Christoph Schwarz

Thanks to @asnpublications.bsky.social for highlighting our feature on a new syndrome of renal tubular alkalosis! www.kidneynews.org/view/journal... @nu-nephrology.bsky.social @nufeinbergmed.bsky.social

doi.org/10.1172/JCI1....
distal renal tubular alkalosis - I have been waiting for this publication for years😉

New episode of Channel Your Enthusiasm, part 2 of 3 on metabolic acidosis. Episode with chapter art, chapters, and fully referenced

www.rosebook.club/episodes/202...

ENaC expression correlates with the acute furosemide-induced K+ excretion - PubMed Acute furosemide-induced kaliuresis differs greatly and depends on the a priori molecular expression level of ENaC. Remarkably, it can be even absent in animals fed a high Na⁺ diet, despite...

....at least in animals with high potassium intake furosemide works better to induce kaliuresis
pubmed.ncbi.nlm.nih.gov/33410279/

I can't this question, but it gives me a good excuse to mention the 1970s study by Oliver et al demonstrating that high levels of renin / aldosterone alone don't drive blood pressure. It's some combination of salt+RAAS+(?). pubmed.ncbi.nlm.nih.gov/1132118/ #NephJC

Now online in @ndt-era.bsky.social

Transition of pts with hereditary nephropathies from pediatric to adult care
from WG Genes&Kidney of ERA and ESPN

🧐To improve health outcomes, pt empowerment, and engagement for young people with CKD.

▶️ academic.oup.com/ndt/article-...

Development of respiratory alkalosis and increased anion gap metabolic acidosis in salicylate poisoning.

Core Curriculum by Biff F. Palmer and Deborah J. Clegg:

Mixed Acid-Base Disturbances: Core Curriculum 2025

bit.ly/Palmer25CC (FREE)

Kidney stone disease: risk factors, pathophysiology and management - Nature Reviews Nephrology This Review discusses the pathophysiology of kidney stone formation and examines the contribution of urinary risk factors and genetic variants. The authors also consider current approaches to the mana...

Kidney stone disease: risk factors, pathophysiology and management go.nature.com/47hmWEe

@danfuster.bsky.social
@sarahhowles.bsky.social

RIP Nicolas Madias

Of the Adrogue-Madias formula and much more

I don’t know he wrote three textbooks as a medical student!

www.kidney-international.org/article/S008...
In @kidneyint.bsky.social

#NephSky

Acid–base and electrolyte disorders in patients with hyperglycaemia: a monocentric, observational study - Clinical and Experimental Nephrology Background Acute hyperglycaemia is often accompanied by acid–base and electrolyte disorders as well as changes in serum osmolality which have a significant clinical impact. This study explores the pre...

Our new paper on acid base in hyperglycaemia is online - thanks to all authors
doi.org/10.1007/s101...

No stone goes unturned in the search for risk-associated variants in kidney stone disease—

@celovegrove.bsky.social @sarahhowles.bsky.social & team identify three biologic pathways that underlie ~11-19% of common causes of stone formation: buff.ly/INjAjLy

Advances in genetics have shed light on many pathways and genes implicated in pediatric kidney diseases, showing the pivotal role of genetic counseling and testing. kidney.pub/KN1707-11 kidney.pub/KN-Genetics #ASNKidneyNews

🧬Introducing our first-ever handbook of genetic nephrology, with free download until 8/2025

authors.elsevier.com/a/1lSgWzcYo6...

@andrewmallett8.bsky.social and I saw a gap in foundational reading of genetic nephrology and decided to gather articles that clinician and learners can all enjoy

swear I’m not making this up:

we’re called to see a patient with severe AKI and K=8.5 with ECG changes

exam shows a patient lying in bed next to a bannana

SIR, STEP AWAY FROM THE BANNANA

Sodium–chloride difference is not strongly correlated with base excess in chronic kidney disease: an anion gap problem - International Urology and Nephrology Introduction The prevalence of metabolic acidosis is high in patients with chronic kidney disease (CKD). For the diagnosis, a blood gas analysis is necessary, but not always available. The aim of the ...

link.springer.com/article/10.1...

Water and electrolyte homeostasis during decongestion in heart failure In heart failure, sodium retention generally occurs out of proportion to water retention and may occur disproportionate to chloride retention, requiring excretion of other cations (i.e. potassium, ma...

Water and electrolyte homeostasis during decongestion in heart failure - Van den Eynde - European Journal of Heart Failure - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
from heart to kidney - very nice review

JCI - Genetic variants predisposing to increased risk of kidney stone disease www.jci.org/articles/vie...
How many genes are necessary to create a kidney stone ?

torque teno virus 🦠 load predicts malignoma post kidney TX 💪

👏 carsten herz at #era25

viruses 🦠 can be 🦸 superheros
TTVbased immune monitoring
#TTVguide

Things We Do for No Reason™: Avoiding intravenous iodinated contrast material in patients with acute kidney injury or chronic kidney disease Click on the article title to read more.

This was a fun article to work on. Hope you enjoy it.

Things We Do for No Reason™: Avoiding IV iodinated contrast material in patients with acute kidney injury or chronic kidney disease Journal of Hospital Medicine
shmpublications.onlinelibrary.wiley.com/doi/10.1002/...

Update to our supersaturation and kidney stone risk assessment tool:

We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea!

ukidney.com/calculators/...

Kidney stone biology: insights from genetics url:https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf062/8132926
Very good overview on genetic mechanisms of kidney stone risk factors

Yeah we do need options for rare kidney disease

Options that are less expensive than buying a house. Every year. Forever.

(aka not Sparsentan)

It was a pleasure writing this piece with you @a1ismail.bsky.social, Bilal, and Dr. Rosa. I hope the article explains well the urine anion gap concept & its use in the proper context.
@asnpublications.bsky.social @nufeinbergmed.bsky.social @nu-nephrology.bsky.social
journals.lww.com/cjasn/pages/...

🧵 Introducing the EQUIL2 Urinary Supersaturation Calculator

A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature.

ukidney.com/calculators/...

1/3

Yes, this is very interesting

First tests of the #AI - enhanced robot nurse are under way in a project that is sure to revolutionise NHS staffing

(/is)

From histocompatibility to humoral theory, C4d, and now molecular diagnostics
The story of antibody-mediated rejection (AMR) keeps evolving.
🔍 MVI and microcirculation are now central to how we interpret rejection #NephJC

pubmed.ncbi.nlm.nih....

ADPKD Risk calculator.
This looks well done: halbritter-lab.github.io/adpkd-risk/

Hairy (Erdheim Chester) Rat kidney with Long Loops

A kidney-shaped kiwi.

Got fruit? A 🥝kiwi a day keeps the 🫘nephrologist away.
Stay healthy and have a nice weekend #NephSky #MedSky!

(Gloms reach a little too far down into the medulla, but hey, we don't even have a proper kidney emoji, so 🤷‍♂️)