🎓 PhD at IIMCB – Where Ambition Meets Discovery!

Check 14 positions in neuroscience, virology, RNA & cell biology. Join our vibrant, international research community in Warsaw! 🤝

🗓️ Apply: May 19 – June 1

🔗 tinyurl.com/phd-iimcb-2025

#PhD #Warsaw4PhD #PhDlife #PhDOpportunities

Scientists from the IIMCB described a new mechanism that improves the efficiency of mRNA-based therapies. The research findings will facilitate the development of novel therapeutics against cancers and infectious diseases.

#NaturePublication #mRNA #RNAResearch #IIMCB #FunduszeUE

#mRNA #vaccine stability and efficacy depends on its #polyA tail and is boosted by re-adenylation in #macrophages by my favourite enzyme TENT5A - in @nature.com by @pakraw.bsky.social and Seweryn Mroczek, Lab of RNA Biology - ERA Chairs Group @iimcb.bsky.social led by @andrzejdziembowski.bsky.social

Happy to share with you our new @nature.com story about the crucial role of TENT5A-mediated re-adenylation of mRNA COVID-19 vaccines in boosting their efficacy. We also show how important macrophages are in producing the antigen following vaccination. www.nature.com/articles/s41...

Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines @nature.com @andrzejdziembowski.bsky.social @pakraw.bsky.social
www.nature.com/articles/s41...

Transcriptomic profiling of individual bacteria by MATQ-seq - Nature Protocols Bacterial single-cell sequencing via MATQ-seq combines index sorting, random priming and rRNA depletion, and offers high cell retention and transcript capture rates, making it ideal for experiments wi...

If you want to do single-cell RNA-seq on your favourite bacterium, here‘s our detailed Nature Protocol for microbial MATQ-seq. It profiles up to 600 genes in a single bacterial cell!

www.nature.com/articles/s41...

My first (and probably the last), first-author @nature.com paper formally accepted. Huge effort of all people involved, mostly from the Laboratory of RNA Biology, IIMCB in Warsaw (all authors are from Polish institutions!). More details when the manuscript will be in press.

5′ terminal nucleotide determines the immunogenicity of IVT RNAs Abstract. In vitro transcription (IVT) is a technology of vital importance that facilitated the production of mRNA therapeutics and drove numerous breakthr

In vitro transcription (IVT) is a technology that facilitated the production of mRNA therapeutics and drove numerous breakthroughs in RNA biology. Our new study uncovers unexpected insights into the immunogenicity of in IVT RNAs. #RNA #IVT #Immunity

academic.oup.com/nar/advance-...

Exogenous RNA surveillance by proton-sensing TRIM25 Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens...

TRIM25 takes a centre stage! Right in the context of its RNA-binding role. Exogenous RNA surveillance by proton-sensing TRIM25 | Science www.science.org/doi/abs/10.1...

Home - 2nd Polish RNA Meeting

Dear Polish and European RNA Researchers,
Don’t forget to register for the 2nd Polish RNA Biology Meeting in Poznan, June 24-27! 🧬✨ It’s gonna be an incredible event with an AMAZING lineup of keynote speakers already confirmed! 🎉#RNA

👉 Register here: 2ndrna.web.amu.edu.pl