rsc.org #vaccines #immunology #synbio #biophysics

07.11.2025 13:02 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

How to make a NanoBondy- looking forward to your feedback on Lasya's preprint: www.biorxiv.org/content/10.1...

19.06.2025 16:13 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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My perspective is online from today on the power of a few good reactions: What is Click Biology? What can it do for you? What can you do for Click Biology? Keen to discuss.
rdcu.be/erMjs
#synbio @rsc.org #chemistry

19.06.2025 13:47 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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a cartoon drawing of a virus with a face on a yellow background ALT: a cartoon drawing of a virus with a face on a yellow background

Here is our paper on generating a Monkeypox vaccine candidate
www.nature.com/articles/s41...
led by Bernie Moss lab. Plug-and-display VLPs give a high level of protection, beating the standard Vaccinia-based vaccine. #mpox #vaccines #synbio

06.06.2025 11:05 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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A platform for SpyCatcher conjugation to native antibodies Protein–antibody conjugates represent major advancements in targeted therapeutics. However, platforms enabling β€˜off-the-shelf’ antibody conjugation are seldom reported. The SpyTag/SpyCatcher system, k...

Buy yourself an antibody➑️Clever chemistry from the Spring lab (tetraDVP) πŸͺ„SpyTag is coupled at the hinge and then the fun can begin...
Great collaboration along with @claudiadriscoll.bsky.social‬
pubs.rsc.org/en/content/a...
#synbio #antibody #biotech

19.05.2025 13:46 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Centre Seminar Series Invited external speakers 2025

Looking forward to speaking at Edinburgh Centre for Engineering Biology
tomorrow, 9:30am in Waddington Building biology.ed.ac.uk/centre-engin...

16.04.2025 11:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excellent opportunity in our Department and please tell others. Department includes people working on engineering biology, bionanotechnology, vaccines, biologics so many broad interests.
#biotech #synbio

16.04.2025 11:05 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congratulations! Well deserved.🌠

16.04.2025 10:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Youngsters got no patience these days. Now it's buy your DNA, in vitro express, SpyBLI for Kd, voilΓ !

20.03.2025 23:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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πŸ“’ Abstract submission for BSI Oxford and @immunologyoxford.bsky.social 's #OIS25 Symposium closes NEXT WEEK (7 Feb)

Don't miss your chance to take part in this celebration of the outstanding #immunology research happening across Oxford πŸ’«

Submit your abstract here πŸ‘‰ bit.ly/4elJmnG

30.01.2025 14:53 β€” πŸ‘ 8    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

This is a great BBC series on Secret Cambridge and includes the Cambridge spies, Olympics, why Cromwell's head in a biscuit tin etc.

06.02.2025 14:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I love it- that's wild.

06.02.2025 14:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Look out for these- will be great!

06.02.2025 14:20 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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How to find the best partners and strike a pose at the cell membrane?
See lab's recent review with @claudiadriscoll.bsky.social www.sciencedirect.com/science/arti... #synbio #antibody #biotech

06.02.2025 13:58 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Followed by Lasya Vankayala and Ginevra Camboni showing work using the Neisslock system to improve CAR-T therapies for solid tumours, and a high-throughput platform for engineering enzyme replacement therapies.

27.11.2024 15:15 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0