Gilbert C FAURE

Comprehensive single-cell analysis reveals mast cells’ roles in cancer immunity | Oncogene Mast cells, traditionally known for their roles in allergic reactions and pathogen defense, have been revealed to possess significant functional diversity within the tumor microenvironment (TME). Through single-cell RNA sequencing analysis across 15 solid tumors (385 samples from 264 patients), 10...

Comprehensive single-cell analysis reveals mast cells’ roles in cancer immunity | Oncogene

College endorses the British Society for Haematology’s report – “The Haematology Workforce, a comprehensive view” | Royal College of Pathologists (RCPath) The College is pleased to have endorsed the British Society for Haematology report “The Haematology Workforce: A Comprehensive View.” This report highlights the vital role of clinical pathology and laboratory services in the rapid diagnosis and management of haematological diseases. The report reveals the growing pressure on haematology professionals, as the gap between workforce capacity and clinical demand continues to widen. Supporting these findings, the College’s 2025 Workforce Census finds that 82% of haematologists believe current staffing levels are insufficient to ensure the long-term sustainability of services. The College agrees that robust workforce planning is essential to align haematology services with local and regional needs – factoring in population growth, diagnostic demand, evolving working patterns, and succession planning. Action and investment are urgently needed to future-proof the haematology workforce and ensure equitable access to high-quality care for all affected by blood diseases. Read more here: https://ow.ly/ptGN50X6bZL #Pathology #HealthcareWorkforce #RCPath #Haematology

College endorses the British Society for Haematology’s report – “The Haematology Workforce, a comprehensive view” | Royal College of Pathologists (RCPath)

Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans

💉 On this day in 1956, the polio... - Hashem Al-Ghaili

💉 On this day in 1956, the polio... - Hashem Al-Ghaili

Nobel Prize in Physiology or Medicine 2025 - Advanced information The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Nobel Prize in Physiology or Medicine 2025 - Advanced information

Europe PMC Europe PMC is an archive of life sciences journal literature.

Europe PMC

🌺Today is the big day – the 76th... - Wuhan University

🌺Today is the big day – the 76th... - Wuhan University

Confucius Quotes that he Didn’t Actually Say Discover the many Confucius quotes that have been wrongly attributed to the great philosopher, or simply misinterpreted by modern society

Confucius Quotes that he Didn’t Actually Say

Proverbes chinois (bilingue) | **话要少说，事要多做**

Proverbes chinois (bilingue) | **话要少说，事要多做**

Information Literacy Weblog: The information literacy landscape in Germany – challenges, best practices, and trends #ECIL2025 Nicolas Kusser , Gemeinsame Kommission Informationskompetenz von dbv und VDB and Sabine Rauchmann   from Universitätsbibliothek Augsburg spo...

Information Literacy Weblog: The information literacy landscape in Germany – challenges, best practices, and trends #ECIL2025

A fun paper to read. Check acknowledgments and footnotes below - this is a joke of course... except this "scientific" journal did not seem to care. Is anyone actually working at this publisher? Lin... A fun paper to read. Check acknowledgments and footnotes below - this is a joke of course... except this "scientific" journal did not seem to care. Is anyone actually working at this publisher? Link to this gem in comments. In case you have any doubt: ACKNOWLEDGEMENTS The author thanks ChatGPT for making up the experiment, generating the data, writing the article, and for creative suggestions for the alien experimental condition. The author thanks Dall-E for generating all images. FOOTNOTES Institutional review board statement: The study was reviewed and approved by the Telepathy & Alien Institutional Review board. Conflict-of-interest statement: Stan van Pelt is a science journalist, and not an active scientist. Data sharing statement: There is no data to share, since no real measurements have been done.

A fun paper to read. Check acknowledgments and footnotes below - this is a joke of course... except this "scientific" journal did not seem to care. Is anyone actually working at this publisher? Lin...

MILCLICKS - ⏳ One Month to Go! The countdown is on:...

MILCLICKS - ⏳ One Month to Go!

The countdown is on:...

