Nina Cabezas-Wallscheid

Had such an amazing time at the Presidential Dinner #JSH2025 in Kitano, Kobe! Wonderful chats and discussions with hematology/oncology colleagues, exquisite cuisine, and a stunning night view—plus, of course, delicious Kobe beef and whiskey!
@ninacabezas.bsky.social
@einsteinmededu.bsky.social

Wonderful start to #JSH2025 (Japanese Society of Hematology, Kobe) at the speaker reception! Enjoyed great chats with many leading Hem/Onc clinicians and scientists. Excited for three days of hematology science, new connections, and reunions with old friends! @ninacabezas.bsky.social

Thanks for your visit and the awesome talk!!:))

Thanks @adlunglab.com for sharing!:)

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells Nature Cell Biology - Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia,...

Ageing & leukemia reshape metabolism of hematopoietic stem and progenitor cells. Mapping lipidomic and metabolomic shifts in human bone marrow, spotlighting choline as a key player in stemness to restore physiology!
@natcellbio.nature.com @ninacabezas.bsky.social
doi.org/10.1038/s415... 🧪

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...

🍹 @ninacabezas.bsky.social & co combine #metabolomics, #lipidomics and transcriptomics of #hematopoietic stem and progenitor cells during differentiation, #aging and #leukemia, finding a role for choline and showing that supplementation enhances stemness.
bit.ly/3H98V0U

So cool! A Podcast of our work! Thanks for the highlight :)

🗞️Do you want to meet and chat with our stem cell editor @slefkopoulos.bsky.social about your work for our journal? He will be there!
Register now for the FEBS Workshop on Aging in Hematopoiesis that will take place in Crete on October 20-24. aginginhematopoiesis2025.febsevents.org

Thank you very much Stelios!!:))

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...

🥂Congratulations to @ninacabezas.bsky.social & co for their new study in @natcellbio.nature.com combining #metabolomics, #lipidomics and transcriptomics of #hematopoietic stem and progenitor cells during differentiation, aging and leukemia.
bit.ly/40rfNx3

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...

Really valuable resource in @natcellbio.nature.com from @ninacabezas.bsky.social and team - Metabolomic and lipidomic profiling of human hematopoietic stem and progenitor cells:

www.nature.com/articles/s41...

Thank you Vijay!!!! Highly appreciated:)))

Mapping the metabolism of blood stem cells Researchers at the Max Planck Institute of Immunobiology and Epigenetics and ETH Zurich have created the first comprehensive metabolic profile of human blood stem cells. This opens up new possibilitie...

The first comprehensive map of HSC metabolism. 😱

The team of @ninacabezas.bsky.social published the first integrated map detailing metabolic & molecular changes in human blood stem cells as they age, specialize, or turn cancerous with many astonishing insights

More in @natcellbio.nature.com or ⬇️

Mapping the metabolism of blood stem cells Researchers at the Max Planck Institute of Immunobiology and Epigenetics and ETH Zurich have created the first comprehensive metabolic profile of human blood stem cells. This opens up new possibilitie...

Here our press release :)) www.ie-freiburg.mpg.de/6049881/news... thanks Marcus!!

BIG THANKS to the amazing collaborations that made this study possible!

We developed two novel low-input metabolomics&lipidomics methods(3K&5K cells)to tackle these questions! Among our findings: dietary-derived choline plays a key role in regulating the stemness of both young and aged HSCs!

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...

🔥NEW paper from our lab! Ever wondered how the metabolite/lipid composition of human bone marrow HSCs changes during differentiation,aging,AML? Check our work www.nature.com/articles/s41... driven by the brilliant Marialena & Maricarmen with Jörg! @mpi-ie.bsky.social @ethz.ch @natcellbio.nature.com

A vitamin A metabolite can regulate the activity of hematopoietic stem cells and thereby reduce inflammation after a heart attack, ultimately improving heart function in the long term. © Artist: Youssef Youssef

Wow. 🥳 The recent cardio paper by @ninacabezas.bsky.social lab got 2️⃣ beautiful highlights.

… one by Nature Cardiovascular Research nature.com/articles/s44...
and a second review by Science Immunology
science.org/doi/10.1126/...

Congratulations to team for this fantastic recognition! 🥇🥈

👏🏻👏🏻👏🏻

:)))

Full house for the keynote talk of @ninacabezas.bsky.social in the 2nd #YERM session of today 😍 She shared some intriguing insights on the role of Vitamin A in HSCs!

#EHA2025 #youngEHA

Consider attending the MOPITAS autumn school on Spatial Transcriptomics in Munich with expert lectures and hands-on sessions for all steps of spatial transcriptomics data analysis.
event.sdu.dk/mopitas-scho...

A year of stem cell and developmental biology In recent years, the field of stem cell and developmental biology has seen remarkable breakthroughs that have deepened our understanding of how organisms ...

Traveling to the @isscr.org meeting in HK soon? Feeling like browsing through important #StemCell work published during the past year on your way there? Take a look at our collection of papers published across @natureportfolio.nature.com during the past 12 months!

www.nature.com/collections/...

Get well very soon Stelios! :( 💪🏻

A very inspiring and motivating coffee with Dr. @ninacabezas.bsky.social! Thank you very much for your time and for the excellent talk on the regulation of hematopoietic stem cell dormancy at @cbm-csic-uam.bsky.social

Massive congraaaaats to Julian on an awesome PhD defense (with honors)!!! :)) Couldn’t be prouder — incredible job and so well earned!!!🥳👏🏻😎 @mpi-ie.bsky.social @sgbmfreiburg.bsky.social @cibss.bsky.social

Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study - Nature Cell Biology Rettkowski, Romero-Mulero et al. show that myocardial infarction impacts bone marrow haematopoietic stem cells and leads to inflammatory myelopoiesis, which can be dampened by treatment with 4-oxo-ret...

☕@ninacabezas.bsky.social, Heidt & co show that 4-oxo-retinoic acid promotes #cardiac recovery after myocardial infarction by modulating #hematopoietic stem cells. #preclinical
bit.ly/4iXb2Cx

The results are in 🗳️ Congratulations to our incoming 2025-2026 Board of Directors who will start their terms at the conclusion of #ISEH2025🏯 in September! 👏

Trainees - it's not too late to sign up for the Career Fair! Join us for this free event to meet expert faculty hiring from around the world. Registration closes 15 April at 09:00 CDT. www.iseh.org/careerfair2025

Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis - Nature Communications Germ layer specification during zygotic genome activation is regulated by chromatin state. Here, the authors use single-cell multiome profiling in Drosophila to show that H3K27me3 and H3K27ac at cis-r...

Exciting news! Our latest work in the Nicola Iovino Lab, “Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis,” is now published in Nature Communications!
www.nature.com/articles/s41...