Aisling Brady

More repressors 😅🔥

An unprecedented DNA recognition–mimicry switch governs induction in arbitrium phages Temperate phages integrate multiple information sources to regulate lysis-lysogeny transitions. SPBeta-like phages use arbitrium signalling and DNA damage to control repressor activity during lytic in...

Excited to share our latest work with @albertomarina.bsky.social and @avigdoreldar.bsky.social labs, where we decipher the mechanism by which SPβ-like phages sense the SOS response to control the lysis–lysogeny switch. www.biorxiv.org/content/10.1...

It was really great to meet you @vivekmutalik.bsky.social !

High-throughput DNA extraction from soil: experiences? best kits? best tools? If you had a decent chunk of money to throw at it, what system would you set up to make it fast and high quality? 🌾 🧪 🔬 🦠

🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.

Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.

A thread 1/8

Collage with headshots of ten individuals with a message announcing 'Prize Winners 2026 – Presenting at Annual Conference 2026.'

The Microbiology Society is pleased to announce the winners of our 2026 Prizes! The winners will be awarded and deliver Prize Lectures at Annual Conference 2026 in Belfast from 13–16 April. Find out more about it: microb.io/PrizeWinners.... Meet the winners below. #Microbio26

MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Liverpool on Fin... PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...

🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟‍♂️

Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...

Theres still time to apply for our PhD project on UPEC/immune cell interactions. Deadline December 4th

A person gestures while discussing a research poster with another attendee at a conference, with text announcing the Microbiology Society Annual Conference 2026 in Belfast, UK, from 13–16 April.

Final call! Abstract submissions for Annual Conference 2026 close at 23:59 GMT tonight. Submit your work and join us in Belfast: microb.io/AC26Abstracts #Microbio26

Salmonella multimutants enable efficient identification of SPI-2 effector protein function in gut inflammation and systemic colonization - Nature Communications Intracellular Salmonella enterica uses a type III secretion system to secrete more than 30 effector proteins into host cells. Here, Newson et al. generate six mutant strains deficient in different set...

Excited to share our latest work, where we create Salmonella mutants deficient for cohorts of SPI-2 T3SS effectors. These strains can be used to efficiently identify particular effectors that contribute to SPI-2 phenotypes doi.org/10.1038/s414...

Intracellular Salmonella hijacks the mitochondrial citrate carrier to evade host oxidative defenses - Nature Communications In this study, the authors show that Salmonella enterica serovar Typhimurium co-opts the host mitochondrial citrate carrier (CIC) to regulate the redox state of its vacuole, facilitating intracellular...

Intracellular Salmonella hijacks the mitochondrial citrate carrier to evade host oxidative defenses
www.nature.com/articles/s41...

Night view of Belfast City Hall illuminated with colourful lights, promoting abstract submission closing for Annual Conference 2026 at ICC Belfast from April 13-16.

One week to go! Abstract submissions for Annual Conference 2026 close at 23:59 GMT on Tuesday 11 November. If you study microbes, there’s a home for your work at #Microbio26
Submit your work to one of >20 available sessions at: microb.io/AC26Abstracts

CVR PhD student Emma Davies stood left of a bright blue Microbiology Society banner with her Early Career Microbiologist of the Year certificate, with Microbiology PhD student Phoebe Crossley stood right of the banner with her third place certificate.

🆕 | @uofgsii.bsky.social postgrad researchers have taken top honours in the @microbiologysociety.org Sir Howard Dalton Early Career Microbiologist of the Year competition.

Emma Davies (@cvrinfo.bsky.social) was named winner, with Phoebe Crossley (Microbiology) 3rd.

🔗 www.gla.ac.uk/schools/infe...

Excited to see the fantastic work you all do on this project!

I am delighted to be a co-investigator on this newly funded Wellcome Discovery Award. Excited to begin work with the team (including those not on Bluesky!)
@jayhinton.bsky.social @roygoodacre.bsky.social @lisamaierlab.bsky.social @blancaps.bsky.social

A news title card with a transparent image of salmonella bacteria against a navy blue background. The text reads '£4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella' in white.

NEWS | Professor @jayhinton.bsky.social and an international team have been awarded £4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella

🔗 bit.ly/4hujsRG

@livuninews.bsky.social | #TeamLivUni

Non-conjugative plasmids limit their mobility to persist in nature Sabnis et al. explain why non-conjugative plasmids move at a low rate in nature. While increased mobility can easily evolve by incorporating phage DNA into plasmids, this is disadvantageous because it...

New paper with my (amazing) friend and mentor @jrpenades.bsky.social
Really looking forward to see what plasmid aficionados think of this one!!
With @asantoslopez.bsky.social @wfigueroac3.bsky.social Akshay Sabins and others
www.cell.com/cell-reports...

This is really exciting work. Congratulations!!!

After being with the journal since its very inception, the time has come for me to step back from Microbial Genomics. This is a wonderful opportunity to have a leadership role in one of the leading journals for microbial genomics research

microbiologysociety.org/news/society...

Why not apply for a Microbiology Society grant to support your attendance at @shigellameeting.bsky.social?

microbiologysociety.org/grants/all-g...

Beautiful 😍

Happy Postdoc Appreciation Week! 💙

To celebrate postdocs we've teamed up with @proteintech.bsky.social to organise free social events for staff and students at universities.

Register for a free event near you:
pintofscience.co.uk/paw/

#NPAW2025 #CelebratePostdocs

cf-PICIs make their own capsids, steal phage tails and jump across species 😱

Spectacular - congrats Lingchen!

Ah thank you! One of those was already on my list 🙏

What is everyone's favourite review on anti-phage/defence systems? Ideally as an introduction to the concept/key systems for undergraduate level without expertise in phage biology #MicroSky #PhageSky

A huge thanks to the @microbiologysociety.org for their support with my External Event Grant! Attending this conference has been hugely impactful for me at this stage in my career and I’m very grateful 🙏 #ECR #MicroSky

Back to work this week after a fantastic time in New Hampshire for the GRS/GRC Salmonella 2025! My head is absolutely buzzing with new ideas 🤩💡 #GRC #Salmonella #MicroSky

@milja001.bsky.social @citizenphage.bsky.social @phagedirectory.bsky.social

#phagesky

I am looking for phages infecting Streptococcus pneumoniae to test a phenotype - does anyone have some and willing to share ?

Repost appreciated :)