The College’s Clinical Immunology Workforce Report finds critical staff shortages across services that diagnose and treat allergies, autoimmune diseases and immunodeficiencies.   Three quarters of ... The College’s Clinical Immunology Workforce Report finds critical staff shortages across services that diagnose and treat allergies, autoimmune diseases and immunodeficiencies.   Three quarters of UK immunology services report that they do not have enough staff to meet current clinical demand.   Dr Patrick Yong, Chair of the College Specialty Advisory Committee for Immunology, quotes: "This is a sobering report. Many services rely on goodwill and unpaid overtime to keep running. We urgently need to establish more training posts and focus on retaining experienced consultants to ensure safe, effective patient care.” Patients are facing delays to diagnosis and treatment, while consultants are at risk of burnout. The College is calling for more training posts, better support, and improved workforce planning. Read the full report and recommendations on our website. https://lnkd.in/eyavzHsp

The College’s Clinical Immunology Workforce Report finds critical staff shortages across services that diagnose and treat allergies, autoimmune diseases and immunodeficiencies.   Three quarters of ...

Five Laws of Media and Information Literacy | UNESCO Five Laws of Media and Information Literacy

Five Laws of Media and Information Literacy | UNESCO

Newfound immune cell in mice hints at why inflammation spikes with old age Pathogen-consuming cells found in fat tissue also play a part in lipid balance.

Newfound immune cell in mice hints at why inflammation spikes with old age

#lascam | Jean-Luc DELBLAT | 45 comments Le Monde qui a choisi Perplexity a du soucis à se faire Jérôme Fenoglio. Ce printemps, c’était l’une des meilleures IA car elle moissonnait (LLM) les articles du journal où j’ai travaillé, ignorant l’actu chaude que je retrouvais sur l’appli du Monde où je suis abonné. J'avais testé en avril 2025 dix IA en préparation d’un Café IA du Conseil de l'intelligence artificielle et du numérique à Viva Technology avec Gilles Babinet. Perplexity est devenue la pire des IA (46% d’erreurs 🤯) car elle moissonne désormais aussi le web et ses usines à troll et malinfo dans un contexte de guerre hybride mondiale. Perplexity ne retrouve même pas dans le moteur du Monde les articles publiés la veille ! 🤪 La fabrique de l’info, c’est bien croiser comme à Combat ses sources et non produire du hachis pour temps de cerveau disponible Jean-Clément Texier ? Dites-moi... 😅 . Et c’est encore Google qui va plier le match avec Gemini, comme en 1998, quand nous avons créé Hachette.net au tout début de Club Internet (nous étions huit très à l’étroit sur un plateau encombré de modems bruyants 56K 🙃). Mon guide du web interactif a été enterré par Lagardère deux ans avant l’arrivée de Google et la disparition de ses moteurs concurrents, dont nous faisions partie avec Exalead... Je suis parti travailler au Routard, d’autres aux US à San Francisco... 😜 Donc je vais utiliser comme IA Gemini tant que l’UE ne sera pas unie pour en créer une, excepté pour mettre des amendes salées (justifiées mais illusoires) à ses brillants concurrents. Ceci risque d’être le dernier acte de l’enterrement des media déjà annoncé en 2011 par Bob Woodwards, après le print et la TV pour seniors où exercent de grands professionnels certes mais dépassés et écrasés par Youtube et ses Tubeurs, première chaine de France, désormais parrain des jeunes pousses du prix Albert Londres à l’initiative de Romain Cabrolier et #LaScam où je fus commissaire de l’écrit et qui a su dès 2000 s'adapter aux usages du digital... "First winner, second looser !", comme on disait avant la première bulle des TIC de 2000 bientôt engloutie par celle de l’IA selon Sam Altman fondateur d’OpenAI... La majorité des cadres aux US n’utilisent pas l’IA jugée défaillante. La majorité des jeunes français déclarent vouloir se passer d’internet jugé anxiogène, energivore, destructeur d’emplois et chronophage (cf Le Monde)... Bon je retourne sur FB, LI, X, Insta, Youtube, Google où je m’informe au quotidien 1h matin et soir selon mon smartphone. Je ne regarde plus la TV. Le reste est consacré aux itw IRL, à la lecture, l’écriture et aux flâneries créatives.... Ces instruments digitaux sont merveilleux quand on trie, qualifie et organise drastiquement ses contacts et ses journées de travail. Cela s’appelle du journalisme et j’ai été formé à la plus belle école : celle de mon ami et père de substitution Bernard Thomas, REC et critique du Canard Enchainé auquel je rends hommage. On s’est bien marrés et ce n’est pas près de s’arrêter... | 45 comments on LinkedIn

#lascam | Jean-Luc DELBLAT | 45 comments

#sciencereview | Science Magazine | 19 commentaires Researchers in a new #ScienceReview examine the influence that biological sex exerts on the immune system and immune-related diseases. Learn more: https://scim.ag/4fCsDyA | 19 commentaires sur LinkedIn

#sciencereview | Science Magazine | 19 commentaires

How Often People Use ChatGPT Across 21 Countries How often people use ChatGPT varies by country—India leads with 36% daily users, while Japan has the lowest daily adoption at 6%.

