@achemsynbio.bsky.social
Professor @BostonCollege Chemical Biology, Synthetic Biology, Directed Evolution, Expanding the genetic code https://sites.google.com/a/bc.edu/thechatterjeelab/home https://scholar.google.com/citations?user=zeSNxNcAAAAJ&hl=en
Thanks, André!
03.10.2025 21:06 — 👍 1 🔁 0 💬 0 📌 0
Excited to share our work with Eranthie Weerapana and Tim van Opijnen, co-led by Conor Loynd, Soumya Roy, and Sarah Canarelli! We introduce a new generation of BONCAT tools for the versatile characterization of newly synthesized proteins in pathogenic bacteria. rdcu.be/eI4M5
02.10.2025 14:10 — 👍 22 🔁 4 💬 0 📌 1🚀 Our new paper is out @natmethods.nature.com!
Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.
🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/
Faculty opening in Cornell Chemistry at the Assistant Professor level in the area of chemical biology, broadly defined! academicjobsonline.org/ajo/jobs/30338 #chemjobs
25.08.2025 20:30 — 👍 49 🔁 52 💬 1 📌 4Thrilled to see this in print! Co-translational incorporation of a noncanonical monomer into a protein, followed by its triggered post-translational chemical rearrangement, yields novel backbone modifications. One step closer to novel genetically encoded biopolymers!
21.08.2025 22:24 — 👍 5 🔁 1 💬 0 📌 0
Continuous evolution in E. coli using an orthogonal replisome www.science.org/doi/10.1126/...
08.08.2025 23:36 — 👍 5 🔁 1 💬 0 📌 0Cool technology from the @chembiobryan.bsky.social lab for high-throughput discovery of protein binders
06.08.2025 23:10 — 👍 3 🔁 0 💬 0 📌 0Congratulations, Rita!
02.08.2025 00:57 — 👍 1 🔁 0 💬 0 📌 0
Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
Congratulations, Simon!
07.06.2025 13:50 — 👍 0 🔁 0 💬 0 📌 0
The further a researcher or inventor moves from their previous work, the less cited their latest work will be
https://go.nature.com/44VjEW9
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
I am a big believe of doing your own research and checking facts and sources.
BUT THE BIG PROBLEM IS THAT A POST FROM SOME DUDE ON THE INTERNET SHOULD NOT BE WEIGHTED THE SAME AS INFORMATION FROM SOMEONE WHO HAS SPENT DECADES STUDYING AN ISSUE.
Chemists Stuart Schreiber of Harvard University and Arena BioWorks and Peter Schultz of @scripps.edu will split the 2025 Welch Award in Chemistry for their work in the field of chemical biology. cen.acs.org/people/award... #chemsky🧪
22.05.2025 19:51 — 👍 55 🔁 11 💬 1 📌 1
They're terminating OPT.
Today the nominee to head USCIS stated directly: he will end Optional Practical Training, the single largest channel for high-skill immigrants to work in the US.
6 weeks ago I warned about this & summarized the research on impacts of this drastic action—> @piie.com
Happy to share a paper from our group on "MapID-tRNA-seq" for confidently identifying modifications by RT mutation signatures in human tRNAs. This method will enable future discoveries of modifications' occurrence and functions in tRNA biology and diseases. www.cell.com/cell-chemica...
16.05.2025 03:58 — 👍 20 🔁 4 💬 1 📌 0
A chocolate cake with red and white decorations and lit candles shaped as the number 75. Bold text reads: ‘The NSF Turns 75 Today. What has it done over the past 7 decades?’ The background is a celebratory red with a spray-paint texture.
HAPPY 75th, NSF!
We’re celebrating this milestone by highlighting some of NSF’s most transformative accomplishments—innovations that have shaped our world and continue to drive progress in health, technology, the environment, and beyond.
Read on 🧵(1/11):
🧪 Though a doubling of NSF's budget might seem far-fetched, that's exactly what Congress said what's needed to maintain national competitiveness in science & tech.
From the bipartisan CHIPS and Science Act of 2022:
Escherichia coli with a 57-codon genetic code https://www.biorxiv.org/content/10.1101/2025.05.02.651837v1
02.05.2025 21:09 — 👍 15 🔁 9 💬 0 📌 3
BREAKING: Reports that Trump would try to cut NIH's budget by 40% have come true.
The request released moments ago would:
- Cut $18 BILLION to NIH's $47b budget
- Eliminate NIMHD, NCCIH, FIC
- Collapse ICs into five 'focus areas'
There's also a long screed about NIH's deficiencies.
Very nice work @kunjapur.bsky.social. Congratulations to the team!
01.05.2025 19:10 — 👍 1 🔁 0 💬 1 📌 0
Badass Surgeon Puts On Fingerless Latex Gloves Before Operating
Badass Surgeon Puts On Fingerless Latex Gloves Before Operating
28.04.2025 16:00 — 👍 7182 🔁 720 💬 91 📌 44
So excited for the annual student-organized Chemistry-Biology Interface symposium today! Amazing lineup including @hsulab.bsky.social @achemsynbio.bsky.social, Sloan Devlin (Harvard), & Nick Agard (Genentech) + stellar Cornell student and faculty speakers. Looking forward to some great science!
26.04.2025 11:27 — 👍 16 🔁 3 💬 0 📌 1SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web.
chemsymposia.com
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.
www.training.nih.gov/research-tra...
total; nsf grfs 2021-2015
nsf GRFS by major field 2021-2025
Quick look at NSF GRFPs awarded 2021-2025. Overall 50% drop from 2024, with biggest absolute decreases in engineering, life sciences and chemistry.
(sorry about the meh viz, in a hurry)
Congrats to lead author Doug and team on their new preprint, which describes a genome mining strategy to find non-canonical amino acid-based secondary metabolites outside of RiPP and NRPS pathways! Read more below: chemrxiv.org/engage/chemr...
23.03.2025 22:20 — 👍 17 🔁 6 💬 0 📌 1Congratulations @jeremybaskin.bsky.social! Great news!
22.03.2025 20:14 — 👍 1 🔁 0 💬 0 📌 0
Cool work from @klanglab.bsky.social group on identifying and engineering a novel bacterial transporter to import challenging noncanonical amino acids in E. coli, enabling improved incorporation efficiency proteinsproteinshttps://www.biorxiv.org/content/10.1101/2025.03.06.641855v1.abstract
20.03.2025 22:36 — 👍 9 🔁 5 💬 0 📌 0
