Neftaly Cruz Mireles

Thank you @marischuster.bsky.social for accepting our invitation and for sharing with us your exciting science. The world of proteases is fascinating!

I was honored to be invited by the postdocs at the University of Zürich for a visit and a talk.
The full schedule was far too short for so much great science and Zürich in spring is just lovely.
Special thanks to @giurassicpark.bsky.social for the impeccable organization!

It was a pleasure to host you, @marischuster.bsky.social. Thank you for all the inspiring scientific discussions and sharing your protease fascination with us.

Postdoctoral Researcher (Charpentier Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Charpentier Group at the John Innes Centre, working on cutting-edge science in the field of plant calcium signalling.

My lab at the JIC is recruiting 3 PDRA:
🔹 Bioinformatics / AI
🔹 Molecular Biology / Genetics
🔹 Proteomics
Programme funded by the Novo Nordisk Foundation.
📅 Closing date: 27 February
Apply via JIC website:
www.jic.ac.uk/vacancies/
Please share with outstanding candidates. 🙏

Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunity👇🏾

Fantastic opportunity to join this exciting new group led by @delaconcepcionjc.bsky.social . Cryo-ET of infection-related development in pathogenic fungi - including rice blast - an exciting, game-changing prospect. Apply below 👇

PhD position in biology (m/f/d) (1/2026) Leibniz Institute of Plant Biochemistry (Halle) offers a PhD position in Biology

Please share! We are looking for a PhD student (4 years) starting from 01/05/2026 at @ipbhalle.bsky.social!
If you are interested in plant immunity, receptor biochemistry and evolution, consider applying! Deadline 09/03/2026.

Application portal: ipb-halle.mhm.jobs/10-phd-posit...

📢 Job alert! @delaconcepcionjc.bsky.social, junior group leader at #ZMBP, has 2 open positions (PhD and postdoc) to investigate appressoria formation in plant pathogenic #fungi using #cryoEM and #cryoET
#EmmyNoether #MPMI #plantscijob
More info 👇

Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

Fig. 2 (shortened, full legend in paper): Structurally characterized M. oryzae effectors in complex with the HMA or HMA-like domains of host target proteins and ID-NLRs. Crystal structures of (A) AVR-PikF with the HMA-like domain of OsHIPP19 from rice (7B1I) (Maidment et al., 2021); (B) APikL2A with the HMA-like domain of sHMA25 from foxtail millet (7NLJ) (Bentham et al., 2021); (C) Pwl2 with the HMA domain of OsHIPP43 from rice (8R7D) (Zdrzałek et al., 2024); (D) AVR-PikD with the HMA-like ID of Pikp-1 from rice (5A6W) (Maqbool et al., 2015); (E) AVR-Pia with the HMA-like ID of Pikp-1 (6Q76) (Varden et al., 2019); (F) AVR1-CO39 with the HMA-like ID of RGA5 from rice (5ZNG) (Guo et al., 2018). Complexes are displayed such that the HMA/HMA-like domains are in equivalent orientations. Domains from HPP/HIPP host targets are coloured light green. Domains from ID-NLRs are coloured dark green.

⚙️🦠 REVIEW 🦠⚙️

Turley & Faulkner explore the function of plant heavy metal-associated domain-containing proteins and speculate about their functions at plasmodesmata by drawing from plant–pathogen interaction studies.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪 Christine Faulkner

🗣️ 𝐼𝑛 𝑐𝑜𝑛𝑣𝑒𝑟𝑠𝑎𝑡𝑖𝑜𝑛 𝑤𝑖𝑡ℎ 𝐃𝐫. 𝐂𝐲𝐫𝐢𝐥 𝐙𝐢𝐩𝐟𝐞𝐥

Cyril Zipfel, a leading voice in plant immunity, reflects on plant immune recognition, his scientific journey, and what’s next for the field 🌱🧬

interviewed by @luisdeluna.bsky.social

👉 doi.org/10.1111/tpj.70688

Uppsala in late autumn

Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...

1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577

The fourth lecture of the course is now available on YouTube :) We will review how Transformers and modern LLMs work
youtu.be/vUpb6O6T2yQ

Slides
drive.google.com/file/d/1y2Vj...

For now, the English version is only available through the automatic translation of the subtitles.

New lab preprint - Common and rare variant studies for the same trait identify different genes and here Diederik Laman Trip developed a protein network AI enconding to investigate if traits studied by different approaches converge on the same molecular pathways
www.biorxiv.org/content/10.6...

Very greatfull to work with this brilliant and diverse bunch that make up the #proteomics team @thesainsburylab.bsky.social. #Awayday. 🇨🇦🇫🇴🏴󠁧󠁢󠁳󠁣󠁴󠁿🇬🇧🇵🇭🇬🇭🇨🇳🇨🇿🇩🇪🇳🇱

Spooky season has arrived! 👻
We held our annual Pumpkin Carving Competition at @thesainsburylab.bsky.social —vote for your favourite carve! 🎃🕯️

New pre-print from the team!

The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.

Have a read!

#PlantScience
@johninnescentre.bsky.social

Excited to visit @ihsmumacsic.bsky.social this Friday. Looking forward to connecting with everyone there!

Muy contento de visitar @ihsmumacsic.bsky.social en Málaga. Nos vemos el viernes!

Bottom-up proteomics under acidic conditions using protease type XIII from Aspergillus saitoi Bottom-up proteomics is a powerful technique for comprehensive analysis of proteins by proteolytic cleavage followed by liquid chromatography/tandem mass spectrometry to identify the resulting peptide...

Bottom-up proteomics under acidic conditions using protease type XIII from Aspergillus saitoi
www.biorxiv.org/content/10.1...
#Proteomics

See you all in Prague! 🌱🧬🥳

Changes to the 2026 and 2027 Work Programmes With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

Increasing the time limits post PhD for ERC starting grant applications is a bad idea. It will mean fewer junior PIs getting an ERC at the start of the group. Those complaining about the previous time limits will not really benefit. The competition will be higher.
erc.europa.eu/news-events/...

Maternal control of RNA decay safeguards embryo development As in mammals, the plant embryo is surrounded by maternal tissues that provide protection from the external environment. In angiosperms, a double fertilization process results in the formation of a di...

🚨 Preprint alert!!
Thrilled to share our new story where we report the discovery of a new sporophytic maternal-effect mutant in Arabidopsis. 🧵
www.biorxiv.org/content/10.1...

Excited to share some of our work on ubiquitin at this seminar!

Hi everyone! I’m new to Bluesky. At the beginning of the year, I moved to Zurich @UZH_en to start a postdoc with #CyrilZipfel and @pedrobeltrao.bsky.social, investigating protein phosphorylation in plants 🌱

If you’re nearby or working on something similar, let’s connect 😀