Léa Monge-Waleryszak

New pre-print from the team!

The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.

Have a read!

#PlantScience
@johninnescentre.bsky.social

14.10.2025 07:16 — 👍 77    🔁 53    💬 0    📌 0

New Article: "Vacuolar sorting receptors coordinate lytic vacuolar and autophagic transport for plant effector-triggered immunity" rdcu.be/eBbOG

VSRs orchestrate the vacuolar sorting of immune-related proteins and autophagic degradation of bacterial effectors in ETI.

18.08.2025 10:51 — 👍 6    🔁 3    💬 1    📌 0

Plant-associated fungi co-opt ancient antimicrobials for host manipulation Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...

📣 NEW PREPRINT 📝

We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...

cc @teamthomma.bsky.social

15.08.2025 07:46 — 👍 66    🔁 44    💬 1    📌 3

New preprint: In situ Architecture of #Plasmodesmata.

Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.

🔗 doi.org/10.1101/2025...

🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM

26.07.2025 15:38 — 👍 197    🔁 72    💬 9    📌 8

How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...

22.07.2025 18:42 — 👍 89    🔁 34    💬 11    📌 4

Are chromatin remodelling complexes targets of bacterial effectors PopP2 & XopJ6 ? Check out our work at #2025ISMPMI ! P-163 presented Wednesday afternoon by my amazing PhD supervisors Laurent Deslandes & Valerie Pacquit. @lipme-toulouse.bsky.social @ismpmi.bsky.social

15.07.2025 15:23 — 👍 11    🔁 7    💬 2    📌 0

Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants Robinson et al. identify pathogenic Pseudomonas viridiflava in wild Marchantia polymorpha liverworts and interrogate the mechanisms enabling virulence in non-flowering and flowering plants. Their resu...

Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants

Very happy to share the published version of our work on natural Marchantia-Pseudomonas interactions.

Out now in Current Biology: www.cell.com/current-biol...

01.04.2025 19:11 — 👍 65    🔁 37    💬 1    📌 2

Three ARID proteins involved in chromatin remodeling PEAT complexes are targeted by the Ralstonia solanacearum effector PopP2 and contribute to bacterial wilt disease The Ralstonia solanacearum effector PopP2 is a YopJ family acetyltransferase. PopP2 is known to dampen basal immune responses by acetylating defensive WRKY transcription factors, and probably by targ...

Love uncovering effector virulence strategies! 😀
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....

26.05.2025 11:06 — 👍 6    🔁 4    💬 0    📌 0

Exploring the untapped potential of single‐cell and spatial omics in plant biology Advances in single-cell and spatial omics technologies have revolutionised biology by revealing the diverse molecular states of individual cells and their spatial organization within tissues. The fie...

Direct link to review @newphyt.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...

22.05.2025 17:00 — 👍 13    🔁 6    💬 0    📌 0

Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature Demont et al. show that immune signaling induced by Toll/interleukin-1 receptor (TIR) domains, including EDS1 and the SA sector, is maintained at elevated temperatures (30°C), in contrast to signaling...

Very glad to see #HéloïseDemont PhD work online in @cp-cellreports.bsky.social! @lipme-toulouse.bsky.social #REACHteam

Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature: www.cell.com/cell-reports...

03.03.2025 15:10 — 👍 32    🔁 22    💬 1    📌 2

Results presentation

Annoncement of the obtention of the PhD by the president of the jury following the defense

Camille Puginier (PhD since January 17th 2025) and Léa Monge-Waleryszak (PhD since January 31st 2025)

Celebrations

My PhD defense was an amazing moment. Many thanks to members of my jury for examining my work and for this very enjoyable discussion:

C. Segonzac
@ifudal.bsky.social
MH. Lebrun
B. Szurek
V. Cotelle

Huge thanks to my increadible supervisors L. Deslandes & V. Pacquit for their unfailing support.

02.02.2025 16:15 — 👍 6    🔁 1    💬 0    📌 0

[#PhD] 👩‍🎓 Today Léa Monge Waleryszak defends his PhD on "Investigating the proximal proteomes of 2 YopJ family acetyltrasferases from 2 plant vascular pathogenic bacteria"
@ifudal.bsky.social

31.01.2025 12:37 — 👍 9    🔁 3    💬 2    📌 0