How Often People Use ChatGPT Across 21 Countries

The distribution of ~ 2 trillion immune cells in the human body. Lymphocytes: ~ 40% of the number, and 15% of the mass Neutrophils: ~ 40% of the number, and 15% of the mass Macrophages: ... The distribution of ~ 2 trillion immune cells in the human body. Lymphocytes: ~ 40% of the number, and 15% of the mass Neutrophils: ~ 40% of the number, and 15% of the mass Macrophages: ~ 10% of the number, and 50% of the mass

The distribution of ~ 2 trillion immune cells in the human body. Lymphocytes: ~ 40% of the number, and 15% of the mass Neutrophils: ~ 40% of the number, and 15% of the mass Macrophages: ...

Half a million genomes. 1.5 billion variants. One breakthrough: we are all truly unique. Twenty years ago, the Human Genome Project took 13 years and $2.7B to sequence a single genome. Today? We c... Half a million genomes. 1.5 billion variants. One breakthrough: we are all truly unique. Twenty years ago, the Human Genome Project took 13 years and $2.7B to sequence a single genome. Today? We can sequence a genome in less than 24 hours for under $1,000. Last week, UK Biobank released 490,640 whole genomes — the largest genetic dataset ever (Nature, 2025). What did we learn? • Each person carries 4–5 million variants • 76% appear in fewer than 10 people — your genome is almost entirely yours • 1 in 10 carries clinically actionable mutations where doctors can intervene today (e.g., BRCA1/2 for cancer, LDLR for heart disease) Why it matters: • Previous genetic tests captured ~6% of human variation. This dataset reveals 40× more • In non-coding regions — the biological switches controlling genes — researchers found 63 new disease associations • Adding 31,785 non-European genomes uncovered 82 disease links invisible in Eurocentric studies From genetics to health impact This transforms medicine today: • Prevention - Polygenic risk scores flag disease decades before symptoms • Diagnosis - Rare disease patients waiting years for answers finally find them • Treatment - Pharmacogenomics matches the right drug, right dose, to your genome The next frontier: genetics + everything else Genetics is the hardware. Health is the software running in real time. Your DNA is fixed, but biology is dynamic, shaped by: • Epigenetics: how environment and lifestyle switch genes on/off • Proteomics & metabolomics: molecular signals revealing your current health state • Digital biomarkers: continuous data from stress, sleep, glucose, heart rate • Stress biology & neuroendocrine signaling: how cortisol and brain-body responses reshape your health trajectory Layer these dynamic signals onto genetic foundations, power them with AI, and you create living health models, not just predicting disease, but understanding when, why, and how it manifests in YOU. The critical question? We've spent decades treating the "average patient" — who doesn't exist. Now we can better see each person as they truly are: biologically unique, dynamically changing, infinitely complex. The healthcare winners of the next decade won't just collect data: they'll integrate genetics, epigenetics, molecular and phenotypic tests, lifestyle, stress biology, and digital signals to deliver truly personalized, preventive care at scale. There is no "normal" genome, only 8 billion unique experiments in being human. And we just decoded the first half million. 👉 Which excites you more: knowing your genetic blueprint, or understanding how your daily choices rewrite it? | 47 comments on LinkedIn

Half a million genomes. 1.5 billion variants. One breakthrough: we are all truly unique. Twenty years ago, the Human Genome Project took 13 years and $2.7B to sequence a single genome. Today? We c...

