Christian Frezza

congrats on your paper by the way 🎉

I have noticed low engagement here, in particular for science papers, while a lot of the politics found on X is gradually moving here too. Is this my impression only? I am considering moving completely to LinkedIn.

Good morning, all! The past week has seen some fantastic papers in #cancermetabolism and #mitochondrialbiology. Check them here: biomed.news/bims-camemi/... Biomed News #keepreading

"Time, which changes people, does not alter the image we have of them."-Marcel Proust

Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction Lisci et al. present a unified model revealing how cells escape glutamine addiction, a metabolic vulnerability of several cancers. Combining systematic genetic and nutrient screens, they show that bio...

Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction: Molecular Cell www.cell.com/molecular-ce...

Good Sunday, all. There is a wonderful curated selection of papers in #cancermetabolism and #mitochondrialbiology here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading

The real truth, that dare not speak itself, is that no one is in control. Absolutely no one.

Terence McKenna

Good morning, all! Here is a beautiful selection of papers in #cancermetabolism and #mitochondrialbiology. Don't miss it! biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading

"For everything you do, there will be a last time that you do it."-William B. Irvine

it was on purpose. I am glad you spotted it, maybe you can also read the piece. Also, I thank you for the judgment on my accuracy....well done 👍

Thinking Like a Scientist, Part Three: Hypothesis Retrofitting Scientific papers are more complex than ever, but are we gaining deeper understanding or losing sight of the hypothesis? In this third part of Thinking like a scientist, I reflect on data-driven scien...

Papers are increasingly challenging to navigate, not only because of the sheer volume of data they contain but also because of their structure. This is a delicate point of discussion that we, as a community, should address. I would love hearing your views on this.

network.febs.org/posts/thinki...

Chrysanthi Moschandrea and I have developed a new conceptual framework for understanding the role of metabolism in cancer, which we term metabolic permissiveness. We are eager to hear your thoughts on this topic.

genesdev.cshlp.org/content/earl...

Glucose deprivation drives LIF-dependent lung cancer - Nature Metabolism Glucose deprivation triggers the secretion of the cytokine LIF, which promotes angiogenesis and immune suppression in lung cancer models.

A particular mention to @crismunozp.bsky.social paper, which I sadly missed last week! www.nature.com/articles/s42...
Congratulations Cristina and team!

Good Sunday, all. Here is your weekly selection of papers in #cancermetabolism and #mitochondrialbiology. So many exciting findings!! biomed.news/bims-camemi/... @biomednews.bsky.social

Biomed News #keepreading

"I am a part of all that I have met."-Alfred Tennyson

sorry! misslinked! thanks for checking it

ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression - Nature The ZFTA–RELA fusion, an oncogene for ependymomas, promotes the production of itaconate, and its dependence on this metabolite represents a new therapeutic target for this cancer.

Activated ATF6α is a hepatic tumour driver restricting immunosurveillance

www.nature.com/articles/s41...

ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression - Nature The ZFTA–RELA fusion, an oncogene for ependymomas, promotes the production of itaconate, and its dependence on this metabolite represents a new therapeutic target for this cancer.

ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression

www.nature.com/articles/s41...

Happy Sunday egg-ficionados! Here comes your weekly issue of #cebooc:

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41606324/ by @brugueslab.bsky.social

Powered by @biomednews.bsky.social

Good Sunday, mitolovers. Here is the weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology, with truly remarkable papers: lnkd.in/e7HDuVuU @biomednews.bsky.social #keepreading

"Attention is the rarest and purest form of generosity."-Simone Weil

Good Sunday, all. Here is the weekly curated summary of papers in #cancermetabolsim and #mitochondrialbiology. Don't miss it! lnkd.in/e9QJz9AZ @biomednews.bsky.social #keepreading

"Start right now. Take a small step you can call your own. Don't follow someone else's heroics."-David Whyte

Whoa!! That's an amazing milestone, and well done for giving the community the opportunity to grow. The quality has been stellar!

Good Sunday, all! Here is the curated weekly collection of papers in #cancermetabolism and #mitochondrialbiology. Don't miss it; find it here: biomed.news/bims-camemi/... Biomed News #keepreading

"It's very simple to be happy. But it's very difficult to be simple." - Rabindranath Tagore

only 6!

Polyamine-dependent metabolic shielding regulates alternative splicing - Nature Polyamines prevent the action of kinases on acidic phosphorylatable motifs in spliceosomal proteins, thus providing a mechanism for metabolite-mediated regulation of alternative splicing in cells.

Polyamine-dependent metabolic shielding regulates alternative splicing

www.nature.com/articles/s41...

thank you for the chance of presenting our work!

Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsis - Nature Immunology Rathmell and colleagues show that metabolic reprograming of regulatory T cells is associated with severity of critical illness in patients with and without sepsis.

Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsis

www.nature.com/articles/s41...

Language model-guided anticipation and discovery of mammalian metabolites

www.nature.com/articles/s41...

that's a party!

does the list end at some point?

Good Sunday, all. Here is a great summary of last week's papers in #cancermetabolism and #mitochondrialbiology. Don't miss it! Find it here: biomed.news/bims-camemi/... Biomed News #keepreading

"Life isn't a dress rehearsal; this is it. It's your job to show up for this moment" Oliver Burkeman

Mitochondrial transfer from glia to neurons protects against peripheral neuropathy - Nature Mitochondria that are transported from satellite glial cells in dorsal root ganglia to peripheral sensory neurons through tunneling nanotube-like structures provide protection against peripheral neuro...

www.nature.com/articles/s41...

Mitochondrial transfer from glia to neurons protects against peripheral neuropathy - Nature Mitochondria that are transported from satellite glial cells in dorsal root ganglia to peripheral sensory neurons through tunneling nanotube-like structures provide protection against peripheral neuro...

www.nature.com/articles/s41...

Nutrient requirements of organ-specific metastasis in breast cancer - Nature How the complex interplay between multiple nutrients within the microenvironment dictates potential sites of metastatic cancer growth is explored.

www.nature.com/articles/s41...

congrats to the @mvhlab.bsky.social !!