💉 14 Million Nigerian Girls Protected: A Giant Leap Toward Eliminating Cervical Cancer 💪🏽 | Bloom Public Health 💉 14 Million Nigerian Girls Protected: A Giant Leap Toward Eliminating Cervical Cancer 💪🏽 Human papillomavirus (HPV) is a sexually transmitted infection that affects approximately 70% of individuals during their lifetime, with approximately 47 million women aged 15 years and older at risk of developing the disease in Nigeria. It is the leading cause of cervical cancer and cervical cancer remains one of the most preventable yet deadly threats to women and girls especially in Africa. But we are not powerless. The HPV vaccine is rewriting the story. We are proud to celebrate a historic milestone in Nigeria’s fight against cervical cancer: Over 14 million Nigerian girls have now received the HPV vaccine, according to the NPHCDA. This achievement represents not just a number. It is 14 million futures protected, 14 million girls given a chance to grow, thrive, and live free from a preventable disease. During a recent high-level panel session titled “Accelerating Cervical Cancer Elimination in Nigeria: From Policy to Practice”, experts reflected on this success while issuing a resounding call for more inclusive, innovative, and integrated efforts. 🌍 What’s needed now: ✅ Stronger community engagement ✅ Integration of HPV into ALL health and communication platforms ✅ Inclusive, gender-balanced stakeholder participation ✅ Better education of both girls and boys on HPV transmission and prevention ✅ Wider access to cervical screening and self-sampling technologies ✅ Increased research and innovation in diagnostics and vaccine accessibility Nigeria is setting the pace on the continent. But to truly eliminate cervical cancer, we must: ✅ Continue investing ✅ Continue educating ✅ Continue vaccinating ✅ Continue screening ✅ And continue the fight—together. “Let’s do it big and let’s do it together.” At Bloom Public Health, we remain committed to leading this charge through research, advocacy, partnership, and innovation. Because every girl matters. Every life counts. Saving lives should never depend on a ZIP code. Let’s unite for a future where every girl, everywhere, is protected. #BloomPublicHealth #HPVVaccine #CervicalCancerAwareness #ProtectOurGirls #ImmunizationSavesLives #EndCervicalCancer #Gavi #Unicef #PublicHealthNigeria #AfricaUnitedAgainstCancer #HealthEquity #VaccinesWork #VaccinateToEliminate #SaveHerFuture #WHO #HPV #GlobalHealth #Health #Africa #Nigeria #Lesotho #Rwanda #Zambia #Zimbabwe #Cameroon #Botswana #Ethiopia

💉 14 Million Nigerian Girls Protected: A Giant Leap Toward Eliminating Cervical Cancer 💪🏽 | Bloom Public Health

💉 14 Million Nigerian Girls Protected: A Giant Leap Toward Eliminating Cervical Cancer 💪🏽 | Bloom Public Health 💉 14 Million Nigerian Girls Protected: A Giant Leap Toward Eliminating Cervical Cancer 💪🏽 Human papillomavirus (HPV) is a sexually transmitted infection that affects approximately 70% of individuals during their lifetime, with approximately 47 million women aged 15 years and older at risk of developing the disease in Nigeria. It is the leading cause of cervical cancer and cervical cancer remains one of the most preventable yet deadly threats to women and girls especially in Africa. But we are not powerless. The HPV vaccine is rewriting the story. We are proud to celebrate a historic milestone in Nigeria’s fight against cervical cancer: Over 14 million Nigerian girls have now received the HPV vaccine, according to the NPHCDA. This achievement represents not just a number. It is 14 million futures protected, 14 million girls given a chance to grow, thrive, and live free from a preventable disease. During a recent high-level panel session titled “Accelerating Cervical Cancer Elimination in Nigeria: From Policy to Practice”, experts reflected on this success while issuing a resounding call for more inclusive, innovative, and integrated efforts. 🌍 What’s needed now: ✅ Stronger community engagement ✅ Integration of HPV into ALL health and communication platforms ✅ Inclusive, gender-balanced stakeholder participation ✅ Better education of both girls and boys on HPV transmission and prevention ✅ Wider access to cervical screening and self-sampling technologies ✅ Increased research and innovation in diagnostics and vaccine accessibility Nigeria is setting the pace on the continent. But to truly eliminate cervical cancer, we must: ✅ Continue investing ✅ Continue educating ✅ Continue vaccinating ✅ Continue screening ✅ And continue the fight—together. “Let’s do it big and let’s do it together.” At Bloom Public Health, we remain committed to leading this charge through research, advocacy, partnership, and innovation. Because every girl matters. Every life counts. Saving lives should never depend on a ZIP code. Let’s unite for a future where every girl, everywhere, is protected. #BloomPublicHealth #HPVVaccine #CervicalCancerAwareness #ProtectOurGirls #ImmunizationSavesLives #EndCervicalCancer #Gavi #Unicef #PublicHealthNigeria #AfricaUnitedAgainstCancer #HealthEquity #VaccinesWork #VaccinateToEliminate #SaveHerFuture #WHO #HPV #GlobalHealth #Health #Africa #Nigeria #Lesotho #Rwanda #Zambia #Zimbabwe #Cameroon #Botswana #Ethiopia

💉 14 Million Nigerian Girls Protected: A Giant Leap Toward Eliminating Cervical Cancer 💪🏽 | Bloom Public Health

I keep staring at this video showing the movement of aerosols in the atmosphere. | Christie Wilcox I keep staring at this video showing the movement of aerosols in the atmosphere. It's so mesmerizing! That and more of the best from Science Magazine and science in this edition of #ScienceAdviser: https://lnkd.in/gazjaRga

I keep staring at this video showing the movement of aerosols in the atmosphere. | Christie Wilcox

The immune system offers a window into aging | Nature Aging

The Alliance for Continuing Education in the Health Professions’ Position on Artificial Intelligence in CPD

INFIDEO Friday: How AI is Changing Our Search Experiences What happens when AI-infused information systems increasingly provide answers rather than directing people to sources?

INFIDEO Friday: How AI is Changing Our Search Experiences

Large language models change their ethical decisions based on a single demographic detail. | Eyal Klang posted on the topic | LinkedIn Large language models change their ethical decisions based on a single demographic detail. We tested this in 492,480 prompts with 9 models. The pattern was clear. High-income descriptors nudged models toward utilitarian reasoning. Cues about marginalized groups pulled them toward autonomy. These shifts happened even when the demographic information was irrelevant to the scenario. If this happens in triage or resource allocation, it’s not just an academic curiosity. It has real-world consequences. Vera Sorin, MD, CIIP Panagiotis Korfiatis Jeremy Collins Donald Apakama Mahmud Omar Ben Glicksberg @Mei-Ean Yeow @Megan Brandeland Girish Nadkarni https://lnkd.in/dy7FbrBb | 112 comments on LinkedIn

Large language models change their ethical decisions based on a single demographic detail. | Eyal Klang posted on the topic | LinkedIn

𝗣𝗼𝗹𝗶𝘁𝗶𝗰𝗮𝗹 𝗪𝗶𝗹𝗹: 𝗧𝗵𝗲 𝗠𝗶𝘀𝘀𝗶𝗻𝗴 𝗘𝗻𝗴𝗶𝗻𝗲 𝗼𝗳 𝗛𝗲𝗮𝗹𝘁𝗵 𝗘𝗾𝘂𝗶𝘁𝘆 | Luchuo Engelbert Bain 𝗣𝗼𝗹𝗶𝘁𝗶𝗰𝗮𝗹 𝗪𝗶𝗹𝗹: 𝗧𝗵𝗲 𝗠𝗶𝘀𝘀𝗶𝗻𝗴 𝗘𝗻𝗴𝗶𝗻𝗲 𝗼𝗳 𝗛𝗲𝗮𝗹𝘁𝗵 𝗘𝗾𝘂𝗶𝘁𝘆 Political will is the decisive force that turns health evidence into action—or leaves it stalled. It shapes priorities, allocates resources, and decides whose voices matter. Without it, even the best policies fail. In an era of widening inequities and shrinking aid, global health must stop assuming political will exists and start cultivating it—through advocacy, accountability, and coalition-building. Health without political will is like a car without an engine: it goes nowhere. "No political will, no meaningful change." Read my complete reflection on my blog @: https://lnkd.in/emms8YDj

𝗣𝗼𝗹𝗶𝘁𝗶𝗰𝗮𝗹 𝗪𝗶𝗹𝗹: 𝗧𝗵𝗲 𝗠𝗶𝘀𝘀𝗶𝗻𝗴 𝗘𝗻𝗴𝗶𝗻𝗲 𝗼𝗳 𝗛𝗲𝗮𝗹𝘁𝗵 𝗘𝗾𝘂𝗶𝘁𝘆 | Luchuo Engelbert Bain

https://kirkswearingen.medium.com/why-does-maga-hate-science-5b24bdde058f

White Rose Research Online White Rose Research Online supports OAI 2.0 with a base URL of https://eprints.whiterose.ac.uk/cgi/oai2 White Rose Research Online is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton.

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